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23 Cards in this Set

  • Front
  • Back

Four types of tissues in the body

1. Epithelial


2. Connective


3. Nervous


4. Muscle

Of the four types of tissues only two of them are excitable, these are:

1. Nervous


2. Muscle

Types of non-dividing cells

- Neurons


- Skeletal muscle cells


- Cardiac muscle cells

Cells adapt to the environment by undergoing changes in:

1. Size


2. Number


3. Cell type

Atrophy

decrease in cell size

Hypertrophy

increase in cell size

Hyperplasia

increase in number of cells

Metaplasia

a reversible change in which one adult cell type is replaced by another adult cell type

Metaplasia usually occurs in response to?

1. Chronic irritation


2. Chronic inflammation

Dysplasia

Deranged cell growth of a specific tissue that results in cells that vary in size, shape, and organization

Effect of hypoxia on cells

Deprives the cell of oxygen and interrupts oxidative metabolism and the generation of adenosine triphosphate

Five categories of cellular injury

1. Injury from physical agents


2. Injury form radiation


3. Chemical injury


4. Injury from biological agents


5. Injury from nutritional imbalances

Two pathways for apoptosis to occur:

1. Extrinsic pathway- dependent and under cellular control.


2. Intrinsic pathway is independent and results from injury.

Inflammation is?

protective response intended to eliminate the initial cause of cell injury, remove the damaged tissue and generate new tissue

Cardinal signs of inflammation:

1. Redness- due to increased blood flow due to histamine release.


2. Swelling- due to increased permeability of blood vessels


3. Heat- due to increased tissue perfusion


4. Pain- due to the effect of prostaglandins

Acute inflammation involves two major components:

1. Vascular phase


2. Cellular phase

Vascular stage of inflammation

- Vasodilation of arterioles and venules in the area


- Increased capillary permeability


-Increased protein causes more fluid to exit the vascular space causing increasing swelling

Cellular stage of inflammation

- Escape (Diapedesis)


- Chemotaxis

Histamine causes (2 things)

1. Histamine causes dilation of arterioles


2. Histamine increases the permeability of venules

Prostaglandins do what??

1. Induce inflammation


2. Enhance the effects of histamine and other inflammatory mediators.

Cells associated with allergic disorders and hypersensitive reactions:

- Eosinophils


- Mast cells


- Basophils

The three R's of healing

1. Resolution-minimal damage


2. Regeneration, replacement of damaged or destroyed cells with identical cells


3. Remodeling, scar formation, normal tissue is replaced by connective tissue (scar tissue)

Carcinoma

malignant tumor of the epithelial tissue origin