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41 Cards in this Set
- Front
- Back
CRH and AVP in some species stimulates
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ACTH
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GnRH stimulates
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FSH and LH release
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TRH stimulates
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TSH release
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Dopamine inhibits
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prolactin release
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GHRH stimulates
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GH release
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somatastatin inhibits
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GH release
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ACTH release is stimulated by
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CRH
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FSH and LH release is stimulated by
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GNRH
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TSH release is stimulated by
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TRH
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Prolactin release is inhibited by
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dopamine
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Prolactin is released ______
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tonically
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GH release is inhibited by ? and stimulated by ?
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GHRH
somatastatin |
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ACTH is ? and has a half life of ? minutes.
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adrenocorticotropin
10 minutes |
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Cortisol in a ???corticoid and acts as an ?.
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glucocorticoid
anti-inflammatory |
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Cortisol is not a ? but without cortisol ? will not occur
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vasoconstrictor
constrict |
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ACTH regulation is controlled by
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light-dark cycle, daily eating patterns, and an intrinsic circadian clock in some species
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ACTH is secreted in response to
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novelty, psychogenic stress, hypotension, hypovolemia, hypoglycemia, hypoxia, pain, surgery, infection.
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ACTH negative effects are?
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slower healing
decreased muscle and bone tone. |
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Corticotrophs in the hypophysis stimulates release of ? which is post-translationally processed to?
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POMC
ACTH, MSH and other mom-biologically active fragments. |
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ACTH has a ______ feedback influence on the hypothalmus/
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negative
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The gonadotropic hormones are:
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LH, FSH, Glycoproteins produced by the anterior pituitary in response to GnRH,
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LHand FSH regulate
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estrus cycle, controls sex steroid hormone synthesis and gonadal function, growth and development.
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the hypthalamus/pituitary/gonadal axis has ____ and ______.
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negative and
positive feedback regulation |
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Growth hormone is a _________ peptide with a half-life of ____?
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protein bound
longer than 10 minutes. |
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GH secretion is stimulated by ? and inhibited by ?
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GHRH
somatostatin |
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GH causes growth of
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heart, lung, and bone
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GH causes adipose tissue to
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have lipolysis and decreased glucose uptake
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Growth Hormone causes the liver to
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glucose, IGF, IGFBP, and protein synthesis
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GH causes muscle to
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decreased glucose uptake, increased AA uptake, increase protein synthesis
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Prolactin is a ? that promotes ? and is stimulated by ? and inhibited by?
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peptide hormome
lactation, mammary development, and GnRH stimulated by setorgen, pregnancy, nursing, stress, sleep inhibited by dopamine, somatostatin, and prolactin. |
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Diseases of the anterior pituitary include
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cushings (sec hyperadrenocortisism)
secondary hypoadrenocoritisism acromegaly, dwarfism, hypo/hyperthyroid hirsuitism - in horses other |
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ADH is stimulated by
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increased ECF osmolarity
decreases in BV, BP, Glucose |
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ADH is inhibited by
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decreases in ECF osmolarity
increases in BV, BP, and glucose, ANP, ethanol, cortisol |
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ADH acts on
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distal conv. tubule of kidney to retrieve more H2O from filtrate
Acts on arteriolar smooth muscle to increase vascular tone |
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ADH (vasopressin) causes the body to be ____ and the urine to be ______.
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less salty
more salty |
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Diabetes Insipidus is characterized by ______ and caused by
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dilute urine.
hyposecretion of vasopressin |
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Oxytocin is stimulated by ? and causes?, and by ? to cause ?
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suckling
milk let down. cervical stretch uterine contraction |
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Thyroid glands are responsible for the secretion of
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thyroid hormones and calcitonin
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Thyroid hormones regulate ?
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basal metabolic rate
normal development and reproduction |
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? is the biologically active form of Thyroid hormone and is ?% of thyroid output.
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T3
10% |
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Thyroid hormones are ? soluble and ? bound so has a ? half-life
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lipid
highly protein bound long 1/2 life |