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7 Cards in this Set

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Unless injected intravenously, Administration of a drug by any route is followed by movement of the drug from the site of administration into the (blood) plasma through a process of
Absorption.
Absorption.
Once in the plasma, the drug may exist as
Free Drug or as Bound Drug.
Drug in the plasma is delivered to organs, tissues and cells in the body through the process of
Distribution.
What is Distribution.
The Movement of Drug Molecules Across Membranes across a cell membrane and across cell layers as it passes to or from the plasma, or into or out of cells of a particular tissue or organ, can occur through several processes.
What happens during Distribution?
In some cells, tissues and organs, Storage of the drug may occur; in others, Metabolism of the drug may occur.
Delivery of the drug to some organs may lead to Excretion of the drug. In order for its action to be terminated, a drug must either be
metabolized or excreted:
the sum of the processes of metabolism and of excretion is known as ?
Elimination.