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24 Cards in this Set

  • Front
  • Back
What is delirium?
Acute, fluctuating change in mental status with inattention and altered level of consciousness.
What % of delirium is considered hyperactive, hypoactive or a mixture of both?
Hyperactive (20%)
Hypoactive (30%)
Mixed (50%)
According to the DSM-IV Diagnostic Criteria, what are the clinical features of delirium?
Disturbance of consciousness -reduced clarity of awareness of the environment,
reduced ability to focus, sustain, or shift attention;
Change in cognition -
memory deficit, disorientation, language problem, perceptual disturbance,
unexplained by a chronic dementia; 
Acute onset (hours to days) with fluctuating course throughout the day;
Evidence of an illness, trauma, or drug effect.
What is agitation?
Violent motion,
strong or tumultuous emotions.
Physical manifestations of agitation?
Continual movement
Fidgeting - pulling at dressings, catheters, sheets, etc.
Cognitive manifestations of agitation?
Disorientation in one or several spheres
Inability to listen, communicate, or follow commands.
True/false?
Agitation frequently
equals delirium.
True
Name three widely accepted tools used to assess delirium?
Ramsay Scale
Sedation Agitation Scale
Richmond Agitation Sedation Scale (RASS)
What is the Confusion Assessment Method for the ICU (CAM-ICU)used for?
To assess level of delirium
Asess delirium in intubated patients.
Reasons delirium remains unrecognized in 66-84% of patients.
It is often attributed to dementia,depression,“expected”occurrence in critically ill elderly patient;
underdiagnosed when hyperactivity and/or hallucinations not present;
it is often not looked for (thought about as a diagnosis).
How does pathological changes in the body contribute to delirium?
Infection and injury resulting in the production of cytokines, cell infiltration, and tissue damage leading to activation of a more systemic response can cause altered patterns of neuronal response that contributes to delirium.
What are the three primary neurotransmitters of the brain?
Dopamine, γ-aminobutryic acid (GABA), acetylcholine.
Delirium may be related to imbalances in their synthesis, release, and inactivation.
List the three categories of risk factors that predisposes a pt to delirium in the acute care setting?
Host factors;
Acute illness itself;
Iatrogenic or environmental factors.
Three or more risk factors increases the likelihood of delirium up to 60%.
List three risk factors considered host factors that can cause delirium?
Age;
Baseline comorbidities;
Baseline cognitive impairment.
List three iatrogenic or environmental risk factors for delirium?
Metabolic disturbance, anticholinergic meds, sedative/analgesic meds.
State two condtion(s)/disease state(s) that are considered risk facors for delirium in the acute care setting?
Sepsis, hypoxemia.
What is the global severity of illness score?
A scoring system that looks at an acute care pt's state of illness to determine the likelihood of developing delirium.
History of hypertension and smoking have been linked to subsequent development of delirium,specifically how?
Leads to underperfusion of the brain & nicotine withdrawal.
Medications are the leading iatrogenic risk factors. List classes of medications that can cause delirium?
Benzodiazepines,
Anticholinergic,
Narcotics &
some psychoactive medications.
List managemnent stategies for delirium.
Control behavior,correct underlying insult & rehabilitate.
How can we minimize iatrogenesis?
Stop inappropriate medications;
Minimize urinary catheter use;
Minimize restraints (actual & perceived).
What are "medical housekeeping" measures that can help to prevent delirium?
CNS oxygen delivery (SpO2 > 95%);
hydration (BUN/creat ratio);
attention to electrolytes/glucose;
extra vigilance for medical complications.
What are rehab measures that can help to prevent delirium?
Bowel regimen;
Nutrition (extra supplements, TF);
Early mobilization;
Pain control.
Haldol may be used for anti-psychotic therapy in the management of delirium. What is the most adverse effect that this med can cause?
Increased QT -> TdP