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6 Cards in this Set

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anaplasia, meaning and significance
refers to complete lack of differentiation, always malignant
morphologic features of individual cells which indicate loss of normal differentiation
pleomorphism
hyperchromasia (from extra DNA)
increased nucleus/cytoplasm ratio
others: irregular nuc shape, large nucleoli, clumping of chromatin
clinical features of bening tumors
remain localized
mobile, well-delinieated on exam
usually slow growing
clinical features of malignant tumor
potential to metastaxize
fixed, irregular, or ill-defined on exam
often rapidly growing
gross features of benign tumor
well circumscribed, often encapsulated
homogeneous
no necrosis
gross features of malignant tumor
irregular, infiltrative, not encapsulated