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6 Cards in this Set

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List 2 other hereditary conditions, where there may be a combined deficiency of both B and T cells?
Wiskott-Aldrich syndrome- There are B and T cell defects, but also thrombocytpenias.
Ataxia telangiectasia, there are in addition to B cell and t cell defects, vascular malformations(hemangiomas) and neurologic problems.
What are precipitation tests?
Some tests detect a specific antibodyor antigen in the patients serum by precipitating it in the lab with corresponding antigen or antibody either in a test tube or in agar diffusion.
How may precipitation tests be facilitated?
This is done by first separating the proteins in the patients serum by electrophoresis.
The electrophoresis in itself may provide useful information about antibodies.
Most immunoglobulins fall in the gamma globulin zone. TRUE/FALSE
TRUE. A sharp spike in the gamma globulin area on electrophoresis suggests the overproduction of a single antibody, as might occur in a tumor of a single clone of plasma cells.
What is immunophelometry?
It is a technique that quantitates the amount of antigen antibody complex in solution through measuring the light scattering characteristics of the complexes.
When is immunophelometry employed?
It is used to test for C reactive protein(CRP) which rises in the acute phase of inflammation and malignancies.