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17 Cards in this Set
- Front
- Back
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what shifts the oxygen dissociation curve to the right (increased oxygen release, decreased oxygen affinity)
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increased temp
increased 2,3 DPG increased acid (= decreased pH) |
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what is the source of ATP and 2,3 DPG
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anaerobic gycolysis
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how does parvovirus B19 infection suppress erythropoiesis
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impairs erythroid precursors
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is splenectony curative in pk deficiency
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no hemolysis and gallstone production may persist after splenectomy
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What is the inheritance of triose phosphate isomerase deficiency
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AR
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what is the mode of inheritance of phosphoglycerate deficiency? how does this distinguish it from other glycolytic disorders?
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x linked
others are AR |
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What is the basis of homozygous hereditary persistence of hgb F
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absence of delta chain synthesis
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do maternal anti-lewis antibodies cause hemolytic disease of the newborn?
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no
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what is a hemotologic complication of recluse spider bites
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intravascular hemolysis
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what is a hemotologic complication of thermal burns and envenomization
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acquired spherocytic anemia
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what nutritional deficiency is seen with use of anticonvulsant therapy
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folic acid deficiency
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what supplement is needed in hemolytic anemia associated with intravacular hemolysis
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iron therapy
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what morphological finding is associated with CDA type 2
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multinucleated erthyroblasts
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what gene mutation is associated with the development of secondary leukemia in patients with kostmann syndrome (congenital neutropenia).
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gcsf receptor mutation
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neutropenia is associated with what nutitional deficiencies
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copper
B12 folate |
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what are alder reilly bodies, what are they associated with?
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PMN inclusion bodies
mucopolysaccaroidoses |
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miscellaneous causes of neonatal thrombocytopenia
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occult large vessel or catheter thrombosis
placental vessel hemangiomas or thrombosis hemolytic disease of the newborn |
