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5 Cards in this Set

  • Front
  • Back
what is the pathophysiologic defect in the sideroblastic anemias
defect in the mitochondrial portion of heme synthesis
morphological finding in Pearson's syndrome
ringed siderblasts
size of RBCs in Pearson syndrome
macrocytic
Pearson syndrome
refractory sideroblastic anemia with vacuolization of bone marrow precursors and exocrine pancreatic dysfunction
three main clinical features of PNH
intravascular hemolysis
bone marrow failure
tendency to venous thrombosis