Oral Pathology #17 - Oral Manifestations Of Systemic Diseases

Front 1

Deposition of an extracellular proteinaceous material

Back 1

Amyloidosis

Front 2

Type of amyloidosis associated with:
Older adults
petechia and ecchymoses
macroglossia
xerostomia

Back 2

Primary and myeloma

Front 3

Type of amyloidosis:
-deposits in joints and bones
-carpel tunnel syndrome and cervical spine pain
-tonge associated

Back 3

Hemodialysis associated

Front 4

Congo red and crystal violet stains for what disease?

Back 4

Amyloidosis

Front 5

This disease requires serum electrophoresis to determine whether a monoclonal gammopathy exists so multiple myeloma can be ruled out.

Back 5

Amyloidosis

Front 6

Prognosis in amyloidosis

Back 6

Cutaenous form no impact on survival
Systemic form death from cardiac and renal failure

Front 7

-In infancy may result in blindness and later in life night blindness
-Dryness of skin and conjunctiva with ulceration may progress to blindness

Back 7

Vitamin A Deficiency

Front 8

Thiamin is which vitamin?

Back 8

Vitamin B1

Front 9

Alcoholics and people from southeast asia are commonly deficient in what vitamin?

Back 9

Vitamin B1 (Thiamin)

Front 10

Deficiency in this vitamin can cause cardiovascular and neurologic problems.

Back 10

Vitamin B1 (Thiamin)

Front 11

Cluster of symptoms caused primary by a nutritional defect in Vitamin B1

Back 11

Beriberi

Front 12

Riboflavin is which vitamin?

Back 12

Vitamin B2

Front 13

Deficiency results in glossitis, angular cheilitis, sore throat and swelling and erythema of the oral mucosa

Back 13

Vitamin B2 (Riboflavin)

Front 14

Atrophic glossitis is related to:

Back 14

Vitamin deficiency
anemia
malabsorption
antibiotics

Front 15

Niacin is which vitamin?

Back 15

Vitamin B3

Front 16

An inability to absorb niacin (Vitamin B3) may cause what disease?

Back 16

Pellagra

Front 17

Triad for pellegra

Back 17

Dermatitis
dementia
diarrhea

Front 18

Scurvy is associated with which vitamin?

Back 18

Vitamin C

Front 19

Osteomalacia is associated with which Vitamin?

Back 19

Vitamin D

Front 20

Irritability, growth retardation and prominence of costochondral junctions are descriptive of what?

Bowing of legs

Back 20

Rickets - vitamin D Deficiency

Front 21

Enlargement of costochondral junction due to Vitamin D Deficiency is called?

Back 21

Rachitic Rosery

Front 22

Deficiency in this vitamin causes blood coagulopathy resulting in gingival bleeding

Back 22

Vitamin K

Front 23

Anemia is most commonly caused by a deficiency in: (3)

Back 23

Iron
Folic Acid
B12

Front 24

Hypochromic microcytic RBCs in addition to reduced numbers is suggestive of what?

Back 24

Iron deficiency anemia

Front 25

IDA in conjunction with glossitis and dysphagia
Associated with oral and esophageal SCCa

Back 25

Plummer-Vinson Syndrome

Front 26

Dysphagia
Esophageal webs
Koilonychea (spoon shaped nails)
Hypochromic microcytic anemia

Back 26

Plummer-Vinson Syndrome

Front 27

Megablastic anemia caused by poor absorption of cobalamin (V-B12, extrinsic factor)

Back 27

Pernicious Anemia

Front 28

Either diminished production of growth hormone or reduced capacity of the tissues to respond to growth hormone
Shorter than normal; body proportions appropriate

Back 28

Pituitary Dwarfism

Front 29

Excess hormone production by anterior pituitary gland
Pituitary adenomas produce excess growth hormone

Back 29

Hyperpituitarism

Front 30

Excess production of growth hormone after closure of epiphyseal plates
Pituitary adenoma

Back 30

Acromegaly
if its before the closure of the plates its called gigantism

Front 31

Hypothyroidism in children

Back 31

Cretinism

Front 32

Hypothyroidism in adults

Back 32

Myxedema

Front 33

Hypothyroidism
Primary form: problem with what organ?
Secondary form: problem with what organ?

Back 33

Primary form: thyroid gland abnormal
Secondary: pituitary gland does not produce enough TSH

Front 34

Grave's disease is caused by

Back 34

hyperthyroidism

Front 35

Most characteristic finding is exopthalmos due to accumulation of glycosaminoglycans in the retro-orbatal CT

Back 35

Hyperthyroidism - grave's disease

Front 36

Excessive secretion of parathyroid hormone (PTH) by the 4 parathyroid glands

Back 36

Hyperparathyroidism

Front 37

consists of elevated blood calcium (hypercalcemia) and phosphorus (hyperphosphatemia) which create altered bone metabolism

Back 37

Hyperparathyroidism

Front 38

Loss of lamina dura around teeth is characteristic of:

Back 38

hyperparathyrodism

Front 39

Widened PDL is characteristic of:

Back 39

scleroderma

Front 40

Hyperparathyroidism have these 4 clinical manifestations

Back 40

Stones – kidney stones
Bones – bone and joint pain due to excessive calcium mobilization
Groans – GI cramping due to excess calcium absorption
Moans – personality disorders of variable scope, lethargy, coma

Front 41

brown tumors associated with?

Back 41

hyperparathyroidism

Brown tumors are identical to central giant cell granulomas histologically so when a CGCG is found you must work up for hyperparathyroidism

Front 42

Primary adrenal cortical insufficiency – insufficient production of adrenal steroids

Back 42

Addison’s Disease

Front 43

Oral manifestations for addison's disease

Back 43

Brown pigmentation (bronzing) of skin occurs
Melanotic macules can develop on oral mucosa

Front 44

Hypercortisolism also called

Back 44

Cushing’s syndrome

Front 45

“buffalo hump” associated with?

Back 45

Cushings

Front 46

Hereditary decrease in serum alkaline phosphatase important in the calcification of bone and cementum of teeth

Back 46

Hypophosphatsia

Front 47

Lack of cementum or abnormal cementum formation causes premature loss of deciduous anterior teeth. Deciduous molars and permanent teeth are not affected

Back 47

Hypophosphatasia