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28 Cards in this Set

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This drug inhibits sodium and chloride reabsorption in distal tubule
Thiazide diuretics - hydrochlorothiazide, chlorthalidone
Side effects of thiazide diuretics
Hypokalemia
Hypomagnesemia
Hypercalcemia
Hyperuricemia
Rash
Hyperglycemia
Which tests should be monitored in patients with thiazide diuretics
Potassium every 3 days until stable then every several months, blood glucose, serum magnesium
Side effects of loop diuretics
Hypokalemia
Hypomagnesemia
Hypocalcemia
Hyponatremia
Ototoxicity
Hypersensitivity
Renal function
Which tests should be monitored in patients with loop diuretics
Electrolytes every 3 days, look for signs of hypokalemia, patient weight monitor
These drugs are indicated for all patients with CHF and HOPE trial suggests all patients with atherosclerotic disease and diabetics with one or more risk factors
ACE inhibitors
Side effects of ACE inhibitors
Hypotension
Hyperkalemia
Renal failure
Cough
Rash
Taste disturbance
Neutropenia
Pancreatitis
These drugs should be initial drug therapy for most either alone or combined with other drug classes for hypertension
Thiazide diuretics
DOC heart failure + HTN
Thiazides
Beta blockers
ACE inhibitors
ARB
Aldosterone antagonists
DOC post MI + HTN
Beta blockers
Ace inhibitors
Aldosterone antagonists
DOC high CAD risk + HTN
Thiazides
Beta blockers
Ace inhibitors
Ca channel blockers
DOC diabetes + HTN
Thiazides
Beta blockers
ACE inhibitors
ARB
CA channel blockers
DOC Chronic kidney disease + HTN
ACE inhibitors
ARB
DOC recurrent stroke prevention + HTN
Thiazides
ACE inhibitors
Drugs contraindicated for treatment of HTN in pregnancy
ACE inhibitors
ARB
DOC osteoporosis + HTN
Thiazide diuretics
DOC atrial arrhythmias/fibrillation, migraine, thyrotoxicosis, essential tremor or pre op HTN
Beta blockers
Useful in treatment of Raynauds and certain arrhythmias + HTN
Ca channel blockers
Used in prostatism + HTN
Alpha blockers
Should be used cautiously in gout or history of significant hyponatremia
Thiazide diuretics
Should be avoided in patients with asthma, reactive airway diseases, or 2nd, 3d degree heart block
Beta blockers
Should not be used in individuals with history of angioedema
ACE inhibitors
Can cause hyperkalemia
K sparing diuretics + aldosterone antagonists
Contraindications for niacin
Liver disease
Severe gout
Peptic ulcer
Side effects niacin
Flushing
Hypeglycemia
Hyperuricemia
Upper GI distress
Side effects fibric acids
Dyspepsia
Gall stones
Myopathy
Contraindications fibric acids
Severe renal or liver disease
Acts at intestinal brush border, reduces cholesterol, LDL, TG - well tolerated, used in combination with HMG
Ezetimibe