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12 Cards in this Set
- Front
- Back
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Loestrin Fe and Ortho-Novum |
Combined estrogen/progestrin drugs Lorestrin Fe - 21/7 Ortho-novum - 7/7/7 triphasic |
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Seasonale |
levonorgestrel (323% binding affinity progestrin) and estrogen 84/7 (menstruate 3X/year) |
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Yaz/Yasmin |
Drospirenone (3mg HIGH DOSE) and estrogen Lawsuits - high incidence of thromboembol. and heart problems; anti-mineralicorticoid activity |
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Plan B, Ulipristal, Copper IUD |
Progestin ONLY post-coital contraception!!! *Plan B contains levonorgestrel (1.7 mg HIGH) which is a high binding affinity (323% progestin) *These do NOT prevent ovulation, rather frustrates implantation, fertilization, or endometrial lining formation. |
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NuvaRing |
intravaginal device which release progestrin and estrogen - pretty low doses |
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Ortho Evra |
transdermal patch norelgestromin and ethinyl estradiol *peaks are relatively low, AUC is relatively high! |
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Estrogen positive SE |
Bone strengthening, lipid metabolism (reduce LDL, inc HDL) |
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Estrogen negative SE |
Liver and GI - inhibits bile transport-->nausea Increases plasma proteins - spec those associated with clotting |
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SE of contraceptives |
Nausea, vomiting, headaches, migraine headaches, dizziness, breast tenderness, decreased sex drive, irregular bleeding, hypertension |
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Ethinyl estradiol & Norethindrone |
Estradiol & progesterone with C17 substitution, making compound more bioavailable and giving it a longer half life and decreasing its metabolism. |
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Preoptic Nucleus |
synthesis of GnRH |
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micronor/camila, depo-provera (IM), implanon (implant), mirena, paragard (copper IUD) |
progestin-only contraceptives |
