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34 Cards in this Set

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  • Back
True or false.
Acute pericarditis is a syndrome.
True
Acute pericarditis is most commonly ____________, self-limited to _________ weeks with what two symptoms and signs?
Idiopathic (viral)
1-3 weeks
Sharp substernal pleuritic positional pain
Pericardial friction rub
What does the ECG of acute pericarditis look like?
ST elevation does not confine to coronary territory, has upward concavity (seems to mimic STEMI sometimes)
ST elevation does not confine to coronary territory, has upward concavity (seems to mimic STEMI sometimes)
What are the two types of pericarditis?
Serous and fibrinous
What are some differences between the two types?
Serous has smoother surface, few neutrophils/lymps/macros usually with effusion of 50-200mL of thin fluid (protein <50% serum level)

Fibrinous has dry, roughened, shaggy, bread ad butter surface, many more neutrophils/lymphs/macros,
Is called serofibrinous if it is with effusion.
What are some causes of serous pericarditis?
Heart failure, lymphatic obstruction by tumor, hypoalbuminemia
What are some causes of fibrinous pericarditis?
Viral myopericarditis, uremia, acute MI, metastatic malignancy, autoimmune
What is shown here?
What is shown here?
Fibrinous pericarditis
What is shown here?
What is shown here?
Fibrinous pericarditis = lower layer of more condensed fibrin a few lymphocytes and macrophages
What are three more pathologic types of pericarditis?
Hemorrhagic
Purulent
Constrictive
What is seen with hemorrhagic pericarditis?
Serous, fibrinous or purulent plus hemorrhage, +/- effusion or exudate with blood added
What is seen with purulent (suppurative) pericarditis?
Red granular surface coated with pus, lots of subsurface neutrophils, up to 500 mL exudate in the pericardium
True or false. These three types (hemorrhagic, purulent, and constrictive) are very rare.
True
What are the two forms that post MI pericarditis can take?
1. Extension of visceral pericarditis to parietal over large transmural infarct (uncommon, <5% of infarctions)

2. Dressler syndrome 2-12 weeks after infarction (probably autoimmune but has become rare).
Patients with what two autoimmune diseases get pericarditis? Percentages?
Lupus (as part of polyserositis with simultaneous pleuritis and peritonitis) and rheumatoid arthritis (30%)
Drug-induced pericarditis occurs with what two drugs?
Procainamide (sometimes as part of polyserositis) and hydralazine
What three diseases is hemorrhagic pericarditis associated with?
1. Metastatic carcinoma
2. Leukemia (thrombocytopenia)
3. Tuberculosis
What are important tests for unexplained pericarditis?
Skin test for tuberculosis and chest x-ray
Describe constrictive pericarditis.
Is it rare? What is it commonly due to?
What is the pathology similar to?
Encasement of the heart in a dense fibrinous or fibrocalcific scar which prevents cardiac hypertrophy or dilatation.

Rare, commonly due to previous purulent or tuberculous pericarditis.
What else is on the differential for constrictive pericarditis?

How do you test for it? What will the test show?

How do you treat it?
Restrictive cardiomyopathy

Echocardiogram, computerized tomography, or MRI --> thickened pericardium

Strip it surgically!
What are the normal pericardial effusion values?
What is the purpose of the effusion?
15-50 mL of thin serous fluid in pericardium to lubricate between pericardial sac and heart
Describe the outcomes of the pericardial effusion changes:

Sudden increase up to 250 mL
Between 250 and 300 mL
Slow increase up to 1 L
OK
Can be fatal
OK
What is shown here?
What is shown here?
Pericardial effusion on ultrasound examination
What are common causes of pericardial effusion?
Viral myopericarditis
Metastatic malignancy
Autoimmune disease
Drug-induced
Renal failure
Bleeding (hemopericardium)
True or false.
Cardiac tamponade is a syndrome.
True
What are some signs of cardiac tamponde?

What will the echocardiogram show?
Jugular venous distention, muffled heart sounds, hypotension, pulses paradoxus

Diastolic collapse of right atrium and right ventricle
What is Swan-Ganz?
Equalization of pressures
What is the treatment of cardiac tamponade?
Pericardiocentisis
Pericardiocentisis
What are cardiac myxomas?
Are they rare? What sex are they more common in?
What part of the heart are they most common in?
Benign gelatinous mesenchymal neoplasms of the endocardium

Rare
More common in females
Most in left atrium
What is shown here?
What is shown here?
Scattered stellate cells with scant cytoplasm in a bluish myxoid ground substance.
What are some symptoms of cardiac myxoma?
Dyspnea +/- orthopnea, cough +/- hemoptysis, fatigue, fever, transience neurological symptoms +/- syncope
What are some signs of cardiac myxoma?
Loud first heart sound, diastolic rumble, diastolic tumor plop, holosystolic murmur
What are some complications of cardiac myxoma?
Intermittent mitral obstruction, embolization (50% of patients, to brain in 50%), MI, sudden death
What is the diagnosis and treatment of cardiac myxoma?
Diagnosis = echocardiogram
Treatment = surgical excision (curative)