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31 Cards in this Set
- Front
- Back
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What kinds of things increase uterine contractility?
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Estrogens, prostaglandins, oxytocin, and stretching
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What things relax the uterus?
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progesterone, booze, MgSO4
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How do oxytocin receptors change before labor?
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they increase in number and sensitivity
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When are prostaglandins used to induce labor?
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in the 2nd trimester abortions
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when is oxytocin used to induce labor?
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at term
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What is the main cause of post partum hemorrhage?
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uterine atony- the uterine muscles not contracting hard enough
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what is the first line treatment for PPH?
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uterine massage
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What is Oxytocin given for?
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this is used to induce labor at term
also prevents hemorrhage |
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How is Oxytocin given?
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IV, IM, or nasal route
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What are the adverse effects of Oxytocin
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Water intoxication (due to ADH effect)
Uterine rupture Anaphylaxis Sinus bradycardia |
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What kind of drug is Ergonovine maleate?
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this is used to induce uterine contraction after delivery to reduce bleeding
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What kind of drug is methylergonovine maleate?
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this is used to induce uterine contraction after delivery to reduce bleeding
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Can you use ergot alkaloids like Ergonovine maleate and methylergonovine maleate to induce labor?
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NO because the uterine contraction is strong and continuous and will kill the baby
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What is Dinoprostone?
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this is a synthetic prostaglandin E2
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What is Dinoprostone given for?
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this is used to expel uterine contents for a number of reason, like abortions
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What are the common side effects of Dinoprostone?
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GI disturbances, vomiting, diarrhea- can be very serious
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What kind of drug is Carboprost tromethamine?
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this is a PGF2alpha derivativve
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What is Carboprost tromethamine used for?
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this is used for 2nd trimester abortions
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How is Carboprost tromethamine given?
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IM administration
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What are the side effects of Carboprost tromethamine?
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Vomiting and diarrhea
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What are the contraindications to using Carboprost tromethamine?
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ACUTE cardiac, pulmonary, renal, or hepatic diseases
ashtma, HTN, anemia, jaundice, or epilepsy |
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What is premature labor?
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sustained uterine contractions before the 37th week
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How do you rush development of fetal lungs before the 37th week?
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corticosteroids are used to help fetal lung development
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What is magnesium sulfate used for?
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this is used to relax uterine muscle by a direct effect
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is magnesium sulfate FDA approved for premature labor tx?
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NO it is not
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What kind of drug is Nifedipine?
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this is a calcium channel blocker, and smooth muscle relaxant- used to delay preterm labor
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What kind of drug is Indomethacin?
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this is an NSIAD - used to delay preterm labor
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What is the main adverse effect of Indomethacin?
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partial closure of fetal ductus arteriosus
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What is progesterone used to prevent?
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this is given prophylactically to prevent pre term delivery
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What is nirtoglycerin used for?
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this is used for Emergencies, with uterine rupture
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What is Ethanol used for?
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tx or premature labor
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