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19 Cards in this Set
- Front
- Back
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What are the 5 symptoms of end of life ?
Rx? |
Pain - Rx opioids
SOB - Rx opioids
Anxiety- Rx midazolam 2mg
N&V - Rx Levomepromazine 2.5mg BD
Secretions - Rx: Buscopan 20mg |
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what is lymphangiitis ?
Rx? |
CA cells accumulate in lymphatics --> SOB
Rx: Steroids |
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What is the WHO pain ladder ? |
1. NSAIDS + Paracetamol (+ gabapentin/amitryptilline)
2. ADD Codeine,tramadol
3. REPLACE w/ Morphine, oxycontin, Fentanyl
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What do you need to give w/ Morphine ? |
Laxative
Antiemetic (metoclopramide 10mg PRN) |
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How do you initiate morphine regime ? |
1. Oramorph 5mg PRN
2. total dosage used over 24 hrs converted to MST BD ( 1/4 of dose in morning & 1/4 at night)
3. Give 1/6th of total dosage used over 24 hrs into oramorph breakthrough PRN |
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How do you Rx neutropenic sepsis ? |
IV Tazobactam + gentamicin |
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For SVC syndrome, describe
S/S Ix Rx |
S/S: Distended veins, plethora, SOB, Oedema
Ix: URGENT CT
Rx: Venoplasty/SVC stent + Dexamethasone |
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For spinal cord compression , how do you
Ix Rx
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Ix: URGENT MRI
Rx: Dexamethasone + radiotherapy |
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Hypercalcemia is seen in which malignancies ? |
SCC
Myeloma
Renal cell carcinoma
Breast ( due to metastasis) |
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How do you Rx hypercalcemia ? |
IV Fluids + bisphosphonates |
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For tumor lysis syndrome , describe
What increases ? Rx Prevention |
Hyperuricemia, Hyperkalemia, hyperphosphatemia , Lactic acidosis
Rx: Haemodialysis
Prevention w/ : Hydrasion + allopurinol/urate oxidase 24 hrs prior to chemo |
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What is urate oxidase/rasburicase ? |
a uricolytic agent |
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For raised ICP w/ malignancy, describe
Ix Rx
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Ix: urgent CT
Rx: Dexamethasone + mannitol
radiotherapy |
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What malignancies secrete ACTH ?
Effect? |
Small cell lung CA
Cushings |
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What malignancies secrete ADH?
Effect? |
Small celll lung CA
Hyponatremia |
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What malignancies secrete antibodies against CA channels @ pre-synaptic NMJ
Effect? |
Small cell lung CA
Lambert eaton syndrome |
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What malignancies secrete PTHrP ?
Effect? |
SCC
Renal cell CA
Breast CA
Myeloma
(Hypercalcemia --> Rx IV fluids + bisphosphonates) |
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What malignancies secrete Calcitriol (Vit D) ?
Effect? |
Hodgkin's lymphoma
other lymphomas
(Hypercalcemia) |
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What malignancies secrete EPO ?
Effect? |
Renal cell CA
Hepatocellular CA |
