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15 Cards in this Set
- Front
- Back
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________ refers to a decline in intellectual or cognitive function to a degree where the person can no longer care for his or her own needs.
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dementia
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The cardinal features of AD are ________, _________, and _________.
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failure of recent memory, disorientation, and confusion
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What are the two characteristic microscopic features of Alzheimer disease?
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1. senile or neuritic plaques
2. neurofibrillary tangles |
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What is deposited in the walls of parenchymal and arachnoid blood vessels in 90% of patients with Alzheimer disease.
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amyloid
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What neurotransmitter is implicated in memory functions.
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Ach
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True or false: Treatment of Alzheimer disease has been largely unsuccessful.
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true
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Which genetic disorder is found more frequently in families where there is also higher rates of AD?
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Down syndrome
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Clinical symptoms of _________ include mask-like facial expression, shuffling gait, and a pill-rolling hand tremor.
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Parkinson syndrome
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Parkinson syndrome is referred to as Parkinson disease when it is ________.
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idiopathic
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The brain in Parkinsonism shows depigmentation of the __________ and ________.
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substantia nigra and locus ceruleus
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What is the chief symptom of amyotrophic lateral sclerosis?
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muscle weakness
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True or false: The muscle weakness associated with ALS is unsymmetrical.
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false
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Small, vermiform movements attributed to the irritation of dying neurons are called _________.
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fasciculations
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Where is the lesion of ALS found?
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spinal cord, medulla and cerebral cortex
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The disease process associated with ALS is called
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spinomuscular atrophy
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