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108 Cards in this Set
- Front
- Back
Plavix is approved for?
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Prevention of stroke and MI
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Most common and predictable angina is?
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Stable Angina
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Pt. is most at risk for ____ when they have unstable angina
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Heart Attack
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Atypical, and caused by coronary artery spasm with or without atheroscleroric lesion is _____angina
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Prinzmetals Angina
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Which is more severe? ACS or Angina?
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ACS (acute coronary syndrome)
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This inversion can occur as a result of decreased oxygen
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T-wave inversion
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What EKG abnormality is specific to MI
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ST segment elevation
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What occurs with Pathologic Q-wave? Indicates?
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Q wave is longer than R wave. Indicates past MI
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Which enzymes are SPECIFIC TO CARDIAC MUSCLES?
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CK-MB and Troponin
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Marker that measures for presence of inflammation=
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C-reactive protien
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You're 3x more likely to develop CAD if your total cholesterol is
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>260
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Desirable LDL is
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<130
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Optimal LDL is
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<100
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MD needs to check motion of pt's heart, valve function and EF. What test will he preform?
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Echocardiogram
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Nitrates act on what? to produce what?
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Vascular smooth muscle to produce dilation.
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Explain reflex tachycardia
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As BP drops, our bodies will become
tachy to try and compensate for the low BP |
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How do Beta Blockers help with MI?
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Reduces pain, infarct size, mortality and risk for re-infarction.
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How fast would you expect sub-lingual nitrates to work?
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1-3 minutes
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How do Beta blockers relieve angina?
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Bring O2 demand back in balance with O2 supply
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3 main uses of ACE inhibitors
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Hypertension, heart failure, MI
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Pt. comes in with headache, orthostatic hypotension and reflex tachycardia. You take a look at this meds and realize he is having adverse affects of what medication?
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Nitrates
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Nitrates primarily act on?
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veins
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When is Nitroglycerin used in IV drip?
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Acute MI and perioperative hypertension
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Immediate actions in the ER when a pt comes in with chest pain is?
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M-Morphine Sulfate
O- Oxygen N- Nitroglycerin A- Asa |
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What types of people have the greatest risk of restenosis?
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Diabetics
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Which heart procedure is also called myocardial revascularization?
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CABG (coronary artery bypass graft)
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Name all heart procedures where the heart is beating "off pump"
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MIDCAB (minimally invasive direct cornary bypass graft)
OPCAB (off pump coronary artery bypass) |
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Pt. has too much plaque, it too many arteries, the doctors can do nothing else. The try one last effort to restore O2 to the heart. What will they perform?
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Transmyocardial laser revascularization (TMLR)
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Phase 3 of Cardiac rehab would be?
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At home
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What is considered the "silent disease"
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Hypertension
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What makes hypertension so dangerous?
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Target organ damage
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Which diuretic is the first choice to treat hypertension?
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HCTZ Hydrochlorothiazide
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"Bs" Are Funny...LOL
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Beta Blockers
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Nitrates - Action
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Nitroglycerinst pain
Dilation of arteries and primarily VEINS Acts on vascular smooth muscle = vasodialation decreases cardiac O2 demand slows down venous return to heart |
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Nitrates
Nitroglycerin - 4 types of ingestion |
sublingual: Nitrostat, Nitroquick
transdermal: Nitro-dur, Transderm-Nitro topical ointment: Nitrobid IV: Nitro-bid IIV |
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Isosorbide mononitrate
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Nitroglycerin
Oral tablet IR: ISMO, Monoket Oral Tablet ER: Imdur |
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Isosorbide dinatrate
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Nitroglycerin
Sublingual: Isordil, Sorbitrate Chewable tablets: Sorbitrate Oral tablet IR: Isordil titradose, Sorbitrate Oral Tablet SR:I Isoril Tembids |
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Nitrates
Adverse Effects |
Headache
Orthostatic hypotension Reflex tachycardia |
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Nitrates
Uses |
Angina Pain
Angina Prophylaxis Acute MI and perioperative hypertension (IV) |
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Nitrates
When to go to hospital |
3 doses 5 minutes apart.... if not working...no pain relief...call 911!
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"B's" are Funny...LOL
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Beta Blockers
Anti Hypertensive |
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Beta Blockers... name them
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Inderal (propranolol)
Lopressor (metoprolol) Tenormin (Atenolol) Troprol/Lopressor (metoprolol) Timoptic (timolol) Coreg (carvedilol) Normodyne/Trandate (labetalol) |
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Beta Blockers
Action |
block beta receptors=reduces heart rate, reducing the workload
Reduces force of contraction Reduces speed of conduction thru AV Node |
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Beta Blockers
Used for...? |
Angina
MI CHF (Coreg - carvedilol) Hypertension |
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Beta Blockers
Actions on Angina |
Decrease workload on heart
Evens out supply/demand for O2 - prevents angina pain |
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Beta Blockers
Actions on MI |
Reduces pain, infarct size, mortality
Prevents re-infarction in ER Protects heart from stress hormones & adrenaline |
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Beta Blockers
Actions on CHF |
COREG - (carvedilol)
deb's point! |
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Intermost layer of the heart, thin membrane composed of 3 layers=
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Endocardium
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What is catecholamine?
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Stress hormone stimulated by nicotine
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"Gold standard of heart surgeries"
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CABG
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Stents that are coated with a medication, emits microscopic particles into the artery and helps with plaque. What is this called?
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Drug-eluting stents
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2 reasons pt would need CABG
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Client failed medical management
Advanced disease |
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What nursing consideration should you think about when taking a radial artery and using it for harvesting?
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Test ULNAR artery first! Make sure it works properly, (risky harvest)
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Why is the pt's blooded cooled?
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Cooled blood requires less O2
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Beta Blockers
Caution - Contraindications |
Diabetics - masks symptoms of hypoglycemia
Asthma - can cause bronchospasms or bronchodilation |
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CCB = CCP
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Calcium Channel Blockers
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Calcium Channel Blockers
Name 'em |
Calcium Channel Blockers
Calan ( verapamil) Cardizen (diltiazem) Procardia (nifedipine) |
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Calcium Channel Blockers
Action |
Calcium Channel Blockers
Antihypertensive Block Ca channels in heart Arteriolar dilation = reduced afterload Works on arteries only increase coronary perfusion Reduces HR Decreases Myocardial force of contraction=reduced workload |
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Calcium Channel Blockers
Used for....? |
Stable angina - reduces O2 demand
Prinzmetal angina - reduces arterial spasms Hypertension Cardiac arrhythmia - Cardizem (diltiazem) |
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Calcium Channel Blockers
Which one is used mainly for cardiac arrhythmia? |
Cardizem (diltiazem)
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If you got CHF and Hypertension.... chances are, you're gonna get...
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Beta blockers
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Ace-Pril
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Ace Inhibitors
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Ace Inhibitors
Name 'em |
Ace Inhibitors
Capoten (captopril) Vasotec (enalapril) Zestril or Prinivil (lisnopril) Altace (ramipril) Mavik (trandoalpril) |
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Ace Inhibitors
Action |
Ace Inhibitors
Reduces preload and afterload Promotes H2O lose through kidneys- decreases blood volume ((preload) Prevents or reduce pathologic changes in heart and vessels Dilates vessels - mostly arterial (afterload) |
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Systolic BP > ____ and diastolic > _____ can diagnose hypertension
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>140 and >90
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Pt's BP is 122/84 what BP category are they in?
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Prehypertension
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Ace Inhibitors
Used for? |
Ace Inhibitors
Hypertension - lisinopril CHF - reduces workload on heart MI - reduces mortality, decreases chance of heart failure Neuropathy - diabetic and non-diabetic - slows renal disease Can prevents MI, Stroke, death (Altace - ramipril) |
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Ace Inhibitors
What's up with Altace (ramipril) |
Ace Inhibitors
Reduces mortality in pt with hx of stroke, MI,diabetes and PVD |
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Ace Inhibitors
Adverse Affects |
Ace Inhibitors
First dose hypertension Cough - annoying Hyperkalemia Renal failure - rare |
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Anti -Platelet Agents
Name 'em oral - 4 drugs IV - 3 drugs |
Anti -Platelet Agents
Oral - long term use Aspirin (ASA) Ticlid ( ticlopidine) Plavix (clopidogrel bisulfide) Persantine (dipyridamole) IV - short term use Aggrastat (tirofiban) Integrilin (eptifibatide) ReoPro (abciximab) |
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Anti -Platelet Agents
Action |
Anti -Platelet Agents
Suppress platelet aggregation Prevent clots in ARTERIES (not veins) Oral - lasts 7-10 days after last dose IV- stops within 4 hrs. |
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Anti -Platelet Agents
Aspirin |
Anti -Platelet Agents
Prevention of first MI - prophylaxis Prevents re-infarction after previous MI Prevents stroke - hx of TIA's Give at first symptoms of MI - MONA |
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MONA
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Treatment of MI
Morphine Oxygen Nitroglycerin Aspirin |
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Anti -Platelet Agents
Plavix and Ticlid |
Anti -Platelet Agents
Ticlid - approved for stroke Plavex - Approved for stroke & MI |
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Anti -Platelet Agents
Persantine (dipyridamole) |
Anti -Platelet Agents
Approved for use after heart valve replacement ONLY |
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Anti -Platelet Agents
Aggrastat Integrilin ReoPro |
Anti -Platelet Agents
IV short term use prevents ischemic events ACS Following pertinacious coronary interventions |
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Vytorin (Ezetimibelsimvastain) is a combination of what 2 drugs?
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Zocor (Simvastain)
Zetia (Exetimibe) |
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Pt. needs a drug that will block cholesterol. What is the best drug?
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Vytorin (Ezetimibelsimvastian)
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Pt. has increase triglycerides, which lipid lowering agent is the best choice?
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Niacin (Nicotinic acid)
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When pt is on "statins" what should you monitor?
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Liver function test. (b/c these drugs can cause hepatotoxicity)
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GI disturbances, gallstones, myopathy and liver injury are adverse effects of what lipid lowering agents? HINT: There are 2
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Lopid (Genfibrozil)
Tricor (Fenofibrate) |
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Anti -Platelet Agents
Adverse effects - ASA |
Anti -Platelet Agents
GI Bleeding Hemorrhagic stroke |
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Anti -Platelet Agents
Adverse effects - Ticlid |
Anti -Platelet Agents
Potential life threatening hematologic reactions |
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Anti -Platelet Agents
Adverse effects - Plavix |
Anti -Platelet Agents
Same as ASA GI Bleeding Hemorrhagic stroke |
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Anti -Platelet Agents
Adverse effects Aggrastat Integrilin Reopro |
Anti -Platelet Agents
Risk for hemmorrhage |
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Opioid Analgesic
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Opioid Analgesic
Morphine Sulfate |
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Not very many people can handle taking Niacin. What is making them feel uncomfortable?
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Intense flushing (they feel BURNING all over their body)
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What is the most common symptom of Dig Toxicity?
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Bradycardia
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2 HUGE/MAIN symptoms of Dig toxicity.
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Anorexia N/V
Change in mental status |
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Opioid Analgesic
Action |
Opioid Analgesic
Pain relief Arterial some dialation - reduce afterload Relaxes pt Reduces anxiety |
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Opioid Analgesic
Adverse effects |
Opioid Analgesic
Hypotension Sedation Nausea & vomiting Urinary retention |
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"ASE"
Clot Busters |
Thrombolytic (fibrinolytic) Therapy
|
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Thrombolytic (fibrinolytic) Therapy
Name 'Em |
Thrombolytic (fibrinolytic) Therapy
Streptase (streptokinase) Activase (altepase tPA) Retavase (retaplase) Eminase (antistreplase) Abbokinase (Urokinase) TTNKase (tenecteplase) |
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Thrombolytic (fibrinolytic) Therapy
Action |
Thrombolytic (fibrinolytic) Therapy
Lyse existing clots Digest fibrin in clots - degrades fibrinogen & other clotting agents |
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Thrombolytic (fibrinolytic) Therapy
Use |
Thrombolytic (fibrinolytic) Therapy
Early MI - Time is muscle Pulmonary embolism Ischemic stroke Clearance of catheters - central or PICC lines |
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"Statin"
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Lipid lowering agents
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Lipid lowering agents
Name the "statins" (6 of 'em) |
Lipid lowering agents - "statins"
Zocor (simvastatin) Lipitor (atovastatin) Lescol (fluvastatin) Mevacor (lovastatin) Pravachol (pravastatin) Vytorin (ezetimbelsimvastatin) |
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Lipid lowering agents
Name the Non "statins" 6of 'em |
Lipid lowering agents
Questran (cholestyramine) Colestid (colestipol) Lipid (gemfibrozil) Tricor (fenofibrate) Zetia (ezetimibe Niacin (nicotinic acid) |
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Lipid lowering agents
Good for pts with very high cholesterol ( Zocor + Zetia) |
Lipid lowering agents
Vytorin (ezetimbelsimvastatin) |
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Lipid lowering agents
Overall action |
Lipid lowering agents
Lower lipid levels Prevent atherosclerosis |
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Lipid lowering agents
Bile acid sequestrates (fat sticks to it) |
Lipid lowering agents
Questran (cholestyramine) Colestid (colestipol) |
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Lipid lowering agents
Fibrates |
Lipid lowering agents
Lopid (gemfibrozil) Tricor ( fenofibrate) |
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Lipid lowering agents
Fibrates - Action |
Lipid lowering agents
Decreases triglycerides Increases HDL |
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Lipid lowering agents
Action of Zetia and Niacin |
Lipid lowering agents
Zetia - Block cholesterol absorption in GI track Niacin - Drug of choice for high Triglycerides |
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Lipid lowering agents
Adverse effect of Statins |
Lipid lowering agents
Hepatotoxicity Myopathy - rare enlargement of heart muscle |
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Lipid lowering agents
Adverse effect of Bile acid sequestrants |
Lipid lowering agents
Constipation Bloating |
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Lipid lowering agents
Adverse effect of Fibrates |
Lipid lowering agents
GI disturbances Gallstones Myopathy Liver damage |
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Lipid lowering agents
Adverse effect of Niacin |
Lipid lowering agents
Intense flushing Hepatotoxicity elevate homecysteine (giving false reading for inflammation) |