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14 Cards in this Set
- Front
- Back
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permeability of Na+ in sodium channel
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12x more permeable than K+
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amiloride
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sensitive epithelial Na+ channel (ENaC)
salt/water balance in kidneys, lungs, sweat glands, colon |
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permeability of hydrophobic molecules through lipid bilayer
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completely permeable
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permeability of small uncharged polar molecules
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selectively permeable
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permeability of large uncharged polar molecules
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not very permeable
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pore
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hydrophilic path for ions and molecules
always passive transport |
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channels/pores are 10^3 to 10^5 times faster than ______
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carriers
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aquaporin structure
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used for more rapid transport of water and glycerol
(transported slowly by lipid bilayer without channel) |
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metabotropic ion channel
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gating controlled by signaling pathways
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carriers
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change shape to move ligand across bilayer
active or passive saturates as ligand binding sites are filled |
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Na+/K+ pump characteristics
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ANTIPORT
BASOLATERAL Na+ takes some solute with it usually from ECF to intracellular fluid |
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Na+/K+ pump mechanism
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3 Na+ and ATP bind-->P stays and ADP leaves-->3 Na+ into cell-->2K bind and P leaves-->2K enter cell and ATP attaches
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secondary active transport
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uses primary Na+ gradient into cell to drive active transport of another molecule
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L-type channel activation
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beta-adrenergic-->Gs-->adenylyl cyclase-->cAMP-->PKA-->L-type channel-->Ca++ flows down gradient into cell
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