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47 Cards in this Set

  • Front
  • Back
Mechanism of action for
-Aspirin- ASA-
Prevents the formation of a chemical known as thromboxane A2, which causes platelets to clump together, or aggregate, and form plugs that cause obstruction or constriction of small coronary arteries.
Indications for -Aspirin-
-Fever
-Inflammation
-Angina
-Acute MI
Adverse reactions of -Aspirin-
-Anaphylaxis
-Angioedema
-Bronchospasm
-Bleeding
-Stomach irritation
-Nausea/vomiting
Contraindications of Aspirin.
-GI Bleeding
-Active ulcer disease
-Hemorrhagic Stroke
-Bleeding disorders
-Children w/ chickenpox or flulike symptoms
-Known sensitivity
Dosage of Aspirin.
MI-
Adult:160-324mg PO
Pediatric: 3-5mg/kg/day
Pain or Fever-
Adult: 324-650mg PO
Mechanism of Action for
-TERBUTALINE-
(BRETHINE)
Stimulates the Beta2 receptor, producing relaxation of bronchial smooth muscle and bronchodilation.
Indications of
-Terbutaline-
Prevention and reversal of bronchospasm.
Adverse Reactions of
-Terbutaline-
-Cardiac arrhythmias
-Angina
-Anxiety
-Headache
-Tremor
-Palpitations
-Dizziness
Contraindications of
-Terbutaline-
-Known sensitivity to sympathomimetics.
-Use with caution in patients with HTN, cardiac disease, cardiac arrhythmias, diabetes, MAOI therapy, pheochromocytoma, thyrotoxicosis, seizure disorder, and elderly.
Doseage: -Terbutaline-
Adult:
-0.25mg Sub-Q every 20min for 3 doses.
- The usual site for injection is the lateral deltoid.

Pediatric:
-0.01mg/kg Sub-Q every 20min for 3doses
Mechanism of Action:
-Racemic Epinephrine-
Stimulates both alpha and beta receptors, causing vasoconstriction, reduced mucosal edema, and bronchodilation.
INDICATIONS:
-Racemic Epinephrine-
-Bronchial asthma
-Croup
ADVERSE REACTIONS:
-Racemic Epinephrine-
-Anxiety
-Dizziness
-Headache
-Tremor
-Palpations
-Tachycardia
-Cardiac arrhythmias
-Hypertension
-Nausea/vomiting
CONTRAINDICATIONS:
-Racemic Epinephrine-
-Glaucoma
-Elderly
-Cardiac disease
-Hypertension
-Thyroid disease
-Diabetes
-Known sensitivity to sulfites.
DOSAGE:
-Racemic Epinephrine-
Adult:
-Add 0.5ml to neb, jet neb-add 3ml.

Pediatric:
> 4: Same as adult.
< 4: none
MOA:
-Albuterol/Ipratropium (Combivent)-
Binds and stimulates beta2 receptors, resulting in relaxation of bronchial smooth muscle, and antagoinzes the acetylcholine receptor, producing brochodialation,
INDICATIONS:
-Albuterol/Ipratropium (Combivent)-
-2nd line Tx in COPD or severe acute asthma exacerbation during medical transport.
ADVERSE REACTIONS:
-Albuterol/Ipratropium (Combivent)
-Headache
-Cough
-Nausea
-Arrhythmias
-Paradoxical acute bronchospam
CONTRAINDICATIONS:
-Albuterol/Ipratropium (Combivent)
-Allergy to soybeans or peanuts.
-Known sensitivity to atropine, albuterol, or thier respective derivatives
-Used with caution in patients with asthma, HTN, angina, cardiac arrhythmias, tachycardia, CVD, congenital lon QT syndrome, closed-angle glaucoma.
DOSAGE:
-Albuterol/Ipratropium (Combivent)
Adult:
-2 puffs inhaled every 6hrs by MDI w/ max 12/day

Peds:
Not recommended.
MOA; Albuterol
Binds and stimulates beta2 receptors, resulting in relaxation of bronchial smooth muscle,
Indications for albuterol
Asthma
Bronchitis
COPD
Adverse reactions: albuterol
Hyperglycemia
Hypokalemia
Palpitations, anxiety, insomnia
Sinus Tach
Tremor
Nausea/vomiting
Throat irritation, dry mouth, epistaxis
Hypertension
Dyspepsia
Headache
Paradoxical bronchospasm
Contraindications: Albuterol
Angioedema
Sensitivity to albuterol or levalbuterol
Doseage: Albuterol
Acute Bronchospasm:
Adult:
-MDI- 4-8 puffs Q1-4hrs
-Neb- 2.5-5mg Q20min
Pedi:
MDI >4 2puffs q4-6 hr
< admin neb
Neb- >12 0.5mg/kg/hr
< 12 0.15mg/kg/hr q20min
MOA:
-IPRATROPIUM BROMIDE (ATROVENT)
Antagonizes the acetylcholine receptor on bronchial smooth muscle, producing brochodilation.
Adverse reactions:
IPRATROPIUM BROMIDE (ATROVENT)
-Paradoxical acute bronchospasm
-Cough
-Throat irritation
-Headache
-Dizziness
-Dry Mouth
-Palpitations
CONTRAINDICATIONS:
IPRATROPIUM BROMIDE (ATROVENT)
-Closed-angle glaucoma
-Bladder neck obstruction
-Prostatic hypertrophy
-Known sensitivity, including peanuts or soybeans and atropine or atropine derivatives.
DOSAGE:
IPRATROPIUM BROMIDE (ATROVENT)
Neb:
Adult: 0.5mg q6-8hrs
Pedi: 5yr-14yr: 0.25-0.5mg q20min for 3 doses.
MDI:
Adult:4 puffs q10min no more than 24 puffs/24hrs
Pedi:
>12: 2-3 puffs q6-8 hr
< 5-12yr: 1-2 puffs q6-8hrs
MOA:
ETOMIDATE
appears to have GABA-like effects.
INDICATIONS:
ETOMIDATE
-Induction for RSI and PAI
-Induction of anesthesia.
Adverse Reations:
ETOMIDATE
-Hypotension
-Respiratory depression
-Pain at the site of injection
-Temporary involuntary muscle movements
-Frequent nausea/vomiting on emergence
-Adrenal insufficiency
-Hyperventilation
-Hypoventilation
-Apnea of short duration
-Hiccups
-Laryngospasm
-Snoring
-Tachypnea
-Hypertension
-Cardiac arrhythmias.
Contraindications:
ETOMIDATE
-Known sensitivity
-Use in pregnancy only if the potential benefits justify the potential risk to the fetus.
-Do not use during labor and avoid in nursing mothers.
Dosage:
ETOMIDATE
Adult:
-0.2-0.6 slow mg/kg IV, IO
- typical adult dose is 20mg consider less in elderly or pts with cardiac conditions.
Pediatric:
-Older than 10: same as adult
-Younger than 10 not used.
Classification:
ETOMIDATE
Sedative/Hypnotic
Classification:
Acetaminophen
Analgesic/ Antipyretic
MOA:
Acetaminophen
Inhibits prostaglandin synthesis in the central and peripheral nervous system.
Although exact mechanisms are unknown, the antiinflammatory effects are minimal.
This drug reduces fever via action in the hypothalamus but is less effective than ibuprofen at reducing fever in children.
Indications:
Acetaminophen
Mild to moderate pain and commonly used in the tx of fever.
Adverse Effects:
Acetaminophen
Overdose is often fatal secondary to liver toxicity and must be treated as a medical emergency.
Blood dyscrasias including hemolytic anemia and renal dysfunction are rare but possible.
Contraindications:
Acetaminophen
Not to be used with known sensitivity.
Dosage:
Acetaminophen
Adults:
-650-1000mg every 4-6 hrs, not to exceed 4000mg/day

Pediatric:
-<2yrs: not to be used without physicians advice.
-2-12yrs: 10-15mg/kg every 4-6hrs, max 50-75mg/kg/day.
Class:
Activated Charcoal.
Antidote, Adsorbent
MOA:
Activated Charcoal.
When certain chemicals and toxins are in proximity to the activated charcoal, the chemical will attach to the surface of the charcoal and become trapped.
Indications:
Activated Charcoal
Toxic Ingestion
Adverse Effects:
Activated Charcoal
Nausea/vomiting.
Constipation
diarrhea
if aspirated, can induce a fatal form of pneumonitis
Contraindications:
Activated Charcoal
Ingestions of:
Acids
Alkalis
Ethanol
Methanol
Cyanide
Ferrous sulfate or other iron salts.
Lithium
Coma
GI Obstruction
Dosage:
Activated Charcoal
Adult: 25-100g/dose
Pediatric: 1-2g/kg