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76 Cards in this Set

  • Front
  • Back

COLOBOMA


Defective closure of embryonic fissure


Usually inferior nasal




Manage refractive error


Evaluate for other congenital anomalies


Possible specialized CL



PERSISTENT PUPILLARY MEMBRANE


Most common ocular congenital anomaly


More common in dark eyes (80% of dark eyes, 35% light eyes)


Type 1: Only attached to iris


Type 2: Iridolenticular adhesions




If problematic, YAG laser

HETEROCHROMIA IRIDIS


Unilateral


2 colors, 1 iris




Remove foreign bodies


Manage uveitis

HETEROCHROMIA IRIDUM


Bilateral, different colored irises




Remove foreign bodies


Manage uveitis

RUBEOSIS IRIDES


Neovascularization of iris and angle


Due to ocular ischemia, most commonly diabetic retinopathy






Usually requires PRP


Intra-vitreal anti VEGF (Avastin)



RUBEOSIS IRIDES


Abnormal blood vessels on iris (usually at pupillary margin)






Usually requires PRP


Intra-vitreal anti VEGF (Avastin)



RUBEOSIS IRIDES


Asymptomatic if no angle involvement


Can cause neovascular glaucoma




Usually requires PRP


Intra-vitreal anti VEGF (Avastin)

Aniridia


Abnormal iris development due to genetic mutation


Predisposes patient to Wilm's Tumor (life threatening)


3 classifications (AD, Sporadic, Gillespie Syndrome)



Aniridia


Abnormal iris development due to genetic mutation


Predisposes patient to Wilm's Tumor (life threatening)


3 classifications (AD (66%), Sporadic (33%), Gillespie Syndrome (<1%))

Aniridia


Abnormal iris development due to genetic mutation


Predisposes patient to Wilm's Tumor (life threatening)


3 classifications (AD (66%), Sporadic (33%), Gillespie Syndrome (<1%))

ANIRIDIA


demonstrates MGD


Dry Eye and Limbal stem cell deficiency

ANIRIDIA


75% of cases develop glaucoma


Onset late childhood



ANIRIDIA


Lens subluxation (superiorly), cataract, or aphakia




Often surgical intervention


Artificial pupil


Manage symptoms/conditions (cataract, glaucoma, etc)

ANIRIDIA


Foveal Hypoplasia, ONH hypoplasia, choroidal coloboma




Often surgical intervention


Artificial pupil


Manage symptoms/conditions (cataract, glaucoma, etc)

IRIDOCORNEAL ENDOTHELIAL SYNDROME (ICE)


Unilateral


Middle aged women


Associated with glaucoma (50%)


3 types (Essential Iris Atrophy, Chandler's Syndrome, Cogen Reese Syndrome)




Manage glaucoma


Trabeculoplasty and trabculectomy often unsuccessful


Often requires filtering shunt



ICE - Essential Iris Atrophy


hammered silver endothelium


Progressive severe iris changes



ICE - Chandler's Syndrome


hammered silver endothelium


Mild Iris Changes

ICE- Cogan Reese Syndrome


hammered silver endothelium


Iris nevus syndrome


Iris Atrophy absent in 50% (mild in the rest)


Severe corectopia

ICE


Corneal endothelium flakes off and moves to iris where it blocks outflow = glaucoma (50%)

ICE


may need corneal transplant

ICE


may need corneal transplant

Primary Epithelial Iris Cyst


at pupil border




Argon laser photocoagulation

Primary Epithelial Iris Cyst


at iris root




Argon laser photocoagulation

Primary Stromal Iris Cyst


Onset in 1st years of life




Needle aspiration/Surgical excision


Inject ethanol for 60 seconds to eliminate recurrence


Spontaneous regression has been noted



Secondary Iris Cyst


Implanted: Pearl

Secondary Iris Cyst


Implanted: Serous

Secondary Iris Cyst


Miotic Induced

Secondary Iris Cyst


Parasitic

Brushfield Spots


(associated with Down's Syndrome)

Lisch Nodules


Associated with Neurofibramoatous 1

Inflammatory Nodules


Busacca Nodules


Anterior iris surface

Inflammatory Nodules


Koeppe Nodules


Pupillary border

Iris Nevus


Less than 3mm in diameter

Iris Nevus


Usually inferior

Diffuse Iris Nevus

Iris Nevus Syndrome


(Cogan Reese Syndrome)

Iris Melanoma

Iris Melanoma

Iris Melanoma

Iris Melanoma

Iris Melanoma

Iris Melanoma

Iris Melanoma


Tapioca Melanoma

Iris Melanoma


Diffuse (Loss of crypts of fuch)

Iris Melanoma (Hyphema)

Iris Metastatic Tumor

Iris Metastatic Tumor

Iris Metastatic Tumomr


(Retina looks like breast cancer metastasis - creamy, fluffly, lumpy)












Preseptal cellulitis


Infection anterior to orbital septum


Staph infection, hordeolum, dacryocystitis, sinusitis, URI


NO PROPTOSIS, O.N. PROBLEMS, OR EOM PAIN/HINDERING


Systemic: Augmentin 250-500 mg tid Bactrim in PCN allergy


Topicals dont help much, but would use Vigamox qid


If severe- Admit to hospital- Antibiotic IV: Vancomycin

Preseptal cellulitis


Infection anterior to orbital septum


Staph infection, hordeolum, dacryocystitis, sinusitis, URI


NO PROPTOSIS, O.N. PROBLEMS, OR EOM PAIN/HINDERING




Systemic: Augmentin 250-500 mg tid Bactrim in PCN allergy


Topicals dont help much, but would use Vigamox qid


If severe- Admit to hospital- Antibiotic IV: Vancomycin

Preseptal cellulitis


Infection anterior to orbital septum


Staph infection, hordeolum, dacryocystitis, sinusitis, URI


NO PROPTOSIS, O.N. PROBLEMS, OR EOM PAIN/HINDERING




Systemic: Augmentin 250-500 mg tid


Bactrim in PCN allergy


Topicals dont help much, but would use Vigamox qid


If severe- Admit to hospital- Antibiotic IV: Vancomycin



Orbital cellulitis


Infection posterior to orbital septum (life/sight threatening)


Most commonly from ethmoid sinusitis


Also from Dacrocystitis, dental decay, trauma, orbita surgery, preseptal cellulitis extension




Admit to hospital- IV antibiotics


Monitor ON function every 4 hours


Freq. Fatal with mucormycosis

Orbital cellulitis


Infection posterior to orbital septum (life/sight threatening)


Most commonly from ethmoid sinusitis


Also from Dacrocystitis, dental decay, trauma, orbita surgery, preseptal cellulitis extension




Admit to hospital- IV antibiotics


Monitor ON function every 4 hours


Freq. Fatal with mucormycosis

Orbital cellulitis


Infection posterior to orbital septum (life/sight threatening)


Most commonly from ethmoid sinusitis


Also from Dacrocystitis, dental decay, trauma, orbita surgery, preseptal cellulitis extension




Admit to hospital- IV antibiotics


Monitor ON function every 4 hours


Freq. Fatal with mucormycosis

Orbital cellulitis


Infection posterior to orbital septum (life/sight threatening)


Most commonly from ethmoid sinusitis


Also from Dacrocystitis, dental decay, trauma, orbita surgery, preseptal cellulitis extension




Admit to hospital- IV antibiotics


Monitor ON function every 4 hours


Freq. Fatal with mucormycosis

Orbital cellulitis


Infection posterior to orbital septum (life/sight threatening)


Most commonly from ethmoid sinusitis


Also from Dacrocystitis, dental decay, trauma, orbita surgery, preseptal cellulitis extension




Admit to hospital- IV antibiotics


Monitor ON function every 4 hours


Freq. Fatal with mucormycosis

Orbital cellulitis


Infection posterior to orbital septum (life/sight threatening)


Most commonly from ethmoid sinusitis


Also from Dacrocystitis, dental decay, trauma, orbita surgery, preseptal cellulitis extension




Admit to hospital- IV antibiotics


Monitor ON function every 4 hours


Freq. Fatal with mucormycosis

Orbital cellulitis


Infection posterior to orbital septum (life/sight threatening)


Most commonly from ethmoid sinusitis


Also from Dacrocystitis, dental decay, trauma, orbita surgery, preseptal cellulitis extension




Admit to hospital- IV antibiotics


Monitor ON function every 4 hours


Freq. Fatal with mucormycosis

HSV


>80% of population over 20 infected


< 6% manifest symptoms


2nd most common venereal disease


Leading cause of infectious blindness in US


60% of corneal ulcers in developed countries are due to HSV


10 million ppl with herpetic eye disease

HSV


>80% of population over 20 infected


< 6% manifest symptoms


2nd most common venereal disease


Leading cause of infectious blindness in US


60% of corneal ulcers in developed countries are due to HSV


10 million ppl with herpetic eye disease

HSV 1


Upper body usually


Direct contact transmission

HSV 2


Lower body usually


Sexual and neonatal transmission

HSV - Primary Ocular Infection


94% subclinical


54% blepharoconjunctivitis


63% keratitis

HSV BLEPHAROCONJUCTIVITiS


Periocular Vesicles, Follicular conjunctivitis


Ipsilateral PAL




Drying Agents: Calamine Lotion, Camphor Oil, 70% alcohol


Secondary Infection = Antibiotic ointment


Systemic Antivirals : Acyclovir 400 mg 5x/d 1wk


Valtrex: 1 g 1x/d 1wk


Topical Antivirals: Viroptic 9x/d 1-2 wks


Zirgal gel 5x/d 1-2 wks





HSV BLEPHAROCONJUCTIVITiS


Periocular Vesicles, Follicular conjunctivitis


Ipsilateral PAL




Drying Agents: Calamine Lotion, Camphor Oil, 70% alcohol


Secondary Infection = Antibiotic ointment


Systemic Antivirals : Acyclovir 400 mg 5x/d 1wk Valtrex: 1 g 1x/d 1wk


Topical Antivirals: Viroptic 9x/d 1-2 wks Zirgal gel 5x/d 1-2 wks

HSV KERATITIS


Dendritic ulver with terminal buds

HSV Keratitis




NO STEROIDS


Self resovling, but has a lot of scarring and neo


Cycloplegic: Cyclogyl 1% bid


ATs


Top. Antirvirals: Viroptic 9x/day, Zirgan gel 5x/d


Debridement


Oral Antivirals: Acyclovir 400 mg 5x/day 1-2 wks


Valcyclovir 500 mg tid 1-2 wks





Infectious epithelial keratitis


Looks like primary keratitis


Dendritic pattern preceded by punctate staining

Post-infectious keratitis


Failure for proper re-epithelialization after an ucler has healed




Bandage CL with Antibiotic


Prophylaxis: Vigamox qid


Muro 128


Antivirals generally not needed


Avoid Steroids if possible

Post-infectious keratitis


Failure for proper re-epithelialization after an ucler has healed




Bandage CL with Antibiotic


Prophylaxis: Vigamox qid


Muro 128


Antivirals generally not needed


Avoid Steroids if possible

Interstitial stromal keratitis


Viral replication in the stroma




Cycloplegic: Cyclogyl 1% bid


Top. Steroid: Pred forte qid, long taper


Antivirals: Topical- Viroptic qid, Zirgan tid-qid Oral- Acyclovir 400 mg po bid

Interstitial stromal keratitis


Viral replication in the stroma




Cycloplegic: Cyclogyl 1% bid


Top. Steroid: Pred forte qid, long taper


Antivirals: Topical- Viroptic qid, Zirgan tid-qid Oral- Acyclovir 400 mg po bid

Disciform Stromal Keratitis


HSV infection of corneal endothelium or hypersensitivity to virus




Cycloplegic: Cyclogyl 1% bid


Top. Steroid: Pred forte qid, long taper


Antivirals: Topical- Viroptic qid, Zirgan tid-qid Oral- Acyclovir 400 mg po bid

Disciform Stromal Keratitis


HSV infection of corneal endothelium or hypersensitivity to virus




Cycloplegic: Cyclogyl 1% bid


Top. Steroid: Pred forte qid, long taper


Antivirals: Topical- Viroptic qid, Zirgan tid-qid


Oral- Acyclovir 400 mg po bid



DISCIFORM STROMAL KERATITIS


Wesley's Ring- Antibody/antigen ring surrounding edema

IRIDOCYCLITIS


High IOP due to trabeculitis




Cycloplegic- cyclogyl 1% bid


Topical steroids- Pred Forte qid or q1h




If IOP is high, Timolol 0.5% bid


Antiviral- Viroptic 9x/day, Acyclovir 400 mg 5x/day


NO PROSTAGLANDINS