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33 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Edrophonium |
Cholinoceptor agonist Myasthenia gravis |
Indirect-acting |
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Physostigmine |
Cholinoceptor agonist Glaucoma Antidote in atropine overdose |
Indirect-acting |
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Pyridostigmine, Neostigmine |
Cholinoceptor agonist Myasthenia gravis Reversal of NM blockers |
Indirect-acting |
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Donepezil, Tacrine |
Cholinoceptor agonist Alzheimer's |
Indirect-acting |
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Organophosphates |
Cholinoceptor agonist Insecticides, nerve gas |
Indirect-acting |
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Atropine |
Cholinoceptor antagonist Cholinergic crisis, ophtha, diarrhea |
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Tropicamide, Cyclopentolate |
Cholinoceptor antagonist Ophtha (diagnostic) |
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Ipratropium, Tiotropium |
Cholinoceptor antagonist Asthma & COPD |
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Scopolamine |
Cholinoceptor antagonist Motion sickness |
Buscopan |
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Benztropine |
Cholinoceptor antagonist Parkinson's |
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Tetraethylammonium (TEA) |
Ganglion blocker First ganglion-blocking drug |
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Hexamethonium, Trimethapan |
Ganglion blocker Hypertension |
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Mecamylamine |
Ganglion blocker Reduce nicotine craving |
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Tubocurarine, Atracurium |
NMJ Blocker Flaccid paralysis ADE: Releases histamine |
Non-depolarizing |
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Pancuronium |
NMJ Blocker Flaccid paralysis Does not release histamine |
Non-depolarizing |
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Succinylcholine |
NMJ Blocker Endotracheal tubing, setting fractures ADE: Malignant hyperthermia |
Depolarizing |
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Hemicholiniums |
Cholinergic junction Blocks CHT (membrane choline transporter) |
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Vesamicol |
Cholinergic junction Blocks VAT (vesicle-associated transporter) |
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Botolinium toxin (Botox) |
Cholinergic junction Blocks calcium receptors of presynaptic membrane |
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Metyrosine |
Adrenergic junction Inhibits tyrosine hydroxylase |
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Reserpine |
Adrenergic junction Blocks VMAT (vesicular monoamine transporter) |
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Bretylium, Guanethedine |
Adrenergic junction Blocks release of neurotransmitters |
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Cocaine, Tricyclic antidepressants |
Adrenergic junction Inhibits NET (Norepinephrine transporter) |
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Phenylephrine |
Alpha-1 agonist Nasal decongestant Mydriasis without cycloplegia |
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Methoxamine |
Alpha-1 agonist Paroxysmal atrial tachychardia Vagal reflex |
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Clonidine |
Alpha-2 agonist Lowers BP Can cause rebound hypertension |
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Alpha methyldopa |
Alpha-2 agonist Lowers BP Prodrug (forms alpha methylNE) |
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Bethanechol |
Cholinergic agonist Induce peristalsis Paralytic ileus, urinary retention |
Direct-acting |
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Methacholine |
Cholinergic agonist Bronchial hyperreactivity |
Direct-acting |
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Pilocarpine |
Cholinergic agonist Glaucoma, Xerostomia |
Direct-acting |
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Nicotine, Lobeline |
Cholinergic agonist Smoking cessation |
Direct-acting |
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Isoprotenol |
Beta agonist Bronchospasm, heart block, bradyarrythmias ADE: Flushing, angina, arrythmia |
B1=B2 |
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Dobutamine |
Beta agonist Chronic heart failure ADE: Tachyphylaxis |
B1>B2 |
