Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
6 Cards in this Set
- Front
- Back
- 3rd side (hint)
|
Statins
|
1st line dec LDL
Reduce CV events & mortality in 1* & 2* prevention. |
Monitor LFT/AST
C/I: pregnancy |
|
|
Nicotinic Acid
|
2nd line dec LDL
best for inc HDL Reduce CV events in 2* prevention |
Monitor Fasting Lipid Panel, LFT, (CK if sx / use with statin)
C/I: active liver dz, active peptic ulcer / bleeding |
|
|
Bile Acid Sequestrant
|
"Colesevelam" - nonsystemic
Add-on to statin for dec LDL Reduce CV events in 1* prevention |
Monitor Fasting Lipid Panel
C/I: GI obstruction, TG >/= 500 TG (150-499) use w/ statin to minimize risk of inc TG |
|
|
Cholesterol Absorption Inhibitor
|
"Ezetimibe 10mg"
Add-on to statin, dec LDL ~18%, use alone if statin intolerance. |
Monitor Fasting Lipid Panel, LFT (when used with statin)
|
|
|
Fibrates
|
"Gemfibrozil / Fenofibrate"
1st line TG >/= 500 Add-on Statin Reduce CV events in 1* and 2* prevention. |
Monitor Fasting Lipid Panel, LFTs, (CK if sx or w/ statin/niacin)
C/I: gallbladder dz, pre-existing, hepatic dysfn, severe renal impairment. |
|
|
Omega 3 Fatty Acid
|
"Lovaza"
dec TG >/= 500 dec non-HDL (doesn't dec LDL, may even inc it if TG>/= 500) CV benefits |
dec TG: 2-4g daily
dec CV risk: 1g daily caution: DM, bleeding disorder |
