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73 Cards in this Set

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  • Back
Adverse Effects of Drugs
Drug
Penicillin
Hypersensitivity Rx
Hemolytic Anemia
Methicillin
Interstitial Nephritis
Ampicillin Amoxi
Pseudomembranous Colitis
Carbenicillin
Hypersensitivity Rx
Cephalosporin
nephrotoxicity increased w/ Aminoglycosides
Disulfiram-like w/ ethanol
Atreonam
Tx patients w/ renal insufficiency who cannot tolerate aminoglycosides
Imipenem
Seizures
Vancomycin
NOT

Nephrotoxicity
Ototoxicity
Thrombopheblitis

Red man Sx
How do you prevent Red Man Sx?
Antihistamine
Antibiotic causes seizures?
Imipenem
B-lactam that causes nephrotoxicity and disulfiram like?
Cephalosporin
Causes thombophlebitis, nephrotoxicity, ototoxicity?
Vaconmycin
requires O2 for uptake, nephrotoxicity
otoxocitity when combined w/ loops? Teratogen
Aminoglycosides
Fanconi Sx???
Tetracycline
discoloration of teeth and inhibition of bone growth in children?
tetracycline
acute cholestatic hepatitis?

Eosinophilia...
Macrolides
Anemia
Aplastic anemia
Chloramphenicol
Pseudomembranous Colitis
Fever
Diarrhea
Clindamycin
hemolysis G6PD
nephrotoxicity
kernicterus
displaces warfarin from albumin
Sulfonamide
Megaloblastic Anemia
Leukopenia
granulocytopenia
Trimetrophim
Damages cartilage in kids?
Fluoroquinolones
Disulfiram-like?
Metronidazole
Neurotoxicity, acute tubular necrosis
Polymixins
Hemolysis G6PD, neurotoxcity, hepatoxicity?
Isoniazid
anti TB- related to optic neuritis?
Ethambutol

can't see butts..
All TB drugs are?
hepatotoxic
DOC for meningococcus?
Rifampin

less minocycline
Gonorrhea?
Kill with an AX

ceftriAXone
PCP pneunocystis?
TMPX-SMX
Hypotension, fever chills (shake and bake), nephrotoxicity, arrhythmias
Amphoterrible

Amphotericin B
Antifungal
gynecomastia, inhibits p450
fever chills?
-azoles
fluconazole
ketoconazole

the areole grows!
MOA flucytosine?
inhibits DNA
competes w/ uracil
Flucytosine gives you?
flu like
nausea, vomiting diarrhea

bone marrow suppresion
Causes build up of squalene?
Terbinafine
teratogenic
cardiogenic
consufion
increase warfarin metabolism?
fungus drug?
Griseolfulvin
Ataxia, diziness, slurred speech?Pat. w/ parkinson or influenza A?
Amantadine
Delirium, tremor, nephrotoxic?
Acyclovir
Nephrotoxicity in CMV retinits Tx
Foscarnet
If Tx of CMV retinitis Gangciclovir fails?
Foscarnet
Protease Inhibitors?
hyperglycemia
Name a protease inhibitor that causes hyperglycemia, insulin resistance?
saquinavir
ritonavir
indinavir
HIV therapy drug causes pancreatitis?
Didanosine
Zalcitabine
WHat two drugs can't be combiend in HIV therapy?
Didanosine
Zalcitabine
HIV therapy megaloblastic anemia?
AZT
What drug is used for Hep B?
Lamivudine
WHat drug is used for Hep C?
Rivabirin
Dyskinesia?
Levodopa
What epilepsy drug is Liver Fx tests monitoring needed?
Carbamazepine
Neural Tube Deffects in Epilepsy Drug?
Valproate

decreases folate absorption
Epilepsy drug causes sedation, tolerance, dependence?
Benzodiazepines
Epilepsy drug causes diplopia, ataxia, induction of P450
liver toxicity
agranulocytosis?
Carbamazepine
Epiplespy drug causes Steven-Johnson Sx, urticaria, lethargy, headache?
Ethosuximide
Epilepsy drug causes nystagmus, diplopia, ataxia, sedation, gingival hyperplasia, hirsutism, anemia, teratogenic?
phenytoin
Rash, Steven-Johsons Sx?
Lamotrigine
epilepsy drug causes sedation, movement disorder?
gabapentin
epilepsy drug causes mental dulling, sedation, KIDNEY STONES, weight LOSS?
Topiramate
nystagmus, diplopia, lethargy, ataxia, gingival hyperplasia, megaloblastic anemia?
phenytoin
Neuroleptic Malignant Syndrome
Tardive Dyskinesia?
Antipsychotics
What is neuroleptic malignant sx?
rigidity, sweating, hyperpyrexia
anti-pyschotic causes agranulocytosis?
clozapine
what anty-psychotic does NOT cause tardive dyskinesia?
CLozapine
Polyuria (ADH antagonist)
SIADH
RV atrialization?
Lithium
Drug used for Bedwetting?
Imipramine
Drug used for OCD?
clomipramine
Tricyclic cause?
urinary retention
atropine like symptoms
Toxic Effects Tricyclics?
3C
cardiotoxicity
convulsions
coma
What drug causes hallucinations in elderly?
confusion?
Tricyclics
What durg causes hyperthermia, muscle rigidity, cardiovascular collapse?
SSRI mixed with MAO
What drug causes sexual dysfucntion of SSRIs?
sertraline
Antidepressant causes priapism?
Trazodone
What Antidepressant does NOT cause sexual S/E?
bupoprion
Heterocyclic causes sedation, increase cholesterol, increase apetite?
Mirtazapine

aunt Mirta is hungry and high cholestrol only wants to sleep