Nursing Dalhousie Drugs

Front 1

Lidocane

Back 1

Local anasthetic. Blocks sodium channels. Half life extended by epinephrine. SE include tachycardia, bradycardia and palpitations

Front 2

Enkephalin

Back 2

Endrogenous opioid. Brain and adrenyl glands. Stimulates periaqueductal grey matter and Raphe nucleus to activte anagesic pathways

Front 3

Endorphin

Back 3

Endrogenout opioid. Brain and pituitary. Stimulates periaqueductal grey matter and Raphe nucleus to activte anagesic pathways

Front 4

Dysnorphin

Back 4

Endrogenous opioid. Effects opposite of endorphins.

Front 5

Morphine

Back 5

Natural Opioid Agonist. Does not cross BBB. If systolic dips below 90mmHg, stop administration and begin fluid replacement.

Front 6

Codine

Back 6

Natural Opioid Agonist

Front 7

Heroin

Back 7

Semi-Synthetic Opioid Agonist

Front 8

Oxycodone

Back 8

Semi-Synthetic Opioid Agonist

Front 9

Hydromorphone

Back 9

Semi-Synthetic Opioid Agonist

Front 10

Hydrocodone

Back 10

Semi-Synthetic Opioid Agonist

Front 11

Fentanyl

Back 11

Synthetic Opioid Agonist

Front 12

Tramadol

Back 12

Synthetic Opioid Agonist

Front 13

Methadone

Back 13

Synthetic Opioid Agonist. Gives pain relieving effect without the pleasure pathway stimulation.

Front 14

Merpenidine

Back 14

Synthetic Opioid Agonist

Front 15

Buprenophine with Naloxone

Back 15

Synthetic Opioid Agonist-Antagonist. Partial μ agonist, k agonist and d antagonist.

Front 16

Nabuphrine

Back 16

Synthetic Opioid Agonist-Antagonist. K agonist, μ antagonist

Front 17

Pentazocine

Back 17

Synthetic Opioid Agonist-Antagonist. k agonist, weak μ antagonist

Front 18

Naloxone

Back 18

Synthetic Opioid Antagonist

Front 19

Naltrexone

Back 19

Synthetic Opioid Antagonist

Front 20

Methylnaltrexone

Back 20

Synthetic Opioid Antagonist. Will help relieve constapation cause by opioids.

Front 21

Imitrex

Back 21

Serotonin agonist. Triptan. Used to stop migranes by stimulating vasoconstriction in the intercranial blood vessles. SE include vasospasm, vertigo, heavy arms and chest pressure.

Front 22

Ergotamine

Back 22

Seritonin agonist. Used to treat migraines. Supresses the release of CGRP. SE include withdrawal and ergotism (ischemia, cold extremeties, numbness, muscle pain and gangrene.)

Front 23

Amitriptyline

Back 23

Tricyclic Antidepressant. Only antidepressant which helps depression cauaed by Parkinsons Disease.

Front 24

Levodopa

Back 24

Dopamine precurser. Used to help replace dopamine in the striatum of Parkinsons Disease patients. High protein foods decrease absorption.

Hint 24

Also called L-dopa

Front 25

Carbodopa

Back 25

Dopa decarboxylase agonist. Helps to prevent Levodopa from being metabolized in the periphery. Does not cross BBB.

Front 26

Entacapone

Back 26

COMT inhibitor. Increase plasma half life of Levodopa.

Front 27

Pamiprexole

Back 27

Dopamine agonist. Activate dopamine receptors in striatum. SE include nausea, dizziness, insomnia, constipation and hallucinations.

Front 28

Pramiprexole and Levodopa

Back 28

Treats Parkinsons Disease. Can cause orthostatic hypotension, dyskensias and hallucinations.

Front 29

Ropinirole

Back 29

Dopamine agonist. Selective for D2 and De receptors. SE include nausea, insomnia, dizziness, hallucinations and constipation.

Front 30

Apomorphine

Back 30

Dopamine agonist. Non opioid morphine derivative. Used to treat hypomobility in off episodes of Parkinson's

Front 31

Ritigotine

Back 31

Dopamine agaonist. Similar side effects to pramipexole including nausea, dizziness, insomnia, constipation and hallucinations.

Front 32

Selegiline

Back 32

MAO-B inhibitor. Side effects include dizziness, headache, confusion, exacerbation of Levodopa SE.

Front 33

Rasagiline

Back 33

MAO-B inhibitor. SE include arthralgia, dyspepsia, depression, flu like symptoms and Levodopa SE exacerbation.

Front 34

Phenytoin

Back 34

Anticonvulsant. Has many drug interations. Used for partial and tonic-clonic seizures, sodium channel blocker.

Front 35

Carbamazepine

Back 35

Anticonvulsant. Used to treat epilepsy, bipolar and migraines. Supresses high freauency neuronal discharge.

Front 36

Valporic Acid

Back 36

Anticonvulsant. Blocks sodium and calcium channels. May also potentiate GABA.

Front 37

Ethosuximide

Back 37

Anticonvulsant. Used to treat absent seizures.

Front 38

Pregbalin

Back 38

Anticonvulsant. GABA agonist. Expensive and has lots of SE

Front 39

Phenobarbitol

Back 39

Anticonvulsant. Potentiates GABA.

Front 40

Gabapentin

Back 40

Anticonvulsant. Treats partial seizures and used in ajuvant therepy for seizures.

Front 41

Baclofen

Back 41

Antispasmotic and Muscle Relaxant. GABA-B agonist. Supresses hyperactive reflexes in the spinal cord. Withdrawal is a SE.

Front 42

Tizanidine

Back 42

Antispasmotic. Alpha adrenergic agonist. Relieves spasticity. Causes sedation.

Front 43

Diazepam

Back 43

Antispasmotic. GABA-A agonist. Relieves spasticity. SE include sedation, confusion, GI disruption and hypotension.

Front 44

Dantrolene

Back 44

Antispasmotic. Inhibits calcium release in muscles.