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26 Cards in this Set
- Front
- Back
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S. aureus |
exfoliative toxin (SSS) TSST (TSS) heat-stable toxins (food poisoning) |
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S. pyogenes |
erythrogenic toxin (scarlet fever) exotoxin A (TSLS) exotoxin B (nec. fasc.) M protein (antiphagocytic, valve dmg) streptolysin O (hemolytic) capsule (hyaluronic acid) |
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S. agalactiae |
capsule (polysaccharide) |
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S. pneumoniae |
IgA protease capsule (polysaccharide) |
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S. viridans |
dextrans |
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B. anthracis |
lethal factor (endopeptidase for MAPK kinases) edema factor (adenylate cyclase - inhibits immune response) capsule (protein) |
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C. tetani |
tetanus toxin (cleaves SNAREs in Renshaw cells) |
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C. botulinum |
botulism toxin (cleaves SNAREs in NMJ) |
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C. difficile |
exotoxin A (attaches to brush border) exotoxin B (depolymerizes actin) |
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C. perfringens |
alpha-toxin (phospholipase damages cell membranes) |
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C. diphtheriae |
diphtheria toxin (ADP-ribosylates EF-2) |
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N. meningitidis |
IgA protease pili (antigenic variation) LOS capsule (polysaccharide) |
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N. gonorrhoeae |
IgA protease pili (antigenic variation) |
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K. pneumoniae |
capsule |
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Salmonella |
type III secretion system capsule |
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S. sonnei |
shiga toxin (binds 60S ribosome subunit) type III secretion system |
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E. coli |
capsule (K is bad) EHEC: shiga-like toxin (60S) ETEC: heat-stable (increase cGMP) heat-labile (increase cAMP) |
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Y. enterocolitica |
capsule |
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Y. pestis |
yops (inhibit phagocytosis and cytokines) type III secretion system |
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V. cholerae |
cholera toxin (ADP-ribosylates Gs and increase cAMP - efflux of chloride) fimbriae (adhesion) |
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H. pylori |
urease (survival) |
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P. aeruginosa |
capsule exotoxin A (ADP-ribosylates EF-2) |
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P. mirabilis |
urease (stones) |
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B. pertussis |
filamentous hemagglutinin (adhesion) pertussis toxin (ADP-ribosylates Gi, increase cAMP, and disables lymphocyte chemokine receptors) adenylate cyclase toxin (increase cAMP) tracheal toxin (damage ciliated resp. cells) |
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H. influenzae |
capsule |
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M. tuberculosis |
sulfatides (prevent phagolysosome fusion) cord factor (elicit granuloma formation by increasing TNFa) |
