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24 Cards in this Set
- Front
- Back
What is delirium?
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Acute, fluctuating change in mental status with inattention and altered level of consciousness.
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What % of delirium is considered hyperactive, hypoactive or a mixture of both?
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Hyperactive (20%)
Hypoactive (30%) Mixed (50%) |
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According to the DSM-IV Diagnostic Criteria, what are the clinical features of delirium?
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Disturbance of consciousness -reduced clarity of awareness of the environment,
reduced ability to focus, sustain, or shift attention; Change in cognition - memory deficit, disorientation, language problem, perceptual disturbance, unexplained by a chronic dementia; Acute onset (hours to days) with fluctuating course throughout the day; Evidence of an illness, trauma, or drug effect. |
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What is agitation?
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Violent motion,
strong or tumultuous emotions. |
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Physical manifestations of agitation?
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Continual movement
Fidgeting - pulling at dressings, catheters, sheets, etc. |
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Cognitive manifestations of agitation?
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Disorientation in one or several spheres
Inability to listen, communicate, or follow commands. |
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True/false?
Agitation frequently equals delirium. |
True
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Name three widely accepted tools used to assess delirium?
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Ramsay Scale
Sedation Agitation Scale Richmond Agitation Sedation Scale (RASS) |
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What is the Confusion Assessment Method for the ICU (CAM-ICU)used for?
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To assess level of delirium
Asess delirium in intubated patients. |
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Reasons delirium remains unrecognized in 66-84% of patients.
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It is often attributed to dementia,depression,“expected”occurrence in critically ill elderly patient;
underdiagnosed when hyperactivity and/or hallucinations not present; it is often not looked for (thought about as a diagnosis). |
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How does pathological changes in the body contribute to delirium?
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Infection and injury resulting in the production of cytokines, cell infiltration, and tissue damage leading to activation of a more systemic response can cause altered patterns of neuronal response that contributes to delirium.
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What are the three primary neurotransmitters of the brain?
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Dopamine, γ-aminobutryic acid (GABA), acetylcholine.
Delirium may be related to imbalances in their synthesis, release, and inactivation. |
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List the three categories of risk factors that predisposes a pt to delirium in the acute care setting?
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Host factors;
Acute illness itself; Iatrogenic or environmental factors. Three or more risk factors increases the likelihood of delirium up to 60%. |
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List three risk factors considered host factors that can cause delirium?
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Age;
Baseline comorbidities; Baseline cognitive impairment. |
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List three iatrogenic or environmental risk factors for delirium?
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Metabolic disturbance, anticholinergic meds, sedative/analgesic meds.
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State two condtion(s)/disease state(s) that are considered risk facors for delirium in the acute care setting?
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Sepsis, hypoxemia.
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What is the global severity of illness score?
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A scoring system that looks at an acute care pt's state of illness to determine the likelihood of developing delirium.
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History of hypertension and smoking have been linked to subsequent development of delirium,specifically how?
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Leads to underperfusion of the brain & nicotine withdrawal.
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Medications are the leading iatrogenic risk factors. List classes of medications that can cause delirium?
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Benzodiazepines,
Anticholinergic, Narcotics & some psychoactive medications. |
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List managemnent stategies for delirium.
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Control behavior,correct underlying insult & rehabilitate.
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How can we minimize iatrogenesis?
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Stop inappropriate medications;
Minimize urinary catheter use; Minimize restraints (actual & perceived). |
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What are "medical housekeeping" measures that can help to prevent delirium?
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CNS oxygen delivery (SpO2 > 95%);
hydration (BUN/creat ratio); attention to electrolytes/glucose; extra vigilance for medical complications. |
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What are rehab measures that can help to prevent delirium?
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Bowel regimen;
Nutrition (extra supplements, TF); Early mobilization; Pain control. |
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Haldol may be used for anti-psychotic therapy in the management of delirium. What is the most adverse effect that this med can cause?
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Increased QT -> TdP
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