Pharmacology Unit 1 & 2 Test

Front 1

The broadest term for the study or science of drugs

Back 1

Pharmacology

Front 2

Name given by the US Adopted Names Council -

Back 2

Generic name

Front 3

The generic name becomes this -

Back 3

Official name

Front 4

Proprietary name & registered trademark -

Back 4

Trade name

Front 5

Study of what body does to the drugs

Back 5

Pharmacokinetics

Front 6

ADME stands for

Back 6

Absorptions
Distribution
Metabolism
Excretion

Front 7

Rate at which the drug leaves the site of administration and the extent to wihch it occurs

Back 7

Adsorption

Front 8

Biologic transformation of a drug into an inactive metabolite, a more soluble compound, or a more potent metabolite -

Back 8

Metabolism

Front 9

The elimination of the drug from the body

Back 9

Excretion

Front 10

Enteral Route means medications are taken how?

Back 10

orally / swallow

Front 11

The study of what happens to the drug from the time it enters the body until it and all its metabolites are excreted.

Back 11

Pharmakokinetics

Front 12

Transport of a drug in the body by the bloodstream to its site of action -

Back 12

Distribution

Front 13

Drugs that are absorbed through the GI tract will pass through the liver and begin to be metabolized before getting to the systemic circulation -

Back 13

First pass effect

Front 14

This reduces the bioavailability of a drug to less than 100% -

Back 14

First pass effect

Front 15

Which dosage form is absorbed into circulation from the stomach or small intestine -

Back 15

Enteral

Front 16

Which dosage form do drugs not pass thru the GI tract?

Back 16

Parenteral

Front 17

Name the dosage form where drugs are applied to a body surface?

Back 17

Topical

Front 18

This dosage route passes thru the GI tract -

Back 18

Enteral

Front 19

What types of things can affect absorption -

Back 19

dosage form
acid changes in stomach
absorption changes in the intestine (diarrhea)
Presence / absence of food
Application of heat or cold
Massage
Condition of the skin (blister/cut)

Front 20

The major protein that binds during distribution is -

Back 20

Albumin

Front 21

During distribution these bind to and carry drugs throughout the body -

Back 21

3 proteins

Front 22

What should you do is your patients albumin level is too low?

Back 22

Check the dosage and lower it (call doctor for prescription change)

Front 23

What major organ is involved in metabolism?

Back 23

Liver

Front 24

Biostransformation happens during which phase?

Back 24

Metabolism

Front 25

What can affect the metabolism of drugs?

Back 25

Liver issues - alcoholic

Front 26

What is the result of metabolism -

Back 26

increase the water solubility and ease of excretion

Front 27

Elimination from the body is known as -

Back 27

Excretion

Front 28

The major organ involved in excretion is -

Back 28

Kidney

Front 29

Site of Glomerular Filtration -

Back 29

Kidney

Front 30

This organ takes the drug and releases it into bile and excretes it in stool -

Back 30

Liver

Front 31

The time it takes for 1/2 of the original amount of the drug to be excreted.

Back 31

half-life

Front 32

The amount of drug excreted is equal to the amount absorbed with each dose -

Back 32

Steady state

Front 33

Time required for the or the drug to give a therapeutic response -

Back 33

Onset

Front 34

Time required for the drug to give the maximum therapeutic response -

Back 34

Peak

Front 35

Length of time that the drug concentration is high enough to give a therapeutic response -

Back 35

Duration

Front 36

The study of what the drug does to the body

Back 36

Pharmacodynamics

Front 37

In pharmacodynamics what are the three mechansims of action -

Back 37

receptor interaction
enzyme interaction
non-specific interaction

Front 38

A reactive site on the surface of a cell or tissue -

Back 38

receptor

Front 39

What binds with the receptor to produce the pharmacologic response -

Back 39

a drug molecule

Front 40

These drugs bind to the receptor site and cause a response -

Back 40

agonist

Front 41

These drugs bind to a receptor site and stop the response -

Back 41

antagonist

Front 42

During this interaction a drug alters a physiologic response by inhibiting a certain enzyme by "fooling" the enzyme into binding to it instead of the normal target cells -

Back 42

enzyme interaction

Front 43

During this type of interaction no receptors or enzymes are involved and the cell's membranes and various cellular processes are the main site of action -

Back 43

non-selective interactions

Front 44

What affects drug therapy effectiveness?

Back 44

dose (duration)
route (how fast work/absorbed)
health status of patient
gender
nutritional/fluid balance

Front 45

The treatment of pathological conditions through the use of drugs -

Back 45

Pharmacotherapeutics

Front 46

List the 4 aspects of pharmacotherapeutics -

Back 46

Assessment
Implementation
Monitoring
Reassessment

Front 47

The first step of the nursing process is

Back 47

Assessment

Front 48

Lookng at the patients medical and social history as well as current medications being used, pregnancy, and current illnesses is done during which process -

Back 48

Assessment

Front 49

Initiation of the drug therapy is done during which process -

Back 49

implementation

Front 50

This process involves evaluating -

Back 50

Monitoring

Front 51

Ratio between a drugs therapeutic benefit adn its toxic effects(can have a very narrow window) -

Back 51

Therapeutic index

Front 52

Levels drawn to determine either therapeutic levels or toxic levels is known as -

Back 52

Drug concentration

Front 53

Decreasing response to repetative doses -

Back 53

Tolerance

Front 54

Physiologic or psychologic need for a drug -

Back 54

dependence

Front 55

Can you take medications with antacids?

Back 55

No

Front 56

Alteration of the action of one drug by another -

Back 56

interaction

Front 57

ADE stands for

Back 57

adverse drug events

Front 58

Adverse effects is also known as -

Back 58

side effects

Front 59

Are side effects predictable?

Back 59

Yes

Front 60

An extension of the drug's effects (lowers the BP too much)

Back 60

Pharmacologic

Front 61

No reason is known for the reaction - genetic trait -

Back 61

Idosyncratic

Front 62

The patients immune system sees the drug as a dangerous foreign substance and tries to eliminate it by causing an allergic reaction -

Back 62

Hypersensitivity

Front 63

Two drugs interact and produce an unwanted effect -

Back 63

Drug interaction

Front 64

The patients condition changes and the treatment plan should be changed to accomodate -

Back 64

reassessment

Front 65

The study of drug sources or origins -

Back 65

Phamacognosy

Front 66

The 4 major sources of Pharmacognose are

Back 66

plants (foxglove)
animals - horses (hormones)
laboratory synthesis - (recombinant DNA)
minerals (aluminum hydroxide (antacids)

Front 67

Which Act protected the public from adulterated or mislabeled drugs, packing to state presence of dangerous or addicting drugs and designated USP and NF as official standards?

Back 67

Pure Food & Drug Act of 1906

Front 68

Which Act prohibited marketing of drugs before safety testing -

Back 68

Food, Drug & Cosmetic Act of 1938

Front 69

What Act designated certain drugs as "legend drugs" and make have a prescription requred -

Back 69

Durham-Hump