Pharm Quiz 8 - Antimicrobials

Front 1

name an example of antagonistic antibiotics

Back 1

tetracyclin and penacillin

Front 2

which disease REQUIRES multi drug to prevent resistance

Back 2

tubercolisis

Front 3

in this type of surgery, antibiotics considered treatment not prophylactic

Back 3

contaminated surgery (perforated abdominal organs, compound fractures, lacerations from animal bites)

Front 4

for most post ops, this first gen drug will suffice if anything is needed at all

Back 4

cephalosporin

Front 5

FUO means

Back 5

fever of unknown origin

Front 6

only give antibiotics to patients with FUO who...

Back 6

are immunocompromised

Front 7

bacteria with this gene are resistant to nearly all available antibiotics

Back 7

NDM-1

Front 8

MIC vs MBC

Back 8

minimum inhibitory concentration (bacteriostatic)

minimum bactericidal concentration (bactericidal0

Front 9

pencillins act by

Back 9

weakening cell wall

Front 10

penicillin resistant bacteria produce ___ to inactivate penacillin's cell wall weaking action

Back 10

beta-lactamases

Front 11

penacillins are typically more effection on Gram-_______ bacteria

Back 11

Gram-positive

Front 12

number adverse of penacillins

Back 12

allergic reactino, anaphylaxis

Front 13

patients allergic to penacillins also have a 1% chance of cross-allergy to __________________

Back 13

cephalosporins

Front 14

three safe alternatives for those allergic to penacillin

Back 14

vancomycin, erythomycin, clindamycin

Front 15

penacillilns eliminated (metabolised) by _______

Back 15

kidneys

Front 16

penacillins differ within drug family due to (3)

Back 16

spectrum, stability in stomach acid, and duration

Front 17

penacillin G has _________________ spectrum

Back 17

narrow

Front 18

penacillin G _____________ in stomach acid

Back 18

unstable

Front 19

__________ pen G is released slowly following IM and has long effects

Back 19

benzathine pen G

Front 20

this penicillinase resistant penicillin used against staph. aureus (staph infections)

Back 20

nafcillin

Front 21

these two broad spectrum penacillins useful against gram-negative bacteria

Back 21

ampicillin and amoxicillin

Front 22

these two extended spectrum good against multi drug resistant Pseudomonas aeruginosa (sepsis, ventillator related)

Back 22

piperacillin

ticarcillin

Front 23

this beta-lactamase inhibitor combined with penicillins to increase their activity against beta-lactamase bacteria

Back 23

clavulanic acid

Front 24

penacillins should not be combined with _______________ in the sam IV solution

Back 24

aminoglycosides (gentamicin)

Front 25

use penacillins with caution in patients who have had allergic reaction to these two

Back 25

cephalosporins

carbapenems

Front 26

doses for pen G in units. 1 unit of pen g = _____ mg

Back 26

1 unit Pen G = 0.6 mg

Front 27

take most pen G ________ before meals or ____________ after meals

Back 27

1 hour before meals or 2 hours after meals

Front 28

monitor _______ to aoid penicillin toxicity

Back 28

renal function

Front 29

use ________ for Penicillin allergic reaction

Back 29

epinephrine

Front 30

this sodium pen G can cause fluid overload in cardiac patients

Back 30

ticarcillin

Front 31

this pen G may cause hyperkalemia

Back 31

potassium pen G

Front 32

do not mix penicillin with this in IV because it can deactivate this drug

Back 32

gentamicin (aminoglycosides)

Front 33

one aminoglycoside

Back 33

gentamicin

Front 34

generic name of Penicillin G

Back 34

benzylpenicillin

Front 35

pen G good for these six diseases

Back 35

pneumonia, strep throat, gangrene, tetanus, anthrax, syphillis

Front 36

pen G good as prophylactic for

Back 36

heart valve

Front 37

oral admin of pen G

Back 37

obsolete, not happening

Front 38

these two salt preparations of pen G absorb fast IM

Back 38

potassium Pen G

sodium Pen G

Front 39

for syphillis use this slow acting preparation of pen G

Back 39

benzathine

Front 40

immediate penicillin allergic reaction occurs

Back 40

2-30 minutes

Front 41

accelerated Pen G allergic reaction occurs within

Back 41

1-72 hours

Front 42

used to test for Pen G allergies

Back 42

Pre-Pen

Front 43

pen G desensitization schedule

Back 43

small dose, 60 minutes, larger dose, etc

Front 44

delays pen G renal excretion, prolonging effects

Back 44

probenecid

Front 45

oral penicillin prepartion

Back 45

penicillin V

Front 46

two broad spectrum penicillins

Back 46

ampicillin

amoxicillin

Front 47

aminopenicillins (amipicillin and amoxicillin) good for these diseases (4)

Back 47

mirabilis (dirt), e coli, salmonella, influenzae

Front 48

2 extended spectrum penicillins (antipseudomonal)

Back 48

ticarcillin

pipercillin

Front 49

adverse of ticarcillin (2)

Back 49

sodium fluid overload

bleeding

Front 50

pipercillin better than ticarcillin against pseudomonas because

Back 50

less risk of sodium overload

Front 51

one penicillin preparation that you can take with meals

Back 51

augmentin (amoxicillin / clavulanic acid)

Front 52

contact sports at risk for this infection

Back 52

MRSA (skin to skin contact)

Front 53

cephalosporins family

Back 53

beta-lactam ring antibiotic

Front 54

two cephalosporins that cause bleeding

Back 54

cefotetan and ceftriaxone

Front 55

two cephalosporins that don't mix with alcohol

Back 55

cefotetan and cefazolin

Front 56

vancomycin used for (3)

Back 56

c diff, MRSA, penicillin allergy

Front 57

ceftriaxone two interactions (2)

Back 57

calcium in neonates - precipitates

alcohol - disulfiram like reaction

Front 58

this drug that stars with a P delays renal excretion of some cephalosporins and some penicillins

Back 58

probenecid

Front 59

this cephalosporin can affect those with milk allergy

Back 59

cefditoren

Front 60

cephalosporins can promote this disease

Back 60

C Diff

Front 61

vancomycin for (3)

Back 61

MRSA, C diff, and penicillin allergic

Front 62

indications of antimicrobial effects (5)

Back 62

reduced fever, pain, inflammation; improved appetite, decreased diarrhea

Front 63

vancomycin serum levels

Back 63

15-20 mcg/mL

Front 64

red man syndrome

Back 64

from rapid vancomycin infusion

Front 65

vancomycin biggest adverse

Back 65

renal failure

Front 66

infuse vancomycin over at least ___________ minutes

Back 66

60 minutes

Front 67

imipenem is

Back 67

carbapenem antibiotic

Front 68

imipenem spectrum is

Back 68

broadest

Front 69

imipenem not work on

Back 69

MRSA

Front 70

imipenem supplied in doses combined with

Back 70

cilastatin to prevent destruction by renal enzymes

Front 71

imipenem interaction with ______

Back 71

valproate may cause breakthrough seizures

Front 72

when using imipenem on pseudomonas______

Back 72

use other anti pseudomonas to prevent emergence of resistant organism

Front 73

drugs of choice for c diff

Back 73

vancomycin and metronidazole

Front 74

erythromycin action

Back 74

50s ribosomal subunit of bacteria

Front 75

erythromycin __________ effect on bacteria

Back 75

bacteriostatic

Front 76

erythromycin for this conditions (2)

Back 76

whooping cough and diphtheria

Front 77

cardiac adverse of erythromycin

Back 77

QT prolongation

Front 78

erythromycin interactions (6)

Back 78

antidysthrhythmics, CCB, antifungals, HIV meds, carbamazepine for seizures, warfarin

Front 79

clindamycin action

Back 79

acts on bacterial 50s subunit of bacterial ribosome

Front 80

clindamycin adverse

Back 80

C Diff

Front 81

clindamycin use for

Back 81

gangrene, fragilis

Front 82

tetracyclines for these old school diseases (2)

Back 82

ricketts, cholera

Front 83

tetracycline for this std

Back 83

chlamydia

Front 84

tetracyline for this hiking disease

Back 84

lyme disease

Front 85

tetracyline and ulcers?

Back 85

fights pylori

Front 86

tetracycline and mouth?

Back 86

fights gum disease bacteria

Front 87

adverse of tetracyclines (3)

Back 87

bones, c diff, light

Front 88

dont combine tetracyclines with these foods (4)

Back 88

milk, iron, magnesium, antacids

Front 89

tetracycline spectrum

Back 89

broad

Front 90

this antibiotic can supress MRSA and VRE

Back 90

linezolid

Front 91

tetracyclines should be avoided by

Back 91

pregnant women and kids

Front 92

Doxycycline more for (2) than tetracycline

Back 92

Eyes

Malaria