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52 Cards in this Set
- Front
- Back
6 functions of the kidney :
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1. regulation of ECF volume and blood pressure
2. regulation of the osmolarity of ECF 3. regulation of pH of ECF 4. regulation of ion concentration in the ECF 5. produced hormones 6. excretes wastes and foreign substanced |
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the body recieves water through :
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food, drinks, and metabolisim
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the body loses water through:
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skin, lungs, urine, fecies,
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the bodies input must equal what?
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body output
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kidneys are located:
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on either side of the vertebral column bellow the diaphram
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parts of a kidney :
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renal artery
renal vein ureter bladder |
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process of releasing urine
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1. stretch receptors fire sending sensory neurons
2. parasympathetic neurons fire while motor neurons STOP firing 3. parasympathetic causes smooth muscle to contract 4. motor neurons stopped causes internal sphincter to passivly open |
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urine leaving the kidney must enter what before entering the ureter?
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renal pelvis
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what are the internal divisions of the kidney ?
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outter capsule
triangle shaped medulla cortext, just outside the medulla renal pelvis ureter |
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nephron
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the functional unit of a kidney responsible for urine
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different parts of the nephron:
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1. glomerular capsule
2. proximal convoluted tubual 3. loop of henle 4. collecting duct 5. distal convoluted tubual |
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renal blood vessels include:
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renal artery and vein
interlobar artery and vein interlobular artery and vein |
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vascular components of nephron
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afferent arterioles- blood to glomerulus
glomerulus- tuff of caps that filters protein free plasma efferent arteriole- blood from glomerulus peritubular caps- supply renal tissue involved in exchange with fluid in the lumen |
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tubular component of the nephron
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bowmanc capsule- collects glomerulus filtrate
proximal tubule- uncontrolled reabsorption and secreation loop of helne- creates osmotic gradient distal tube/collecting duct- controlled reabsorption of Na, H2O, and secreation of K and H and releases urine to the renal pelvis |
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the bowmans capsule and the gomerulas together form
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renal corpuscle
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for the total cardiac output what % is sent to the kidneys
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22,8% and the rest (77.2%) taken to the rest of the body
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fenestrated
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having large pore bwt the endothelial cells
(gomerulus caps have this) |
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the job of the gomerulus caps:
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100-400times more permeable than avg. cal
keeps RBC, WBC, and platlets from passing pore and neg. lined to keep blood proteins from passing |
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layers of gomerular membrane
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capillary lumen
pore in the edothelial walls filtration slits lumen of the bowmans capsule basal lamina |
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what % of plasma that enters the glomerulus is NOT filtered what % is filtered
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88% is NOT
22% is |
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gomerulus filtration is:
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nondiscriminat filtration of a protein free plasma from gomerulus into the bowmans capsule
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tubular reapsortion
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selective movement of filtered substance from the tubular lumen into the peritubular capilaries
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tubular secretion
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selection movement of nonfiltered substance from peritubluar capillaries into the tubular lumen
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glomerular filtration rate (GFR)
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volume of filtrate produce by both kidneys/min
-men-115 -woman-125 -avg.-180 |
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vasoconstriction on GFR
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decreases glomerulus caps blood pressure
and decrease net filtration rate decreases GFR |
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vasodiolation
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increases glomerulus cap blood pressure
incrases net filtrate increases GFR |
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sympathetic effects:
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increases cardiac output but , constricts afferent arteriole, skin, and GI tract leading to toal peripheral resistnace which decreases GFR, decreases urine production and increases blood volume
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glomular ultrafiltrate IS:
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fluid that enters the glomulaus whose filtration was driven by blood pressure
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functions of the nephorn
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reasportion of salt and water
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obligatory water loss
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mini of 400ml/day must be excreated from the body to eliminate wastes
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reabsortion
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the return of filtered molecules
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water is NOT transported by travels by____?
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osmosis
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osmolarity of plasma is eual to what?
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filtrate
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sodium reabsorption is considered what type of process?
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active
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glucose transport is done by
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help from sodium
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countercurrent multiplier system
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kidneys huge osmotic gradient to reabsorb a lot of H2O
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which limb of the nephron is passivley permeable to water ?
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descending
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which limb of the nephron transports Na and Cl passivley but impermeable to water ?
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ascending
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urea
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contributes to high osmolarity in the medulla
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what is permeable to urea?
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deep reagions of the collecting duct
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what % of water and salt is reabsorbed?
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85%(by the time gets to distal tuble) and other 15% depends on hydration levels and contolled by release of hormones
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micturition
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clinical term for urination
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Approximately what volume of urine is produced/day
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minimum "obligatory" production of urine is 400ml,
but normally about 1-2L of urine per day are produced |
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What type of neuron stimulates contraction of the urinary bladder
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Parasympathetic neurons
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what is the somatic neuron involved in
the release of urine |
motor neuron that relaxes to opens the external urethral
sphincter |
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how many nephorns are in each kidney ?
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1million
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Where does
filtration occur |
between the glomerulus
and Bowman's capsule |
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What is the composition of the
filtrate when it enters the proximal tubule |
20%
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What is the average volume of filtrate formed/day? What % of this is reabsorbed?
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180L of filtrate are formed each day. About 99% of this is reabsorbed
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How is the glomerular filtration rate (GFR) regulated?
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vasoconstriction or vasodiolation of afferent arterioles
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What two capillary networks are associated with each nephron. Where are they
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glomerulus, and the peritubular capillary bed (which includes the
vasa recta). The glomerulus in surrounded by Bowman's capsule, and the peritubular capillary bed surrounds the entire nephron |
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what portion of the nephron is most of the filtrate reabsorbed
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proximal convoluted tubual
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