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34 Cards in this Set
- Front
- Back
True or false.
Acute pericarditis is a syndrome. |
True
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Acute pericarditis is most commonly ____________, self-limited to _________ weeks with what two symptoms and signs?
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Idiopathic (viral)
1-3 weeks Sharp substernal pleuritic positional pain Pericardial friction rub |
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What does the ECG of acute pericarditis look like?
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ST elevation does not confine to coronary territory, has upward concavity (seems to mimic STEMI sometimes)
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What are the two types of pericarditis?
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Serous and fibrinous
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What are some differences between the two types?
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Serous has smoother surface, few neutrophils/lymps/macros usually with effusion of 50-200mL of thin fluid (protein <50% serum level)
Fibrinous has dry, roughened, shaggy, bread ad butter surface, many more neutrophils/lymphs/macros, Is called serofibrinous if it is with effusion. |
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What are some causes of serous pericarditis?
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Heart failure, lymphatic obstruction by tumor, hypoalbuminemia
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What are some causes of fibrinous pericarditis?
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Viral myopericarditis, uremia, acute MI, metastatic malignancy, autoimmune
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What is shown here?
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Fibrinous pericarditis
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What is shown here?
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Fibrinous pericarditis = lower layer of more condensed fibrin a few lymphocytes and macrophages
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What are three more pathologic types of pericarditis?
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Hemorrhagic
Purulent Constrictive |
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What is seen with hemorrhagic pericarditis?
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Serous, fibrinous or purulent plus hemorrhage, +/- effusion or exudate with blood added
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What is seen with purulent (suppurative) pericarditis?
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Red granular surface coated with pus, lots of subsurface neutrophils, up to 500 mL exudate in the pericardium
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True or false. These three types (hemorrhagic, purulent, and constrictive) are very rare.
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True
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What are the two forms that post MI pericarditis can take?
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1. Extension of visceral pericarditis to parietal over large transmural infarct (uncommon, <5% of infarctions)
2. Dressler syndrome 2-12 weeks after infarction (probably autoimmune but has become rare). |
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Patients with what two autoimmune diseases get pericarditis? Percentages?
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Lupus (as part of polyserositis with simultaneous pleuritis and peritonitis) and rheumatoid arthritis (30%)
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Drug-induced pericarditis occurs with what two drugs?
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Procainamide (sometimes as part of polyserositis) and hydralazine
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What three diseases is hemorrhagic pericarditis associated with?
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1. Metastatic carcinoma
2. Leukemia (thrombocytopenia) 3. Tuberculosis |
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What are important tests for unexplained pericarditis?
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Skin test for tuberculosis and chest x-ray
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Describe constrictive pericarditis.
Is it rare? What is it commonly due to? What is the pathology similar to? |
Encasement of the heart in a dense fibrinous or fibrocalcific scar which prevents cardiac hypertrophy or dilatation.
Rare, commonly due to previous purulent or tuberculous pericarditis. |
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What else is on the differential for constrictive pericarditis?
How do you test for it? What will the test show? How do you treat it? |
Restrictive cardiomyopathy
Echocardiogram, computerized tomography, or MRI --> thickened pericardium Strip it surgically! |
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What are the normal pericardial effusion values?
What is the purpose of the effusion? |
15-50 mL of thin serous fluid in pericardium to lubricate between pericardial sac and heart
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Describe the outcomes of the pericardial effusion changes:
Sudden increase up to 250 mL Between 250 and 300 mL Slow increase up to 1 L |
OK
Can be fatal OK |
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What is shown here?
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Pericardial effusion on ultrasound examination
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What are common causes of pericardial effusion?
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Viral myopericarditis
Metastatic malignancy Autoimmune disease Drug-induced Renal failure Bleeding (hemopericardium) |
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True or false.
Cardiac tamponade is a syndrome. |
True
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What are some signs of cardiac tamponde?
What will the echocardiogram show? |
Jugular venous distention, muffled heart sounds, hypotension, pulses paradoxus
Diastolic collapse of right atrium and right ventricle |
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What is Swan-Ganz?
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Equalization of pressures
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What is the treatment of cardiac tamponade?
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Pericardiocentisis
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What are cardiac myxomas?
Are they rare? What sex are they more common in? What part of the heart are they most common in? |
Benign gelatinous mesenchymal neoplasms of the endocardium
Rare More common in females Most in left atrium |
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What is shown here?
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Scattered stellate cells with scant cytoplasm in a bluish myxoid ground substance.
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What are some symptoms of cardiac myxoma?
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Dyspnea +/- orthopnea, cough +/- hemoptysis, fatigue, fever, transience neurological symptoms +/- syncope
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What are some signs of cardiac myxoma?
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Loud first heart sound, diastolic rumble, diastolic tumor plop, holosystolic murmur
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What are some complications of cardiac myxoma?
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Intermittent mitral obstruction, embolization (50% of patients, to brain in 50%), MI, sudden death
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What is the diagnosis and treatment of cardiac myxoma?
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Diagnosis = echocardiogram
Treatment = surgical excision (curative) |