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23 Cards in this Set
- Front
- Back
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atmospheric PO2 and PCO2
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160, 0.3
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alveolar PO2 and PCO2
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100, 40
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arterial PO2 and PCO2
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100, 40
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venous PO2 and PCO2
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40, 46
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pulmonary edema
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increased thickness decreases gas exchange
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interstitial fibrosis
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alveolar inflammation, scar tissue thickens walls
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oxyHb
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red
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deoxyHb
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purple
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Hb
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4 subunits, each with an iron atom that binds 1 O2
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O2 binding curve is
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sigmoidal (due to cooperative binding)
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flat portion of curve important for
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loading O2 at lungs (higher binding affinity)
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steep portion of curve important for
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unloading of O2 at tissues (lower binding affinity)
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right shift in curve
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decreases binding affinity
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right shift due to
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increased temp/PCO2/2,3-BPG, decreased pH
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left shift in curve
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increases binding affinity
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left shift due to
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decreased PCO2/temp/2,3-BPG, increased pH
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contributors to oxygenation
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O2 uptake, content, and delivery
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alveolar gas equation
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calculates max PO2 that can exist in alveolus at a given time
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A-a gradient=
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PAO2 - PaO2 (normal is 0-15)
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PaO2 should be above
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80
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hypoxemia
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low O2 in arterial blood
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causes of hypoxemia
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low inspired O2, hypoventilation, diffusion impairment, V/Q mismatch, R-L shunt
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hypoxia
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low O2 at tissues
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