Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
47 Cards in this Set
- Front
- Back
Mechanism of action for
-Aspirin- ASA- |
Prevents the formation of a chemical known as thromboxane A2, which causes platelets to clump together, or aggregate, and form plugs that cause obstruction or constriction of small coronary arteries.
|
|
Indications for -Aspirin-
|
-Fever
-Inflammation -Angina -Acute MI |
|
Adverse reactions of -Aspirin-
|
-Anaphylaxis
-Angioedema -Bronchospasm -Bleeding -Stomach irritation -Nausea/vomiting |
|
Contraindications of Aspirin.
|
-GI Bleeding
-Active ulcer disease -Hemorrhagic Stroke -Bleeding disorders -Children w/ chickenpox or flulike symptoms -Known sensitivity |
|
Dosage of Aspirin.
|
MI-
Adult:160-324mg PO Pediatric: 3-5mg/kg/day Pain or Fever- Adult: 324-650mg PO |
|
Mechanism of Action for
-TERBUTALINE- (BRETHINE) |
Stimulates the Beta2 receptor, producing relaxation of bronchial smooth muscle and bronchodilation.
|
|
Indications of
-Terbutaline- |
Prevention and reversal of bronchospasm.
|
|
Adverse Reactions of
-Terbutaline- |
-Cardiac arrhythmias
-Angina -Anxiety -Headache -Tremor -Palpitations -Dizziness |
|
Contraindications of
-Terbutaline- |
-Known sensitivity to sympathomimetics.
-Use with caution in patients with HTN, cardiac disease, cardiac arrhythmias, diabetes, MAOI therapy, pheochromocytoma, thyrotoxicosis, seizure disorder, and elderly. |
|
Doseage: -Terbutaline-
|
Adult:
-0.25mg Sub-Q every 20min for 3 doses. - The usual site for injection is the lateral deltoid. Pediatric: -0.01mg/kg Sub-Q every 20min for 3doses |
|
Mechanism of Action:
-Racemic Epinephrine- |
Stimulates both alpha and beta receptors, causing vasoconstriction, reduced mucosal edema, and bronchodilation.
|
|
INDICATIONS:
-Racemic Epinephrine- |
-Bronchial asthma
-Croup |
|
ADVERSE REACTIONS:
-Racemic Epinephrine- |
-Anxiety
-Dizziness -Headache -Tremor -Palpations -Tachycardia -Cardiac arrhythmias -Hypertension -Nausea/vomiting |
|
CONTRAINDICATIONS:
-Racemic Epinephrine- |
-Glaucoma
-Elderly -Cardiac disease -Hypertension -Thyroid disease -Diabetes -Known sensitivity to sulfites. |
|
DOSAGE:
-Racemic Epinephrine- |
Adult:
-Add 0.5ml to neb, jet neb-add 3ml. Pediatric: > 4: Same as adult. < 4: none |
|
MOA:
-Albuterol/Ipratropium (Combivent)- |
Binds and stimulates beta2 receptors, resulting in relaxation of bronchial smooth muscle, and antagoinzes the acetylcholine receptor, producing brochodialation,
|
|
INDICATIONS:
-Albuterol/Ipratropium (Combivent)- |
-2nd line Tx in COPD or severe acute asthma exacerbation during medical transport.
|
|
ADVERSE REACTIONS:
-Albuterol/Ipratropium (Combivent) |
-Headache
-Cough -Nausea -Arrhythmias -Paradoxical acute bronchospam |
|
CONTRAINDICATIONS:
-Albuterol/Ipratropium (Combivent) |
-Allergy to soybeans or peanuts.
-Known sensitivity to atropine, albuterol, or thier respective derivatives -Used with caution in patients with asthma, HTN, angina, cardiac arrhythmias, tachycardia, CVD, congenital lon QT syndrome, closed-angle glaucoma. |
|
DOSAGE:
-Albuterol/Ipratropium (Combivent) |
Adult:
-2 puffs inhaled every 6hrs by MDI w/ max 12/day Peds: Not recommended. |
|
MOA; Albuterol
|
Binds and stimulates beta2 receptors, resulting in relaxation of bronchial smooth muscle,
|
|
Indications for albuterol
|
Asthma
Bronchitis COPD |
|
Adverse reactions: albuterol
|
Hyperglycemia
Hypokalemia Palpitations, anxiety, insomnia Sinus Tach Tremor Nausea/vomiting Throat irritation, dry mouth, epistaxis Hypertension Dyspepsia Headache Paradoxical bronchospasm |
|
Contraindications: Albuterol
|
Angioedema
Sensitivity to albuterol or levalbuterol |
|
Doseage: Albuterol
|
Acute Bronchospasm:
Adult: -MDI- 4-8 puffs Q1-4hrs -Neb- 2.5-5mg Q20min Pedi: MDI >4 2puffs q4-6 hr < admin neb Neb- >12 0.5mg/kg/hr < 12 0.15mg/kg/hr q20min |
|
MOA:
-IPRATROPIUM BROMIDE (ATROVENT) |
Antagonizes the acetylcholine receptor on bronchial smooth muscle, producing brochodilation.
|
|
Adverse reactions:
IPRATROPIUM BROMIDE (ATROVENT) |
-Paradoxical acute bronchospasm
-Cough -Throat irritation -Headache -Dizziness -Dry Mouth -Palpitations |
|
CONTRAINDICATIONS:
IPRATROPIUM BROMIDE (ATROVENT) |
-Closed-angle glaucoma
-Bladder neck obstruction -Prostatic hypertrophy -Known sensitivity, including peanuts or soybeans and atropine or atropine derivatives. |
|
DOSAGE:
IPRATROPIUM BROMIDE (ATROVENT) |
Neb:
Adult: 0.5mg q6-8hrs Pedi: 5yr-14yr: 0.25-0.5mg q20min for 3 doses. MDI: Adult:4 puffs q10min no more than 24 puffs/24hrs Pedi: >12: 2-3 puffs q6-8 hr < 5-12yr: 1-2 puffs q6-8hrs |
|
MOA:
ETOMIDATE |
appears to have GABA-like effects.
|
|
INDICATIONS:
ETOMIDATE |
-Induction for RSI and PAI
-Induction of anesthesia. |
|
Adverse Reations:
ETOMIDATE |
-Hypotension
-Respiratory depression -Pain at the site of injection -Temporary involuntary muscle movements -Frequent nausea/vomiting on emergence -Adrenal insufficiency -Hyperventilation -Hypoventilation -Apnea of short duration -Hiccups -Laryngospasm -Snoring -Tachypnea -Hypertension -Cardiac arrhythmias. |
|
Contraindications:
ETOMIDATE |
-Known sensitivity
-Use in pregnancy only if the potential benefits justify the potential risk to the fetus. -Do not use during labor and avoid in nursing mothers. |
|
Dosage:
ETOMIDATE |
Adult:
-0.2-0.6 slow mg/kg IV, IO - typical adult dose is 20mg consider less in elderly or pts with cardiac conditions. Pediatric: -Older than 10: same as adult -Younger than 10 not used. |
|
Classification:
ETOMIDATE |
Sedative/Hypnotic
|
|
Classification:
Acetaminophen |
Analgesic/ Antipyretic
|
|
MOA:
Acetaminophen |
Inhibits prostaglandin synthesis in the central and peripheral nervous system.
Although exact mechanisms are unknown, the antiinflammatory effects are minimal. This drug reduces fever via action in the hypothalamus but is less effective than ibuprofen at reducing fever in children. |
|
Indications:
Acetaminophen |
Mild to moderate pain and commonly used in the tx of fever.
|
|
Adverse Effects:
Acetaminophen |
Overdose is often fatal secondary to liver toxicity and must be treated as a medical emergency.
Blood dyscrasias including hemolytic anemia and renal dysfunction are rare but possible. |
|
Contraindications:
Acetaminophen |
Not to be used with known sensitivity.
|
|
Dosage:
Acetaminophen |
Adults:
-650-1000mg every 4-6 hrs, not to exceed 4000mg/day Pediatric: -<2yrs: not to be used without physicians advice. -2-12yrs: 10-15mg/kg every 4-6hrs, max 50-75mg/kg/day. |
|
Class:
Activated Charcoal. |
Antidote, Adsorbent
|
|
MOA:
Activated Charcoal. |
When certain chemicals and toxins are in proximity to the activated charcoal, the chemical will attach to the surface of the charcoal and become trapped.
|
|
Indications:
Activated Charcoal |
Toxic Ingestion
|
|
Adverse Effects:
Activated Charcoal |
Nausea/vomiting.
Constipation diarrhea if aspirated, can induce a fatal form of pneumonitis |
|
Contraindications:
Activated Charcoal |
Ingestions of:
Acids Alkalis Ethanol Methanol Cyanide Ferrous sulfate or other iron salts. Lithium Coma GI Obstruction |
|
Dosage:
Activated Charcoal |
Adult: 25-100g/dose
Pediatric: 1-2g/kg |