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30 Cards in this Set

  • Front
  • Back
Name some fat sources rich in essential fatty acids.
-Sunflower oil
-Corn oil
-Soybean oil
What are the differences between omega 6 and omega 3 fatty acids?
-Predominant in terrestrial plants and animals
-Linoleic acid = maintenance of barrier functions of skin
-Gamma-linoleic acid = metabolized into anti-inflammatory PG’s
-Arachidonic acid = substrate for inflammatory LT’s and PG’s

-Predominates in marine plants and animals
-Alpha-linoleic acid = it is an eicosapentaneoic acid (EPA) and is metabolized by lipooxygenase and cyclooxygenase to LT’s and PG’s
Explain why omega 3 fatty acids may be beneficial in decreasing inflammation?
-EPA metabolized lipooxygenase and cyclooxygenase to LT’s and PG’s (inflammatory mediators)
Which breed are most commonly affected by vit. A responsive dermatosis?
Cocker Spaniel
What are the usual clinical signs for vit. A responsive dermatosis?
-Thick, inflamed crusty lesions on ventral abdomen and thorax
-Frond-like keratinous plugs adhered to their surface
How do you diagnose vit. A responsive dermatosis?
-Orthokeratotic hyperkeratosis
-Follicular keratosis
What is panniculitis?
inflammation of SQ fat
What is pansteatitis?
inflammation of fat w/ in abdomen
What are the DDX for panniculitis and pansteatitis?
-Bacterial or fungal infection
-Autoimmune disease
-Physiochemical problem
List 5 diseases which may improve following treatment w/ vit. E.
1. DLE
2. SLE
3. Epidermolysis bullosa
4. Acanthosis nigricans
5. Demodecosis
What breeds are predisoped to zinc responsive dermatosis?
Syndrome I:
-Siberian Huskies, Bull terriers and Alaskan Malamutes (primarily
-Has been reported in Doberman Pinschers and Great Danes
Syndrome II:
-Great Danes, Doberman Pinschers, GSD, German Shorthair pointers, Standard Poodles
What is the characteristic histopathological finding w/ zinc responsive dermatosis?
Marked diffuse and follicular parakeratotic hyperplasia (seen w/ Syndrome II)
What are the causes of Syndrome II zinc responsive dermatosis?
-Over supplementation w/ calcium which causes decreased zinc absorption
What are the characteristic histopathological findings of generic dog food dermatosis?
-Focal epidermal necrosis
-Mixed dermal infiltrate
-Subacute to chronic dermatitis
Understand the concepts of “epidermal turnover time” and “disorder of keratinization”.
Epidermal Turnover Time:|
-Number of days from stratum basale to stratum corneum
-22 days in normal dog
-3-5 days in dog w/ a disorder of keratinization
Disorder of Keratinization:
-Alterations in basal cell mitotic rate
-Alterations in transformation of cytoplasmic proteins into keratin
-Alterations in exfoliation (may result from changes in epidermal lipids)
Outline a diagnostic approach for a dog presenting to your clinic w/ primary complaint of Seborrhea.
Rule Out:
-Metabolic disorders
-Nutritional disorders
-Biopsy skin
Know the principle of topical therapy as they relate to the symptomatic control of Seborrhea.
-Topical therapy is for its antiseborrheic and keratolytic actions
List indications of use for systemic retinoids and side effects that must be monitored for.
-Diseases of sebaceous glands (first generation)
-Keratinization disorders (second generation)
-Sebaceous adenitis, Mycosis fungoides, Idiopathic seborrhea (third generation)
Describe the lesions of feline acne including pathogenesis.
-Though to be due to improper cleaning of chin
-May also be a seborrheic syndrome +/- secondary infection
List three breeds w/ an increased incidence of seasonal flank alopecia.
1. Airedale terriers
2. English bulldogs
3. Boxers
List four breeds w/ increased incidence of Alopecia X.
1. Pomerarians
2. Chow Chows
3. Keeshound
4. Samoyed
What treatments would you recommend for acne in a dog?
-Daily cleansing (Benzoyl peroxide, alcohol, antiseptic shampoos, astringent)
-Local antibiotics (erythromycin or mupiracin)
-+/-Systemic antibiotics
-+/-Topical Retin A ointment/lotion
What treatments would you recommend for acne in a cat?
-Observe if non-inflammatory
-Clip hair, clean chin (Benzoyl peroxide, alcohol, antiseptic shampoos, astringent)
-+/-Local antibiotics and anti-fungals
-+/-Systemic antibiotics
-+/-Daily cleaning of chin to prevent reoccurence
List 2 Keratolytic agents.
1. Benzoic Acid
2. Vit. A
Keratolytic = promotes softening and dissolution of stratum corneum
Keratoplastic = normalized epidermal kinetics and keratinization
List 2 keratoplastic agents.
1. Coal Tar
2. Salicylic Acid
3. Sulfur
List 2 degreasing agents in medicated shampoos.
1. Coal Tar
2. Sulfur
Describe the clinical findings that may be suggestive of Sertoli cell tumor.
-Hair loss
-Bone marrow suppression
-Fatal thrombocytopenia or anemia
-Oily seborrhea
-Linear prepucial hyperpigmentation
-Nipple enlargement
List sex hormones produced by the adrenal gland
-Androgens and Estrogens
Describe the lesions distribution pattern typical of seasonal flank alopecia.
-Non-scarring alopecia of thoracolumbar that is bilaterally symmetrical region develops in fall or spring and hair regrows months later
Describe the lesion distribution pattern typical of Alopecia X.
-Bilateral symmetrical alopecia
-Dry dull hair coat
-Primary hairs lost first
-Head and front legs spared