Pharm Test 9

Front 1

mechanism of aminoglycosides

Back 1

bacterialcidal, disrupt bacteria protein synthesis via 30s ribosmal subunit

Front 2

name four aminoglycosies

Back 2

gentamicin, streptomycin, neomycin

Front 3

aminoglycosides drug of choice against (4)

Back 3

e coli, k pneumoniae, mirabilis, pseumonas aeru

Front 4

for tape worm

Back 4

paromomycin

Front 5

used prior to GI surgery

Back 5

oral neomycin

Front 6

this aminoglycoside used for tb, gram pos, gram neg, and acid fast infections

Back 6

streptomycin

Front 7

four adverse of aminoglycosides

Back 7

hearing, kidneys, weakness, rash

Front 8

tests for kidneys (2)

Back 8

elevated BUN and creatinine

Front 9

normal BUN

Back 9

10-20

Front 10

normal creatinine

Back 10

0.5-1.1

Front 11

side effect of streptomycin

Back 11

neuro tingling in extremeties

Front 12

paresthesias means

Back 12

neuro tingling

Front 13

myasthenia gravis is

Back 13

condition with weakness of voluntary muscles

Front 14

do not use this with aminoglycosides in same IV bag as it will disactivate aminoglycosides

Back 14

penicillins

Front 15

other medication that can intensify ototoxicity of aminoglycosides

Back 15

loop diuretic (furosemide) lasix

Front 16

normal peak level range of gentamicin (to be checked 30 minutes after completiion of divides doses/infusions)

Back 16

4-10

Front 17

normal trough level range of gentamicin (checked right before next dose)

Back 17

< 2

Front 18

loop diuretic other than furosemide (lasix) that can incrase ototoxicity when used in conjuction with aminoglycosides such as gentamicin

Back 18

ethacrynic acid

Front 19

aminoglycosides should be infused over at least

Back 19

30 minutes

Front 20

besides blood urea nitrogen (BUN) and creatinine, this also shows possible kidney damage

Back 20

protein in urine

Front 21

first sign of vestibular (balance) damage

Back 21

headache

Front 22

most important assessment in myasthenia gravis (muscle weakness)

Back 22

breath sounds

Front 23

first sign of cochlear ototoxicity (hearing) is

Back 23

tinnitus (ringing in ears)

Front 24

sulfonamides mechanism

Back 24

inhibit synthesis of precursor to folate which bacteria have to make. we just eat it in our diet.

Front 25

sulfonamides are bacterio_______

Back 25

bacteriostatic (stop growth)

Front 26

sulfonamides and trimethoprim used for

Back 26

UTI's

Front 27

causes of UTI's

Back 27

e coli, ghonorreha

Front 28

SMZ-TMP also used for

Back 28

pneumocystis j pneumonia (PCP)

Front 29

those with allergies to these 2 might have allergies to SMZ-TMP uti meds

Back 29

sulfa(o)s and diuretics

Front 30

5 adverse of sulfonamide/trimethoprim

Back 30

stevens johnson rash, anemia, crystalluria, kernicterus, light

Front 31

kernicterus means increased ________ which leads to _______

Back 31

increased bilirubin leads to neurotoxicity

Front 32

kernicterus especially dangerous in pregnant women and children under

Back 32

children under 2 months

Front 33

sulfonamides (uti med) can increase effects of (3) drugs

Back 33

warfarin, phenytoin, hypoglycemics

Front 34

name 2 fluoroquinolone antibiotics

Back 34

ciprofloxacin and levoflox

Front 35

ciproflox primary for

Back 35

anthrax

Front 36

four adverse of ciproflox (fluoroquinolones)

Back 36

achilles tendon, GI, suprainfection, light

Front 37

avoid ciproflox antibiotics in children due to achilles rupture unless (2)

Back 37

e coli, anthrax

Front 38

avoid these cationic compounds with antibiotic ciproflox

Back 38

magnesium, anatcids, mulk, iron

Front 39

ciproflox bad with this bronchodilator

Back 39

theophylline

Front 40

infuse ciproflox over at least

Back 40

60 minutes

Front 41

ciproflox primarily for

Back 41

UTI

Front 42

adverse unique to trimethoprim (for UTI)

Back 42

hyperkalemia

Front 43

sulfonamide for burns

Back 43

sulfamylon

Front 44

sulflo/trim should be avoided in those with these disease that causes low folic acid

Back 44

alcoholics

Front 45

sulfamylon for burns may cause

Back 45

acidosis

Front 46

urticaria means

Back 46

hives

Front 47

3 symptoms of hemolytic anemia

Back 47

jaundice, pallor, fever

Front 48

four medications for tb

Back 48

isoniazid, pyrazinamide, rifampin, ethambutol

Front 49

ethambutol bactero_____ to myco tubercolsis

Back 49

bacteriostatic

Front 50

initial phase of tb treatment lasts

Back 50

2 months

Front 51

continuation phase of tb treatment lasts

Back 51

4 months

Front 52

symptoms of tb (4)

Back 52

cough of 3 weeks or more, weight loss, night sweats, and fever.

Front 53

adverse of Isoniazid (3)

Back 53

neuropathy, hepatitis, hyperglycemia

Front 54

for neuropathy give

Back 54

vitamin b6

Front 55

old standard treatment for tb

Back 55

isoniazid daily for 9 months

Front 56

new standard treatment for tb

Back 56

isonizid plus rifapentine once a week for 3 months

Front 57

optic neuritis really only happens with this tb drug

Back 57

ethambutol

Front 58

signs of tb induced hepatitis

Back 58

yellow eyes, jaundice

Front 59

those taking tb meds must avoid blank to protect liver

Back 59

alcohol

Front 60

ataxia

Back 60

loss of body movements

Front 61

labs that show bad liver (tb med induced hepatitis)

Back 61

AST high

Front 62

normal ast

Back 62

10-40

Front 63

INH interaction with this drug

Back 63

phenytoin builds up thus too much seizure suppression means ataxia

Front 64

drug for leprosy

Back 64

rifampin

Front 65

3 side effects of rifampin

Back 65

orange bodily fluids, hepatoxicity, GI

Front 66

rifampin interactions (3)

Back 66

contraceptives, warfarin, HIV meds NNRTI's

Front 67

med for leprosy

Back 67

rifampin

Front 68

INH administration make sure no

Back 68

crystals in solution

Front 69

adverse of pyrazinamide (2)

Back 69

liver and joint pain

Front 70

ethambutol adverse (1)

Back 70

optic neuritis - color vision

Front 71

during last two months (cont phase) of tb treatment only give these two

Back 71

isoniazid and rifampin

Front 72

sizes of ppd induration that determine positive result of tb in those who are high risk, mod risk, low risk

Back 72

5, 10, 15 mm

Front 73

dosing of rifampin for leprosy

Back 73

once per month for 12 months

Front 74

daptomycin is

Back 74

antibiotic that can kill al gram positive (no extra layer) bacteria

Front 75

daptomycin used for (2)

Back 75

staph infections

Front 76

adverse of daptomycin (2)

Back 76

myopathy, check CKP

wbc pneumonia - rare

Front 77

metronidazole

Back 77

antiprotozoa flagyl

Front 78

uses for flagyl (3)

Back 78

c dif

joint

vaginal

Front 79

adverse of flagyl (3)

Back 79

dark urine, GI, seizures

Front 80

flagyl interactions

Back 80

alcohol (bad disulfiram)

warfarin

Front 81

rifampin for tb, leprosy, and

Back 81

meningitis caused by Haemophilus influenzae