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73 Cards in this Set
- Front
- Back
Adverse Effects of Drugs
|
Drug
|
|
Penicillin
|
Hypersensitivity Rx
Hemolytic Anemia |
|
Methicillin
|
Interstitial Nephritis
|
|
Ampicillin Amoxi
|
Pseudomembranous Colitis
|
|
Carbenicillin
|
Hypersensitivity Rx
|
|
Cephalosporin
|
nephrotoxicity increased w/ Aminoglycosides
Disulfiram-like w/ ethanol |
|
Atreonam
|
Tx patients w/ renal insufficiency who cannot tolerate aminoglycosides
|
|
Imipenem
|
Seizures
|
|
Vancomycin
|
NOT
Nephrotoxicity Ototoxicity Thrombopheblitis Red man Sx |
|
How do you prevent Red Man Sx?
|
Antihistamine
|
|
Antibiotic causes seizures?
|
Imipenem
|
|
B-lactam that causes nephrotoxicity and disulfiram like?
|
Cephalosporin
|
|
Causes thombophlebitis, nephrotoxicity, ototoxicity?
|
Vaconmycin
|
|
requires O2 for uptake, nephrotoxicity
otoxocitity when combined w/ loops? Teratogen |
Aminoglycosides
|
|
Fanconi Sx???
|
Tetracycline
|
|
discoloration of teeth and inhibition of bone growth in children?
|
tetracycline
|
|
acute cholestatic hepatitis?
Eosinophilia... |
Macrolides
|
|
Anemia
Aplastic anemia |
Chloramphenicol
|
|
Pseudomembranous Colitis
Fever Diarrhea |
Clindamycin
|
|
hemolysis G6PD
nephrotoxicity kernicterus displaces warfarin from albumin |
Sulfonamide
|
|
Megaloblastic Anemia
Leukopenia granulocytopenia |
Trimetrophim
|
|
Damages cartilage in kids?
|
Fluoroquinolones
|
|
Disulfiram-like?
|
Metronidazole
|
|
Neurotoxicity, acute tubular necrosis
|
Polymixins
|
|
Hemolysis G6PD, neurotoxcity, hepatoxicity?
|
Isoniazid
|
|
anti TB- related to optic neuritis?
|
Ethambutol
can't see butts.. |
|
All TB drugs are?
|
hepatotoxic
|
|
DOC for meningococcus?
|
Rifampin
less minocycline |
|
Gonorrhea?
|
Kill with an AX
ceftriAXone |
|
PCP pneunocystis?
|
TMPX-SMX
|
|
Hypotension, fever chills (shake and bake), nephrotoxicity, arrhythmias
|
Amphoterrible
Amphotericin B |
|
Antifungal
gynecomastia, inhibits p450 fever chills? |
-azoles
fluconazole ketoconazole the areole grows! |
|
MOA flucytosine?
|
inhibits DNA
competes w/ uracil |
|
Flucytosine gives you?
|
flu like
nausea, vomiting diarrhea bone marrow suppresion |
|
Causes build up of squalene?
|
Terbinafine
|
|
teratogenic
cardiogenic consufion increase warfarin metabolism? fungus drug? |
Griseolfulvin
|
|
Ataxia, diziness, slurred speech?Pat. w/ parkinson or influenza A?
|
Amantadine
|
|
Delirium, tremor, nephrotoxic?
|
Acyclovir
|
|
Nephrotoxicity in CMV retinits Tx
|
Foscarnet
|
|
If Tx of CMV retinitis Gangciclovir fails?
|
Foscarnet
|
|
Protease Inhibitors?
|
hyperglycemia
|
|
Name a protease inhibitor that causes hyperglycemia, insulin resistance?
|
saquinavir
ritonavir indinavir |
|
HIV therapy drug causes pancreatitis?
|
Didanosine
Zalcitabine |
|
WHat two drugs can't be combiend in HIV therapy?
|
Didanosine
Zalcitabine |
|
HIV therapy megaloblastic anemia?
|
AZT
|
|
What drug is used for Hep B?
|
Lamivudine
|
|
WHat drug is used for Hep C?
|
Rivabirin
|
|
Dyskinesia?
|
Levodopa
|
|
What epilepsy drug is Liver Fx tests monitoring needed?
|
Carbamazepine
|
|
Neural Tube Deffects in Epilepsy Drug?
|
Valproate
decreases folate absorption |
|
Epilepsy drug causes sedation, tolerance, dependence?
|
Benzodiazepines
|
|
Epilepsy drug causes diplopia, ataxia, induction of P450
liver toxicity agranulocytosis? |
Carbamazepine
|
|
Epiplespy drug causes Steven-Johnson Sx, urticaria, lethargy, headache?
|
Ethosuximide
|
|
Epilepsy drug causes nystagmus, diplopia, ataxia, sedation, gingival hyperplasia, hirsutism, anemia, teratogenic?
|
phenytoin
|
|
Rash, Steven-Johsons Sx?
|
Lamotrigine
|
|
epilepsy drug causes sedation, movement disorder?
|
gabapentin
|
|
epilepsy drug causes mental dulling, sedation, KIDNEY STONES, weight LOSS?
|
Topiramate
|
|
nystagmus, diplopia, lethargy, ataxia, gingival hyperplasia, megaloblastic anemia?
|
phenytoin
|
|
Neuroleptic Malignant Syndrome
Tardive Dyskinesia? |
Antipsychotics
|
|
What is neuroleptic malignant sx?
|
rigidity, sweating, hyperpyrexia
|
|
anti-pyschotic causes agranulocytosis?
|
clozapine
|
|
what anty-psychotic does NOT cause tardive dyskinesia?
|
CLozapine
|
|
Polyuria (ADH antagonist)
SIADH RV atrialization? |
Lithium
|
|
Drug used for Bedwetting?
|
Imipramine
|
|
Drug used for OCD?
|
clomipramine
|
|
Tricyclic cause?
|
urinary retention
atropine like symptoms |
|
Toxic Effects Tricyclics?
|
3C
cardiotoxicity convulsions coma |
|
What drug causes hallucinations in elderly?
confusion? |
Tricyclics
|
|
What durg causes hyperthermia, muscle rigidity, cardiovascular collapse?
|
SSRI mixed with MAO
|
|
What drug causes sexual dysfucntion of SSRIs?
|
sertraline
|
|
Antidepressant causes priapism?
|
Trazodone
|
|
What Antidepressant does NOT cause sexual S/E?
|
bupoprion
|
|
Heterocyclic causes sedation, increase cholesterol, increase apetite?
|
Mirtazapine
aunt Mirta is hungry and high cholestrol only wants to sleep |