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12 Cards in this Set
- Front
- Back
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Binding site of Na+/K+ pump |
alpha domain |
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Tay Sachs disease |
B-hexosaminidase (Hex A) deficiency = build up of GM2 gangliosides in lysosomes = neuronal dysfunction |
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Pemphigus |
Immune system attacks desmosomes
= separation of keratinocytes |
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Structure of collagen fibril |
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Celll division (inc. interphase and checkpoints) |
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Progeria |
Mutation in LMNA gene = abnormal lamin A ("progerin") = unstable nuclear membrane = premature cell death |
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Factors that stimulate and inhibit haematopoeisis |
+ = EPO, GCSF, GMCSF, TPO, IL-3, SCF - = TNF, TGF, IL-6, IL-1, interferons |
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Apoptosis |
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How ribosomes work |
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Philadelphia chromosome |
cABL proto-oncogene + BCR gene = activation of ABL kinase |
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Role of DAG in cell signalling |
activates PKC |
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Hoes does insulin increase glucose uptake? |
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