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30 Cards in this Set
- Front
- Back
Name some fat sources rich in essential fatty acids.
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-Sunflower oil
-Corn oil -Soybean oil |
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What are the differences between omega 6 and omega 3 fatty acids?
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OMEGA 6 FA
-Predominant in terrestrial plants and animals INCLUDES: -Linoleic acid = maintenance of barrier functions of skin -Gamma-linoleic acid = metabolized into anti-inflammatory PG’s -Arachidonic acid = substrate for inflammatory LT’s and PG’s OMEGA 3 FA -Predominates in marine plants and animals INCLUDES: -Alpha-linoleic acid = it is an eicosapentaneoic acid (EPA) and is metabolized by lipooxygenase and cyclooxygenase to LT’s and PG’s |
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Explain why omega 3 fatty acids may be beneficial in decreasing inflammation?
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-EPA metabolized lipooxygenase and cyclooxygenase to LT’s and PG’s (inflammatory mediators)
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Which breed are most commonly affected by vit. A responsive dermatosis?
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Cocker Spaniel
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What are the usual clinical signs for vit. A responsive dermatosis?
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-Thick, inflamed crusty lesions on ventral abdomen and thorax
-Frond-like keratinous plugs adhered to their surface |
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How do you diagnose vit. A responsive dermatosis?
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-Histopath
-Orthokeratotic hyperkeratosis -Follicular keratosis |
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What is panniculitis?
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inflammation of SQ fat
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What is pansteatitis?
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inflammation of fat w/ in abdomen
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What are the DDX for panniculitis and pansteatitis?
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-Bacterial or fungal infection
-Autoimmune disease -Physiochemical problem -Hereditary |
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List 5 diseases which may improve following treatment w/ vit. E.
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1. DLE
2. SLE 3. Epidermolysis bullosa 4. Acanthosis nigricans 5. Demodecosis |
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What breeds are predisoped to zinc responsive dermatosis?
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Syndrome I:
-Siberian Huskies, Bull terriers and Alaskan Malamutes (primarily -Has been reported in Doberman Pinschers and Great Danes Syndrome II: -Great Danes, Doberman Pinschers, GSD, German Shorthair pointers, Standard Poodles |
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What is the characteristic histopathological finding w/ zinc responsive dermatosis?
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Marked diffuse and follicular parakeratotic hyperplasia (seen w/ Syndrome II)
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What are the causes of Syndrome II zinc responsive dermatosis?
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-Over supplementation w/ calcium which causes decreased zinc absorption
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What are the characteristic histopathological findings of generic dog food dermatosis?
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-Focal epidermal necrosis
-Mixed dermal infiltrate -Subacute to chronic dermatitis |
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Understand the concepts of “epidermal turnover time” and “disorder of keratinization”.
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Epidermal Turnover Time:|
-Number of days from stratum basale to stratum corneum -22 days in normal dog -3-5 days in dog w/ a disorder of keratinization Disorder of Keratinization: -Alterations in basal cell mitotic rate -Alterations in transformation of cytoplasmic proteins into keratin -Alterations in exfoliation (may result from changes in epidermal lipids) |
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Outline a diagnostic approach for a dog presenting to your clinic w/ primary complaint of Seborrhea.
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Rule Out:
-Parasites -Infections -Allergies -Irritants -Metabolic disorders -Nutritional disorders -Biopsy skin |
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Know the principle of topical therapy as they relate to the symptomatic control of Seborrhea.
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-Topical therapy is for its antiseborrheic and keratolytic actions
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List indications of use for systemic retinoids and side effects that must be monitored for.
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-Diseases of sebaceous glands (first generation)
-Keratinization disorders (second generation) -Sebaceous adenitis, Mycosis fungoides, Idiopathic seborrhea (third generation) |
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Describe the lesions of feline acne including pathogenesis.
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Lesions:
-Comedones -Papules -Pustules Patho: -Though to be due to improper cleaning of chin -May also be a seborrheic syndrome +/- secondary infection |
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List three breeds w/ an increased incidence of seasonal flank alopecia.
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1. Airedale terriers
2. English bulldogs 3. Boxers |
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List four breeds w/ increased incidence of Alopecia X.
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1. Pomerarians
2. Chow Chows 3. Keeshound 4. Samoyed |
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What treatments would you recommend for acne in a dog?
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-Daily cleansing (Benzoyl peroxide, alcohol, antiseptic shampoos, astringent)
-Local antibiotics (erythromycin or mupiracin) -+/-Systemic antibiotics -+/-Topical Retin A ointment/lotion |
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What treatments would you recommend for acne in a cat?
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-Observe if non-inflammatory
-Clip hair, clean chin (Benzoyl peroxide, alcohol, antiseptic shampoos, astringent) -+/-Local antibiotics and anti-fungals -+/-Systemic antibiotics -+/-Daily cleaning of chin to prevent reoccurence |
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List 2 Keratolytic agents.
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1. Benzoic Acid
2. Vit. A Keratolytic = promotes softening and dissolution of stratum corneum Keratoplastic = normalized epidermal kinetics and keratinization |
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List 2 keratoplastic agents.
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1. Coal Tar
2. Salicylic Acid 3. Sulfur |
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List 2 degreasing agents in medicated shampoos.
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1. Coal Tar
2. Sulfur |
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Describe the clinical findings that may be suggestive of Sertoli cell tumor.
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-Hair loss
-Bone marrow suppression -Fatal thrombocytopenia or anemia -Oily seborrhea -Pruritis -Comedones -Linear prepucial hyperpigmentation -Nipple enlargement |
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List sex hormones produced by the adrenal gland
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-Androgens and Estrogens
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Describe the lesions distribution pattern typical of seasonal flank alopecia.
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-Non-scarring alopecia of thoracolumbar that is bilaterally symmetrical region develops in fall or spring and hair regrows months later
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Describe the lesion distribution pattern typical of Alopecia X.
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-Bilateral symmetrical alopecia
-Dry dull hair coat -Primary hairs lost first -Head and front legs spared |