1. Stable angina Base on what i read in the e-book "It is characteristically caused by a fixed obstruction in a coronary artery." For example for example. It has a regular pattern, and if you already know that you have stable angina, you will be able to predict the pattern. Once you stop exercising, or take medication (usually nitroglycerin) the pain goes away, usually within a few minutes.
2. Variant or vasospastic angina
The e-book reading tells us that" In the result of a coronary artery spasm that reduces blood flow. It usually occurs at rest rather than with exertion or emotional stress." The Heart and Stroke also said is also known as Prinzmetal’s angina. It often occurs while someone is resting (usually between midnight and 8:00 …show more content…
Unstable angina
According to the e-book "Unstable angina is caused by significant CAD. It occurs at rest for the first time and decreases in response to rest or nitroglycerin. It often portends an MI." The Heart and Stroke also said Unstable angina "Is more serious, and may be a sign that a heart attack could happen soon. There is no predictable pattern to this kind of angina; it can just as easily occur during exercise as it can while you are resting. It should always be treated as an emergency. People with unstable angina are at increased risk for heart attacks, cardiac arrest, or severe cardiac arrhythmias (irregular heartbeat or abnormal heart rhythm)."
Explain the mechanism of action of the classes of antianginal drugs (i.e. how do they work?)
"Angina pectoris is usually the first clinical sign of underlying myocardial ischemia, which results from an imbalance between oxygen supply and oxygen demand in the heart. The three classes of antianginal drug are organic nitrates, beta-adrenergic blockers (beta-blockers), and calcium channel blockers."
1. Organic nitrates
2. Beta-adrenergic blockers (also called beta-blockers)
3. Calcium channel …show more content…
Beta-adrenoceptor antagonists may be used in combination with nitrates or calcium channel blockers, which takes advantage of the diverse mechanisms of action of drugs from each pharmacologic category. Moreover, concurrent use of β-adrenoceptor antagonists may alleviate the reflex tachycardia that sometimes occurs with other antianginal agents. "
How Does It Works
The e-book stated that " Ntiroglycerin directly affects the vascular smooth muscle to dilate blood vessels. It decreases cardiac oxygen demand in stable angina, but in variant angina, it relaxes the spasms and increases oxygen
2. Variant or vasospastic angina
The e-book reading tells us that" In the result of a coronary artery spasm that reduces blood flow. It usually occurs at rest rather than with exertion or emotional stress." The Heart and Stroke also said is also known as Prinzmetal’s angina. It often occurs while someone is resting (usually between midnight and 8:00 …show more content…
Unstable angina
According to the e-book "Unstable angina is caused by significant CAD. It occurs at rest for the first time and decreases in response to rest or nitroglycerin. It often portends an MI." The Heart and Stroke also said Unstable angina "Is more serious, and may be a sign that a heart attack could happen soon. There is no predictable pattern to this kind of angina; it can just as easily occur during exercise as it can while you are resting. It should always be treated as an emergency. People with unstable angina are at increased risk for heart attacks, cardiac arrest, or severe cardiac arrhythmias (irregular heartbeat or abnormal heart rhythm)."
Explain the mechanism of action of the classes of antianginal drugs (i.e. how do they work?)
"Angina pectoris is usually the first clinical sign of underlying myocardial ischemia, which results from an imbalance between oxygen supply and oxygen demand in the heart. The three classes of antianginal drug are organic nitrates, beta-adrenergic blockers (beta-blockers), and calcium channel blockers."
1. Organic nitrates
2. Beta-adrenergic blockers (also called beta-blockers)
3. Calcium channel …show more content…
Beta-adrenoceptor antagonists may be used in combination with nitrates or calcium channel blockers, which takes advantage of the diverse mechanisms of action of drugs from each pharmacologic category. Moreover, concurrent use of β-adrenoceptor antagonists may alleviate the reflex tachycardia that sometimes occurs with other antianginal agents. "
How Does It Works
The e-book stated that " Ntiroglycerin directly affects the vascular smooth muscle to dilate blood vessels. It decreases cardiac oxygen demand in stable angina, but in variant angina, it relaxes the spasms and increases oxygen