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21 Cards in this Set

  • Front
  • Back

Distention of enruptured graafian follicle. May be associated with hyperestrogenism and endometrial hyperplasia. Most common ovarian mass in young women.

Follicular cyst

Hemorrhage into persistent corpus luteum. Common regresses spontaneously.

Corpus luteum cyst

Often bilateral-multiple. Due to gonadotropin stimulation. Associated with choriocarcinoma and moles.

Theca-lutein cyst

Blood vessel rupture in cyst wall. Cyst grows with increased blood retention; usually self-resolves.

Hemorrhagic cyst

Mature teratoma. Cystic growths filled with various types of tissue such as fat, hair, teeth, bits of bone, and cartilage.

Dermoid cyst

Endometriosis within ovary with cyst formation. Varies with menstrual cycle. When filled with dark, reddish-brown blood it is called a chocolate cyst.

Endometrioid cyst

Most common ovarian neoplasm. Thin-walled, uni- or multilocular. Lined with fallopian-like epithelium. Often bilateral.

Serous cystadenoma

Multiloculated, large. Lined by mucus-secreting epithelium.

Mucinous cystadenoma

Mass arising from growth of ectopic endometrial tissue. Complex mass on ultrasound. Presents with pelvic pain, dysmenorrhea, dyspareunia.

Endometrioma

Germ cell tumor, most common ovarian tumor in women 20-30 years old. Can contain elements from all 3 germ layers; teeth, hair, sebum are common components. Can present with pain secondary to ovarian enlargement or torsion. Can also contain functional thyroid tissue and present as hyperthyroidism (struma ovarii)

Mature cystic teratoma (dermoid cyst)

Looks like bladder. Solid tumor that is pale yellow-tan color and appears encapsulated. Coffee bean nuclei on H&E.

Brenner tumor

Bundles of spindle-shaped fibroblasts. Meigs syndrome -- triad of ovarian fibroma, ascites, and hydrothorax. Pulling sensation in groin.

Fibromas

Like granulosa cell tumor, may produce estrogen. Usually present as abnormal uterine bleeding in a postmenopausal woman.

Thecoma

Aggressive, contains fetal tissue, neuroectoderm. Immature teratoma is most likely represented by immature/embryonic-like neural tissue. Mature teratoma are more likely to contain thyroid tissue.

Immature teratoma

Most common sex cord stromal tumor. Predominantly women in their 50s. Often produce estrogen and/or progesterone and present with abnormal uterine bleeding, sexual precocity (in pre-adolescents), breast tenderness. Histology shows Call-Exner bodies (resemble primordial follicles)

Granulosa cell tumor

Most common ovarian neoplasm, frequently bilateral. Psammoma bodies.

Serous cystadenocarcinoma

Pseudomyxoma peritonei-intraperitoneal accumulation of mucinous material from ovarian or appendiceal tumor.

Mucinous cystadenocarcinoma

Most common in adolescents. Equivalent to male seminoma but rarer. 1% of all ovarian tumors; 30% of germ cell tumors. Sheets of uniform "fried egg" cells. hCG, LDH = tumor markers.

Dysgerminoma

Rare; can develop during or after pregnancy in mother or baby. Malignancy of trophoblastic tissue (cytotrophoblasts, syncytiotrophoblasts); no chorionic villi present. Increased frequency of theca-lutein cysts. Present with abnormal B-hCG, shortness of breath, hemoptysis. Hematogenous spread to lungs. Very responsive to chemotherapy.

Choriocarcinoma

Aggressive, in ovaries and testes (boys) and sacrococcygeal area in young children. Mot common tumor in male infants. Yellow, friable (hemorrhagic), solid mass. 50% have Schiller-Duval bodies (resemble glomeruli). AFP = tumor marker.

Yolk sac (endodermal sinus) tumor

GI malignancy that metastasizes to the ovaries, causing a mucin-secreting signet cell adenocarcinoma.

Krukenberg tumor