Pharm Lecture 5 General Quesitons Part 1

Front 1

used as continuous analgesic in ICU for compassionate withdrawal

rarely used(iV) for other stuff b/c side effects of.?

Back 1

morphine

hypotension

Front 2

3 uses of morphine

Back 2

increase pain threshold spine

chest pain mi

iv compassionate withdrawal

Front 3

methadone is a synthetic opiod

Back 3

good luck on the exam

whenever that is

Front 4

2 uses of methadone

Back 4

chronic pain states or cancer related pain

controlled withdrawal from other opiod

Front 5

explain methadone kinetics

so be careful giving high dose

Back 5

distributes and accumaltes in tissue

results in slow release in blood stream= long acion

Front 6

methadone has similar potency to which opiod?

longer or shorter duration than that opioD?

Back 6

morphine

longer

Front 7

fentanyl 50 to 100 more potent than this opiod

Back 7

morphine

Front 8

max dosage titrate respone for fentanyl

Back 8

300 mcg

Front 9

2 cautions of fentanyl

Back 9

hypoventilation

avoid on irritable skin

Front 10

which 2 opiods are morphine like?

Back 10

oxycodone

codeine

Front 11

how is codeine an morphine

Back 11

converts/metobolized to morphine

Front 12

route of oxycodone

Back 12

po

Front 13

how is oxycodone a morphine?

Back 13

a synthetic derivative

Front 14

2 uses for buprenorphine

Back 14

opiod detox

moderae sever pain

Front 15

buprenorphine is a partial agonist

briefly explain moa

so partial agonist property leads to less what?

Back 15

se

Front 16

onset of iv naloxone

Back 16

30 sec

Front 17

major se of naloxone

2 of em

Back 17

pulmonary edema

blowout =el bano?

Front 18

2 drugs of phenethrenes(morphine like)

Back 18

morphine

oxycodone

Front 19

3 drugs of phenylpiperidines

Back 19

fentanyl
sufentanyl
meperidine

Front 20

1 drug of diphenylheptane

Back 20

methadone

Front 21

2 atypical opiods

Back 21

tramdaol

tapintadol

Front 22

you want to treat acute pain aggressively

why?

Back 22

so it doesn't progress to chronic

Front 23

trauma/surgery

acute or chronic

Back 23

acute

Front 24

identifiable patholoy

acute or chronic

Back 24

acute

Front 25

short duration

acute or chronic

Back 25

acute

Front 26

predicatble prognosis

acute or chronic

Back 26

acute

Front 27

treatment typically with anaggesics

acute or chronic

Back 27

acute

Front 28

no specific diagnosi

acute or chronic

Back 28

chronic

Front 29

long duration +3 mins

acute or chronic

Back 29

chronic

Front 30

unpredictable prognosi

acute or chronic

Back 30

chronic

Front 31

treatment must be multidisiplinary

acute or chronic

Back 31

chronic

Front 32

usually well localized

somatic vs visceral

Back 32

somatic

Front 33

continous sharp, dull, aching throbbing

somatic vs visceral

Back 33

somatics

Front 34

skin bone joint tisssue

somatic vs visceral

Back 34

somatic

Front 35

poorly localized and often referred pain

somatic vs visceral

Back 35

visceral

Front 36

diffuse, deep, aching, gnawing, vague pressure

somatic vs visceral

Back 36

visceral

Front 37

appendicitis, pancreatitis, colon cancer with lever metastasis

somatic vs visceral

Back 37

visceral

Front 38

read over pathogenisis of pain

Back 38

doo it

Front 39

physiological outcomes of pain

increase or decrease of catabolic demands?

3 disorders?

increase or decrease or bp and hr?

Gi motility?

Back 39

increase cat

thromboembo, pneumonia, atelectasis

increase bp and hr

decrease gi motility

Front 40

numeric rating scale uni or multidimen?

Back 40

unidim scale

Front 41

measure pain intensity and the sensory and behavorial components

more complex

uni or multi

Back 41

multidim scale

Front 42

preferred scale according to Don Jon

an icu non verbal pain scale

Back 42

bps

behavorial pain scale

Front 43

non verbal pain scale

0-2 no pain

3-6 mild pain

7-10 severe pain

check every 4 hrs

Back 43

freebie

Front 44

list 5 who principles

Back 44

CIA PL

give around clock

individualize

adjuvants

po = give orally when possible

use who Ladder

Front 45

name the 3 categories of who step ladder

Back 45

mild

mild moderate

moderate severe

Front 46

who step ladder

mild drugs

Back 46

acetaminophen

ibuprofen

Front 47

who step ladder

mild to moderate

Back 47

codeine

hydrocodone

oxycodone

Front 48

who step ladder

moderate to severe

Back 48

morphine

fentanyl

oxycodone

hydromorphone

Front 49

etiology based approach

for somatic and Visceral(4)

Back 49

nsaids, opiods

tramadol, steroids

Front 50

etiology based approach

for neuropathic(2)

Back 50

anticonvulsant

antidepressants

Front 51

etiology based approach

for neuralgic(3)

Back 51

anticonvulsants

antidepressents

baclofen

Front 52

IV : Epidural : Intrathecal

10 : 1 : .1 rule

Back 52

doubt it will be on exam

Front 53

type of analgesic

effective for mild to moderate pain and bone pain

Back 53

non opiod analgesics

Front 54

do you produce tolerance and dependance with non opiod analgesic like nsaid and acetaminophen?

Back 54

no

Front 55

is there a ceiling analgesic effect for non opiods?

Back 55

yes

Front 56

considered to decreas the amount of opiods administered = non opiods

Back 56

ehh

Front 57

read over opiod analgesic slide

Back 57

don't be lazy

Front 58

opiod receptors are present in (2 places)

Back 58

cns and peripheral tissues

Front 59

read over pain pathways

Back 59

do it