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4 Cards in this Set
- Front
- Back
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Class 1 anti arrhythmic agents - the mechanism - examples - 3 medical uses |
Fast Na+ channel block , these channels reduces conduction velocity ———————————- Drugs that close at open state : Quinidine , Procainamide Drugs that close at inactivated state : Mexiletine , lidocaine
——————————— Treat ventricular arrhythmia Treat wolff-parkinson-white syndrome Increase QT interval |
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Class 2 anti arrhythmic agents - the mechanism - examples - 2 medical uses |
Beta blockers ——————————— Propranolol - esmolol - atenolol ——————————— Prevent recurrence of tachycardia Decrease mortality in patients with myocardial infarction |
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Class 3 anti arrhythmic agents - the mechanism - examples - 2 medical uses |
K+ channels blockers , this delays ré polarization resulting in along QT interval ——————————————— Amiodarone ( mostly class 3 but also has 1 ‘ 2 ‘ 4 activity ) Sotalol ( also beta blocker ) ibutilide ——————————————— Treat W-P-WS Treat ventricular tachycardia and atrial fibrillation (sotalol ) Treat atrial flutter ( ibutilide )
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Class 4 anti arrhythmic agents - the mechanism - examples - 2 medical uses |
Ca+ channel blocker ——————————— Verapamil , Diltiazem ——————————— Reduce ventricular rate in patients with atrial fibrillation |
