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52 Cards in this Set

  • Front
  • Back
6 functions of the kidney :
1. regulation of ECF volume and blood pressure
2. regulation of the osmolarity of ECF
3. regulation of pH of ECF
4. regulation of ion concentration in the ECF
5. produced hormones
6. excretes wastes and foreign substanced
the body recieves water through :
food, drinks, and metabolisim
the body loses water through:
skin, lungs, urine, fecies,
the bodies input must equal what?
body output
kidneys are located:
on either side of the vertebral column bellow the diaphram
parts of a kidney :
renal artery
renal vein
ureter
bladder
process of releasing urine
1. stretch receptors fire sending sensory neurons
2. parasympathetic neurons fire while motor neurons STOP firing
3. parasympathetic causes smooth muscle to contract
4. motor neurons stopped causes internal sphincter to passivly open
urine leaving the kidney must enter what before entering the ureter?
renal pelvis
what are the internal divisions of the kidney ?
outter capsule
triangle shaped medulla
cortext, just outside the medulla
renal pelvis
ureter
nephron
the functional unit of a kidney responsible for urine
different parts of the nephron:
1. glomerular capsule
2. proximal convoluted tubual
3. loop of henle
4. collecting duct
5. distal convoluted tubual
renal blood vessels include:
renal artery and vein
interlobar artery and vein
interlobular artery and vein
vascular components of nephron
afferent arterioles- blood to glomerulus
glomerulus- tuff of caps that filters protein free plasma
efferent arteriole- blood from glomerulus
peritubular caps- supply renal tissue involved in exchange with fluid in the lumen
tubular component of the nephron
bowmanc capsule- collects glomerulus filtrate
proximal tubule- uncontrolled reabsorption and secreation
loop of helne- creates osmotic gradient
distal tube/collecting duct- controlled reabsorption of Na, H2O, and secreation of K and H and releases urine to the renal pelvis
the bowmans capsule and the gomerulas together form
renal corpuscle
for the total cardiac output what % is sent to the kidneys
22,8% and the rest (77.2%) taken to the rest of the body
fenestrated
having large pore bwt the endothelial cells

(gomerulus caps have this)
the job of the gomerulus caps:
100-400times more permeable than avg. cal
keeps RBC, WBC, and platlets from passing
pore and neg. lined to keep blood proteins from passing
layers of gomerular membrane
capillary lumen
pore in the edothelial walls
filtration slits
lumen of the bowmans capsule
basal lamina
what % of plasma that enters the glomerulus is NOT filtered what % is filtered
88% is NOT
22% is
gomerulus filtration is:
nondiscriminat filtration of a protein free plasma from gomerulus into the bowmans capsule
tubular reapsortion
selective movement of filtered substance from the tubular lumen into the peritubular capilaries
tubular secretion
selection movement of nonfiltered substance from peritubluar capillaries into the tubular lumen
glomerular filtration rate (GFR)
volume of filtrate produce by both kidneys/min

-men-115
-woman-125
-avg.-180
vasoconstriction on GFR
decreases glomerulus caps blood pressure
and decrease net filtration rate
decreases GFR
vasodiolation
increases glomerulus cap blood pressure
incrases net filtrate
increases GFR
sympathetic effects:
increases cardiac output but , constricts afferent arteriole, skin, and GI tract leading to toal peripheral resistnace which decreases GFR, decreases urine production and increases blood volume
glomular ultrafiltrate IS:
fluid that enters the glomulaus whose filtration was driven by blood pressure
functions of the nephorn
reasportion of salt and water
obligatory water loss
mini of 400ml/day must be excreated from the body to eliminate wastes
reabsortion
the return of filtered molecules
water is NOT transported by travels by____?
osmosis
osmolarity of plasma is eual to what?
filtrate
sodium reabsorption is considered what type of process?
active
glucose transport is done by
help from sodium
countercurrent multiplier system
kidneys huge osmotic gradient to reabsorb a lot of H2O
which limb of the nephron is passivley permeable to water ?
descending
which limb of the nephron transports Na and Cl passivley but impermeable to water ?
ascending
urea
contributes to high osmolarity in the medulla
what is permeable to urea?
deep reagions of the collecting duct
what % of water and salt is reabsorbed?
85%(by the time gets to distal tuble) and other 15% depends on hydration levels and contolled by release of hormones
micturition
clinical term for urination
Approximately what volume of urine is produced/day
minimum "obligatory" production of urine is 400ml,
but normally about 1-2L of urine per day are produced
What type of neuron stimulates contraction of the urinary bladder
Parasympathetic neurons
what is the somatic neuron involved in
the release of urine
motor neuron that relaxes to opens the external urethral
sphincter
how many nephorns are in each kidney ?
1million
Where does
filtration occur
between the glomerulus
and Bowman's capsule
What is the composition of the
filtrate when it enters the proximal tubule
20%
What is the average volume of filtrate formed/day? What % of this is reabsorbed?
180L of filtrate are formed each day. About 99% of this is reabsorbed
How is the glomerular filtration rate (GFR) regulated?
vasoconstriction or vasodiolation of afferent arterioles
What two capillary networks are associated with each nephron. Where are they
glomerulus, and the peritubular capillary bed (which includes the
vasa recta). The glomerulus in surrounded by Bowman's capsule, and the peritubular capillary bed
surrounds the entire nephron
what portion of the nephron is most of the filtrate reabsorbed
proximal convoluted tubual