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52 Cards in this Set
- Front
- Back
Lines of Defense
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2nd 3rd |
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1st line of defense
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-Mechanical Barriers |
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2nd line of defense
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-Chemical barriers -Natural Killer Cells -Inflammation -Phagocytosis -Fever |
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3rd Line of Defense
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-Immunity |
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Body Defenses
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-Injury -Disease |
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Inflammation
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-redness -swelling -warmth -Pain *Possible loss of function |
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4 ORs of Inflammation
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Tumor (swelling) Calor (Warmth) Dolor (pain) |
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Acute Inflammation
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-Damaged cell contents attract leukocytes to the area ("chemotaxis") and the "cellular response" begins -These cells then move through the cell wall into the interstitial space, a process known as "diapedesis" |
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Diapedesis
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Cells move through the cell wall into interstitial space
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Vascular response
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Vasodilation and increased Capillary permeability |
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Cellular Response (Chemotaxis)
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Damaged cell contents attract leukocytes to the area |
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Exudates
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Fibrinous Purulent Hemorrhagic |
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Serous Exudate
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-Consists primarily of fluid with small amounts of protein and white blood cells *Causes -Allergic Reaction -Burns |
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Fibrinous Exudate
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-Increase risk of scar tissue in an area |
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Purulent (pus) Exudate
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*Contains -Leukocytes -Cellular debris -Microorganisms *Indicates -Bacterial infection |
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Hemorrhagic (bloody) Exudate
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May be present if blood vessels have been damaged |
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Healing
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Regeneration Replacement |
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Resolution
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*Cells recover and return to normal in a short period of time -Ex. Sunburn |
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Regeneration
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*Occurs in damaged tissue that can still undergo mitosis *Tissue is replaced by identical tissue from the proliferation of nearby cells *Sometimes the tissue will be altered and may distort orderly arrangement of cells -Ex: Fibrous tissue in the liver nodules of new cells form and do not contribute to the overall function of the liver |
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Replacement (by connective tissue)(scar or fibrous tissue formation)
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*Cells are incapable of mitosis -Ex. Brain or Myocardium |
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Superficial Partial thickness
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*Injuring only the epidermis |
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Deep Partial thickness |
*Destroys epidermis and some of dermis |
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Full Thickness |
*Destroys all skin layers and underlying tissue *Area is -Coagulated or Charred (surface is hard and dry-Eschar) |
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Rule of Nines |
*Posterior head and Neck-4.5 *Anterior Upper Extremities (R/L)-9 *Posterior Upper Extremities (R/L)-9 *Anterior trunk-18 *Posterior trunk-18 *Anterior lower extremities (R/L)-18 *Posterior Lower extremities (R/L)-18 *Perineum-1 =100% |
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Example of Rule of Nines *A woman has burns on anterior surfaces of her right arm, chest and right leg |
Chest=9 Anterior right leg=9 **Percentage of body surface area burned is approximately=22.5% |
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*A child burns on the posterior head, posterior trunk, and posterior arms |
Posterior trunk (back)=18 Posterior arms (R/L) = 9 **Percentage of body surface area burned is approximately =31.5% |
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Mechanical barriers |
1st line of defense-Non specific |
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-Natural Killer Cells -Inflammation -Phagocytosis -Fever |
2nd line of defenses-Non Specific |
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-Immunity |
3rd line of defense- Specific |
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All defenses are designed to overcome |
Disease |
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-Redness -Swelling -Warmth -Pain -Possible loss of function |
|
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Rubor |
Redness |
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Tumor |
Swelling |
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Calor |
Warmth |
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Dolor
|
Pain |
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-Damaged cell contents attract leukocytes to the area ("CHEMOTAXIS") and the "CELLULAR RESPONSE" begins |
Acute Inflammation |
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*Acute Inflammation -These cells then move through the cell wall to the interstitial space, a process known as.... |
Diapedesis |
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*Acute Inflammation -Vasodilation and increased capillary permeability make up the______________ to injury |
Vascular response |
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*Acute Inflammation -Damaged cell contents attract leukocytes to the area (________) and the ___________begins |
--Cellular response |
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Exudates
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*Serous *Fibrinous *Purulent *Hemorrhagic |
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Watery Exudate *Consists primarily of fluid with small amounts of protein and white blood cells -Causes -Allergic reactions -Burns |
Serous |
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Exudate *Thick and sticky with a high cell and fibrin content *Increases risk of scar tissue in an area |
Fibrinous |
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*Thick, yellow-green in color *Contains -Leukocytes -Cellular debris -Microorganisms *Indicates -Bacterial infection |
Purulent |
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Bloody Exudate *May be present if blood vessels have been damaged |
Hemorrhagic |
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Regeneration Replacement |
Healing |
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*Occurs with minimal tissue damage *Cells recover and return to normal in short period of time -Ex. Sunburn |
Resolution |
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*Tissue is replaced by identical tissue from the proliferation of nearby cells *Sometimes the tissue will be altered and may distort orderly arrangement of cells -Ex. Fibrous tissue in the liver Nodules of new cells form and do not contribute to the overall function of the liver |
Regeneration |
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-By connective tissue (scar or fibrous tissue formation) *Occurs after extensive tissue damage or *Cells are incapable of mitosis -Ex. Brain or Myocardium |
Replacement |
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*First degree burn *Injuring only the epidermis |
Superficial Partial-thickness |
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*Second degree burn *Destroys epidermis and some dermis |
Deep Partial-Thickness |
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*Destroys all skin layers and underlying tissues *Area is -Coagulated or Charred (surface is hard and dry-Eschar) |
Full-thickness |
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*Woman=______ surface area burned *Child= ______surface area burned |
***31.5% |