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What is obesity?

May be defined as an excess of bodyfat (adipose tissue); some body fat is necessary

What does adipose tissue consist of?

Consistsof adipocytes filled with a globule (or globules) of triglyceride such thatthe cytoplasm is pushed to the periphery as is the nucleus (“signet ring”effect)

What does BMI stand for?

Body mass index

How do we calculate BMI?

BMI = weight (kg) / height^2 (m^2)

Is obesity a disease?

Technically yes because it increases morbidity and mortality rates

Risk associated with obesity? (6 points)

-Type 2 diabetes


-Hypertension


-Heart disease


-stroke


-osteoarthritis


-Some cancers

Where is visceral fat located and What is it linked with and why?

-Central/abdominal region


-Strongly linked with diabetes and CVD

Apple

Where is sub-cutaneous fat located?

Peripheral lower-body

Pear

What is Micarber's principle?

Energy Intake>Energy Expenditure

Theory to cause of obesity

Genetic evidence for obesity?

-Twin studies = identical twins raise separately and have similar body weights


-Multiple gene discovered = FTO & MC4R



What protein is linked with the feeling full from food?

Leptin