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Pharmacokinetics

how medications travel through the body. Absorption; distribution; metabolism; excretion.

Four processes.

Tachyphylaxis

Diminishing drug response top successive doses of drug. Common on nervous system drugs.

Protein binding

Medications compete for protein binding sites within the bloodstream, primarily albumin. The ability of a medication to bind to a protein can a ect how much of the medication will leave and travel to target tissues. Two medications can compete for the same binding sites, resulting in toxicity.