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36 Cards in this Set
- Front
- Back
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congenital disease
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in womb
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sequela
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condition resulting from a disease (ie thickening of arterial walls from HBP)
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pharmacodynamics
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biochemical and physiologic effects of drugs and their mechanisms of action
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dystrophic calcification
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macroscopic, dead or dying tissue
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metastatic calcification
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normal tissue, hypercalcemia
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caspases
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enzymes inside the cell involved in apoptosis: protein and DNA digestion
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protein p53
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tumor supressor protein, can be involved in apoptosis, activated by DNA damage
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caseous necrosis
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tissue death in lungs
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parenteral
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injectible
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cytochrome p450 system
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metabolizes drugs (esp. alcohol) in liver by enzyme induction
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stomatitis
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inflammation of mucous membranes
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superinfection
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destruction of body's normal flora
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blood dyscrasia
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bone marrow suppression
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neuroleptic malignant syndrome
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extrapyramidal symptoms
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teratogenicity
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any drug that causes harm to the embryo
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primary lymphyoid tissue
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thymus, bone marrow
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secondary lymphoid tissue
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encapsulated (spleen, nodes)
Diffuse (tonsils, gut) |
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bradykinin
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pain, inflammation, vasodilation (clotting cascade)
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dysmenorrhea
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menstrual cramps; blocked by NSAIDS (prostaglandin induces cramps)
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pancytopenia
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reduction in all blood cells; aplastic anemia
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megaloblasts
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pernicious anemia; disruption in DNA synthesis in blast cells of bone marrow
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thalassemia
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anemia w/ increased RBC destruction
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chelation therapy
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interacts w/ iron; binds and excretes it; thalassemia
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hapten mechanism
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antibody-mediated anemia, type II hypersensitivity
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atopic
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genetically determined hypersensitivity to common environmental allergen
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rhinitis
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hay fever
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myasthenia gravis
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abs attach to nicotinic cholinergic receptors on motor endplate, compliment destroys them
autoimmune disorder muscle weakness |
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commensal flora
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colonized bacteria that normally do not adversely affect the host
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virulence
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disease producing potential
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sepsis
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bacterial toxins in the blood
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hyaluronidase
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enzymes from bacteria that destroy intercellular matrices
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ectopic hormones
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not hormones, but act like it. secreted by malignant tumors
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cachexia
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wasting away
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tamoxifen
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antineoplastic agent that fights estrogen sensitive breast tumor
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pheochromocytoma
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secreting tumor of adrenal medulla; contraindication of nonselective adrenergic agonists
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cycloplegia
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loss of accommodation
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