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23 Cards in this Set
- Front
- Back
Four types of tissues in the body |
1. Epithelial 2. Connective 3. Nervous 4. Muscle |
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Of the four types of tissues only two of them are excitable, these are: |
1. Nervous 2. Muscle |
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Types of non-dividing cells |
- Neurons - Skeletal muscle cells - Cardiac muscle cells |
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Cells adapt to the environment by undergoing changes in: |
1. Size 2. Number 3. Cell type |
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Atrophy |
decrease in cell size |
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Hypertrophy |
increase in cell size |
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Hyperplasia |
increase in number of cells |
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Metaplasia |
a reversible change in which one adult cell type is replaced by another adult cell type |
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Metaplasia usually occurs in response to? |
1. Chronic irritation 2. Chronic inflammation |
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Dysplasia |
Deranged cell growth of a specific tissue that results in cells that vary in size, shape, and organization |
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Effect of hypoxia on cells |
Deprives the cell of oxygen and interrupts oxidative metabolism and the generation of adenosine triphosphate |
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Five categories of cellular injury |
1. Injury from physical agents 2. Injury form radiation 3. Chemical injury 4. Injury from biological agents 5. Injury from nutritional imbalances |
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Two pathways for apoptosis to occur: |
1. Extrinsic pathway- dependent and under cellular control. 2. Intrinsic pathway is independent and results from injury. |
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Inflammation is? |
protective response intended to eliminate the initial cause of cell injury, remove the damaged tissue and generate new tissue |
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Cardinal signs of inflammation: |
1. Redness- due to increased blood flow due to histamine release. 2. Swelling- due to increased permeability of blood vessels 3. Heat- due to increased tissue perfusion 4. Pain- due to the effect of prostaglandins |
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Acute inflammation involves two major components: |
1. Vascular phase 2. Cellular phase |
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Vascular stage of inflammation |
- Vasodilation of arterioles and venules in the area - Increased capillary permeability -Increased protein causes more fluid to exit the vascular space causing increasing swelling |
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Cellular stage of inflammation |
- Escape (Diapedesis) - Chemotaxis |
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Histamine causes (2 things) |
1. Histamine causes dilation of arterioles 2. Histamine increases the permeability of venules |
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Prostaglandins do what?? |
1. Induce inflammation 2. Enhance the effects of histamine and other inflammatory mediators. |
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Cells associated with allergic disorders and hypersensitive reactions: |
- Eosinophils - Mast cells - Basophils |
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The three R's of healing |
1. Resolution-minimal damage 2. Regeneration, replacement of damaged or destroyed cells with identical cells 3. Remodeling, scar formation, normal tissue is replaced by connective tissue (scar tissue) |
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Carcinoma |
malignant tumor of the epithelial tissue origin |