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67 Cards in this Set
- Front
- Back
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Norepinephrine
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symp agonist Catecholamines
direct a1,a2, catecholamines metabolize fast, don't pass BBB, need to be injected/infused |
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Epinephrine
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symp agonist Catecholamines
direct a1,a2, b1, b2 catecholamines metabolize fast, don't pass BBB, need to be injected/infused |
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Isoproterenol
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symp agonist Catecholamines
direct b1, b2 (thus no vasoconstriction of vessels) catecholamines metabolize fast, don't pass BBB, need to be injected/infused |
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Dopamine
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symp agonist Catecholamines direct a1,b1,b2 & DA receptors (renal vessels dialation)
catecholamines metabolize fast, don't pass BBB, need to be injected/infused |
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Dobutamine
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symp agonist Catecholamines
direct b1, (good for hypertension) catecholamines metabolize fast, don't pass BBB, need to be injected/infused |
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Phenylephrine
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symp agonist NON-Catecholamines
direct a1 non-catecholamines metabolize slower, only Ephedrine and amphetamine pass BBB, bc they have no OH groups |
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Tetrahyrozoline
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symp agonist NON-Catecholamines
direct a1 non-catecholamines metabolize slower, only Ephedrine and amphetamine pass BBB, bc they have no OH groups NOTE- ZOLINE ending = direct a1, non-catech |
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naphazoline
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symp agonist NON-Catecholamines
direct a1 non-catecholamines metabolize slower, only Ephedrine and amphetamine pass BBB, bc they have no OH groups NOTE- ZOLINE ending = direct a1, non-catech |
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oxymetazoline
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symp agonist NON-Catecholamines
direct a1 non-catecholamines metabolize slower, only Ephedrine and amphetamine pass BBB, bc they have no OH groups NOTE- ZOLINE ending = direct a1, non-catech |
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ritodrine
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symp agonist NON-Catecholamines
direct b2>b1 non-catecholamines metabolize slower, only Ephedrine and amphetamine pass BBB, bc they have no OH groups NOTE- -ol ending > b2 non-catecho |
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metaproterenol
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symp agonist NON-Catecholamines
direct b2>b1 non-catecholamines metabolize slower, only Ephedrine and amphetamine pass BBB, bc they have no OH groups NOTE- -ol ending > b2 non-catecho |
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albuterol
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symp agonist NON-Catecholamines
direct b2>b1 non-catecholamines metabolize slower, only Ephedrine and amphetamine pass BBB, bc they have no OH groups NOTE- -ol ending > b2 non-catecho |
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salbutamol
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symp agonist NON-Catecholamines
direct b2>b1 non-catecholamines metabolize slower, only Ephedrine and amphetamine pass BBB, bc they have no OH groups NOTE- -ol ending > b2 non-catecho |
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salmeterol
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symp agonist NON-Catecholamines
direct b2>b1 non-catecholamines metabolize slower, only Ephedrine and amphetamine pass BBB, bc they have no OH groups NOTE- -ol ending > b2 non-catecho |
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formoterol
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symp agonist NON-Catecholamines
direct b2>b1 non-catecholamines metabolize slower, only Ephedrine and amphetamine pass BBB, bc they have no OH groups NOTE- -ol ending > b2 non-catecho |
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terbutaline
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symp agonist NON-Catecholamines
direct b2>b1 non-catecholamines metabolize slower, only Ephedrine and amphetamine pass BBB, bc they have no OH groups NOTE- -ol ending > b2 non-catecho |
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Clonidine
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symp agonist NON-Catecholamines
direct a2 (rx for pancreas) non-catecholamines metabolize slower, only Ephedrine and amphetamine pass BBB, bc they have no OH groups |
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Ephedrine/ pseudoephedrine
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symp agonist NON-Catecholamines
indirect on a & b (releases more) non-catecholamines metabolize slower, only Ephedrine and amphetamine pass BBB, bc they have no OH groups |
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amphetamine
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symp agonist NON-Catecholamines
indirect on a & b (releases more) non-catecholamines metabolize slower, only Ephedrine and amphetamine pass BBB, bc they have no OH groups |
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cocaine
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symp agonist NON-Catecholamines
indirect on a & b (decreases re-uptake) non-catecholamines metabolize slower, only Ephedrine and amphetamine pass BBB, bc they have no OH groups |
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tyramine
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symp agonist NON-Catecholamines
indirect on a & b non-catecholamines metabolize slower, only Ephedrine and amphetamine pass BBB, bc they have no OH groups |
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Bethanechol
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para agonist Synth Ach direct muscarinic
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methacholine
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para agonist Synth Ach direct muscarinic
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carbachol
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para agonist Synth Ach direct muscarinic
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pilocarpine
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para agonist alkaloid direct muscarinic
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muscarine
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para agonist alkaloid direct muscarinic
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edrophonium
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para agonist anticholinesterase, reversible, positive charge,
short acting (minutes) organophosphat compounds are well absorbed by skin (+) charge substances show erratic absorption from GI tract and does not cross BBB |
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physostigmine
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para agonist anticholinesterase reversible, positive charge
longer acting (hours), naturally occuring organophosphat compounds are well absorbed by skin (+) charge substances show erratic absorption from GI tract and does not cross BBB |
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neostigmine
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para agonist anticholinesterase reversible , positive charge
longer acting (hours) organophosphat compounds are well absorbed by skin (+) charge substances show erratic absorption from GI tract and does not cross BBB |
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pyridostigmine
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para agonist anticholinesterase reversible , positive charge
longer acting (hours) organophosphat compounds are well absorbed by skin (+) charge substances show erratic absorption from GI tract and does not cross BBB |
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DFP
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para agonist anticholinesterase irreversible
organophosphat compounds are well absorbed by skin (+) charge substances show erratic absorption from GI tract and does not cross BBB |
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isoflurophate
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para agonist anticholinesterase irreversible,
organophosphat compounds are well absorbed by skin (+) charge substances show erratic absorption from GI tract and does not cross BBB |
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organophosophorous compounds
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para agonist anticholinesterase irreversible,
organophosphat compounds are well absorbed by skin (+) charge substances show erratic absorption from GI tract and does not cross BBB |
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organophosphates
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para agonist anticholinesterase irreversible,
organophosphat compounds are well absorbed by skin (+) charge substances show erratic absorption from GI tract and does not cross BBB |
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pesticides/ nerve gases
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para agonist anticholinesterase irreversible,
organophosphat compounds are well absorbed by skin (+) charge substances show erratic absorption from GI tract and does not cross BBB |
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Acetylcholine
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ganglion agonist (Nicotinic, Nn subtype) parasympathetic
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Nicotine (low dose)
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ganglion agonist (Nicotinic, Nn subtype) parasympathetic
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Trimethaphan
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blockade of ganglion sympathetic
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Nioctine (high dose)
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blockade of ganglion sympathetic
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Prazosin
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adrenergic antagonists a1 clinically most important
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Tamsulosin
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a1 blocker, important clinially
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Phenoxybenzamine
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adrenergic antagonists a1, a2 irreversible, long acting
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Propranolol
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adrenergic antagonists b1, b2 lipid solubility differences determine CNS penetration and effects
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Atenolol
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beta1 blocker, "cardioselectiv" affect beta 2 only at higher dose or in sensitive individuals
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Nadolol
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adrenergic antagonists b1, b2 lipid solubility differences determine CNS penetration and effects, nadolol less lipphilic
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Timolol
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adrenergic antagonists b1, b2 lipid solubility differences determine CNS penetration and effects
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Labetalol
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alpha and beta blocker/// Vasodilator beta blocker, mostly beta blocker
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Pindolol
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beta blocker with intrinsic sympathomimetic activity(partial agonist, blocks or stimulates depending on activity of heart)
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Atropine
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antimuscarinic drugs natural competitive blocker
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Scolpolamine
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antimuscarinic drugs natural competitive blocker
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Tropicamide
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antimuscarinic drugs synthetic competitive blocker, neutral has CNS activity!!!
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Propantheline
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antimuscarinic drugs synthetic competitive blocker, positive charge
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Ipratropium
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antimuscarinic drugs synthetic competitive blocker, positive charge
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Dantrolene
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Neuromuscular blocker
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d-Tubocurarine
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Neuromuscular blocker competitive, nondepolarizing durgs
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Atracurium
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Neuromuscular blocker competitive, nondepolarizing durgs
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mivacuronium
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Neuromuscular blocker competitive, nondepolarizing durgs
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vecuronium
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Neuromuscular blocker competitive, nondepolarizing durgs
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pancuronium
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Neuromuscular blocker competitive, nondepolarizing durgs
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Succinylcholine
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Neuromuscular blocker, desensitizing depolarization agent, acts for online 5 minutes
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Botulinus toxin
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Neuromuscular blocker, acetalcholine release inhibitor, new neuron terminals have to be made to restore function
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Pseudocholinesterase
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Neuromuscular blocker
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Carteolol
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beta blocker with intrinsic sympathomimetic activity(partial agonist, blocks or stimulates depending on activity of heart)
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Metoprolol
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beta1 blocker, "cardioselectiv" affect beta 2 only at higher dose or in sensitive individuals /// beta blockers blcok competitively
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Salute
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published under opord-S=size of the enemy A=activity of enemy units L=location of enemy units U=uniform worn by the enemy T=time of each enemy noted E=equipment used or carried by enemy
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Doxazosin
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a1 blocker, clinically important,
alpha and beta blockers are direct |
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Phentolamine
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a1 and a2 blocker, competitive, and short acting
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