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7 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Gliclazide, Glipazide (short acting)
Glibenclamide, Gliepiride (long acting) |
Sulfonylureas
Insulin secretagogues |
Hypoglycaemia
N+V Allergy Minor disulfiram-like reactions HA Cardiotoxicity |
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Repaglinide
Nateglanide |
Meglitinides
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Hypoglycameia
URTI Weight gain Bronchitis HA Nausea Diarrhoea Mild hypoglycaemia NO WEIGHT GAIN |
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Rosiglitazones
Pioglitazones |
Thiazolidinediones
Insulin sensitisers Peroxisone proliferator activated receptor gamma |
Fluid retention
Weight gain Anaemia CVD - Rosiglitazone |
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Metformin
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Biguanides
Insulin secretagogue Decr LDL, FFA, TG Incr HDL |
Decrease weight
GIT - discomfort, diarrhoea, metallic taste, anorexia Lactic acidosis |
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Alpha glucosidase (-)
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Acarbose
(-) breakdown CHO in the small intesting |
GIT disturbances
Dose dependent toxicity |
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Vildagliptin
Sitagliptin |
Dipeptidyl peptidase IV (-)
Incretin enhancer / mimetic DPP-IV is an enzyme that breaks down glucagon-like peptide-1 |
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Exenatide
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Incretin mimetic
Incr insulin secretion Decr glucagon secretion |
T1DM
Ketoacidosis Severe renal impairment Pregnancy |
