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9 Cards in this Set

  • Front
  • Back
  • 3rd side (hint)

Morphine & Fentanyl as PCA

Opioid effects, receptors & locations

CNS


  • analgesia
  • sedation
  • euphoria & tolerance
  • N & V
  • hyperalgesia

CVS


  • SNS
  • PNS
  • HR

RESP


  • RR
  • VM

Other


  • histamine
  • constipation
  • immunological

Analgesic effects of opioids

Cellular effects


Supraspinal


Spinal


Peripheral



For each write about


  • receptor
  • location
  • effects

Remifentanil PC & PK

Remifentanil PD

Effects of intrathecal opioids

Use


MOA


Drugs


PK differences


Effects


  • analgesia
  • resp depression
  • urinary retention
  • n&v
  • pruritis

Opioid acute adverse effects

NA


  • resp depression
  • urinary retention
  • pruritis
  • N&V

Systemic


CNS


  • sedation
  • miosis
  • seizure

CVS


  • bradycardia
  • hypotension

RESP


  • resp depression
  • response to CO2 & O2
  • cough & airway reflex's
  • chest wall rigidity

GIT


  • N&V
  • biliary spasm

Other


  • histamine release

PD differences between morphine and tramadol

MOA


Use


CNS


  • analgesia
  • sedation
  • euphoria
  • miosis
  • serotonin

CVS


  • ANS
  • BP
  • HR

Resp


  • depression
  • cough

GIT


  • N&V
  • constipation

Other


  • histamine
  • metabolism
  • urinary retention

PK differences between fentanyl and alfentanil

Time course


PK


  • D
  • M
  • E

CSHT


Graph