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108 Cards in this Set

  • Front
  • Back
Plavix is approved for?
Prevention of stroke and MI
Most common and predictable angina is?
Stable Angina
Pt. is most at risk for ____ when they have unstable angina
Heart Attack
Atypical, and caused by coronary artery spasm with or without atheroscleroric lesion is _____angina
Prinzmetals Angina
Which is more severe? ACS or Angina?
ACS (acute coronary syndrome)
This inversion can occur as a result of decreased oxygen
T-wave inversion
What EKG abnormality is specific to MI
ST segment elevation
What occurs with Pathologic Q-wave? Indicates?
Q wave is longer than R wave. Indicates past MI
Which enzymes are SPECIFIC TO CARDIAC MUSCLES?
CK-MB and Troponin
Marker that measures for presence of inflammation=
C-reactive protien
You're 3x more likely to develop CAD if your total cholesterol is
>260
Desirable LDL is
<130
Optimal LDL is
<100
MD needs to check motion of pt's heart, valve function and EF. What test will he preform?
Echocardiogram
Nitrates act on what? to produce what?
Vascular smooth muscle to produce dilation.
Explain reflex tachycardia
As BP drops, our bodies will become
tachy to try and compensate for the low BP
How do Beta Blockers help with MI?
Reduces pain, infarct size, mortality and risk for re-infarction.
How fast would you expect sub-lingual nitrates to work?
1-3 minutes
How do Beta blockers relieve angina?
Bring O2 demand back in balance with O2 supply
3 main uses of ACE inhibitors
Hypertension, heart failure, MI
Pt. comes in with headache, orthostatic hypotension and reflex tachycardia. You take a look at this meds and realize he is having adverse affects of what medication?
Nitrates
Nitrates primarily act on?
veins
When is Nitroglycerin used in IV drip?
Acute MI and perioperative hypertension
Immediate actions in the ER when a pt comes in with chest pain is?
M-Morphine Sulfate
O- Oxygen
N- Nitroglycerin
A- Asa
What types of people have the greatest risk of restenosis?
Diabetics
Which heart procedure is also called myocardial revascularization?
CABG (coronary artery bypass graft)
Name all heart procedures where the heart is beating "off pump"
MIDCAB (minimally invasive direct cornary bypass graft)

OPCAB (off pump coronary artery bypass)
Pt. has too much plaque, it too many arteries, the doctors can do nothing else. The try one last effort to restore O2 to the heart. What will they perform?
Transmyocardial laser revascularization (TMLR)
Phase 3 of Cardiac rehab would be?
At home
What is considered the "silent disease"
Hypertension
What makes hypertension so dangerous?
Target organ damage
Which diuretic is the first choice to treat hypertension?
HCTZ Hydrochlorothiazide
"Bs" Are Funny...LOL
Beta Blockers
Nitrates - Action
Nitroglycerinst pain
Dilation of arteries and primarily VEINS
Acts on vascular smooth muscle
= vasodialation
decreases cardiac O2 demand
slows down venous return to heart
Nitrates
Nitroglycerin - 4 types of ingestion
sublingual: Nitrostat, Nitroquick
transdermal: Nitro-dur, Transderm-Nitro
topical ointment: Nitrobid
IV: Nitro-bid IIV
Isosorbide mononitrate
Nitroglycerin
Oral tablet IR: ISMO, Monoket
Oral Tablet ER: Imdur
Isosorbide dinatrate
Nitroglycerin
Sublingual: Isordil, Sorbitrate
Chewable tablets: Sorbitrate
Oral tablet IR: Isordil titradose, Sorbitrate
Oral Tablet SR:I Isoril Tembids
Nitrates
Adverse Effects
Headache
Orthostatic hypotension
Reflex tachycardia
Nitrates
Uses
Angina Pain
Angina Prophylaxis
Acute MI and perioperative hypertension (IV)
Nitrates
When to go to hospital
3 doses 5 minutes apart.... if not working...no pain relief...call 911!
"B's" are Funny...LOL
Beta Blockers

Anti Hypertensive
Beta Blockers... name them
Inderal (propranolol)
Lopressor (metoprolol)
Tenormin (Atenolol)
Troprol/Lopressor (metoprolol)
Timoptic (timolol)
Coreg (carvedilol)
Normodyne/Trandate (labetalol)
Beta Blockers
Action
block beta receptors=reduces heart rate, reducing the workload
Reduces force of contraction
Reduces speed of conduction thru AV Node
Beta Blockers
Used for...?
Angina
MI
CHF (Coreg - carvedilol)
Hypertension
Beta Blockers
Actions on Angina
Decrease workload on heart

Evens out supply/demand for O2 - prevents angina pain
Beta Blockers
Actions on MI
Reduces pain, infarct size, mortality

Prevents re-infarction in ER

Protects heart from stress hormones & adrenaline
Beta Blockers
Actions on CHF
COREG - (carvedilol)

deb's point!
Intermost layer of the heart, thin membrane composed of 3 layers=
Endocardium
What is catecholamine?
Stress hormone stimulated by nicotine
"Gold standard of heart surgeries"
CABG
Stents that are coated with a medication, emits microscopic particles into the artery and helps with plaque. What is this called?
Drug-eluting stents
2 reasons pt would need CABG
Client failed medical management
Advanced disease
What nursing consideration should you think about when taking a radial artery and using it for harvesting?
Test ULNAR artery first! Make sure it works properly, (risky harvest)
Why is the pt's blooded cooled?
Cooled blood requires less O2
Beta Blockers
Caution - Contraindications
Diabetics - masks symptoms of hypoglycemia

Asthma - can cause bronchospasms or bronchodilation
CCB = CCP
Calcium Channel Blockers
Calcium Channel Blockers
Name 'em
Calcium Channel Blockers
Calan ( verapamil)
Cardizen (diltiazem)
Procardia (nifedipine)
Calcium Channel Blockers
Action
Calcium Channel Blockers
Antihypertensive
Block Ca channels in heart
Arteriolar dilation = reduced afterload
Works on arteries only
increase coronary perfusion
Reduces HR
Decreases Myocardial force of contraction=reduced workload
Calcium Channel Blockers
Used for....?
Stable angina - reduces O2 demand

Prinzmetal angina - reduces arterial spasms

Hypertension

Cardiac arrhythmia - Cardizem (diltiazem)
Calcium Channel Blockers

Which one is used mainly for cardiac arrhythmia?
Cardizem (diltiazem)
If you got CHF and Hypertension.... chances are, you're gonna get...
Beta blockers
Ace-Pril
Ace Inhibitors
Ace Inhibitors
Name 'em
Ace Inhibitors
Capoten (captopril)
Vasotec (enalapril)
Zestril or Prinivil (lisnopril)
Altace (ramipril)
Mavik (trandoalpril)
Ace Inhibitors
Action
Ace Inhibitors
Reduces preload and afterload
Promotes H2O lose through kidneys- decreases blood volume ((preload)
Prevents or reduce pathologic changes in heart and vessels
Dilates vessels - mostly arterial (afterload)
Systolic BP > ____ and diastolic > _____ can diagnose hypertension
>140 and >90
Pt's BP is 122/84 what BP category are they in?
Prehypertension
Ace Inhibitors

Used for?
Ace Inhibitors

Hypertension - lisinopril

CHF - reduces workload on heart

MI - reduces mortality, decreases chance of heart failure

Neuropathy - diabetic and non-diabetic - slows renal disease

Can prevents MI, Stroke, death (Altace - ramipril)
Ace Inhibitors

What's up with Altace (ramipril)
Ace Inhibitors

Reduces mortality in pt with hx of stroke, MI,diabetes and PVD
Ace Inhibitors

Adverse Affects
Ace Inhibitors

First dose hypertension

Cough - annoying

Hyperkalemia

Renal failure - rare
Anti -Platelet Agents

Name 'em

oral - 4 drugs
IV - 3 drugs
Anti -Platelet Agents

Oral - long term use
Aspirin (ASA)
Ticlid ( ticlopidine)
Plavix (clopidogrel bisulfide)
Persantine (dipyridamole)

IV - short term use
Aggrastat (tirofiban)
Integrilin (eptifibatide)
ReoPro (abciximab)
Anti -Platelet Agents

Action
Anti -Platelet Agents

Suppress platelet aggregation

Prevent clots in ARTERIES (not veins)

Oral - lasts 7-10 days after last dose

IV- stops within 4 hrs.
Anti -Platelet Agents

Aspirin
Anti -Platelet Agents

Prevention of first MI - prophylaxis

Prevents re-infarction after previous MI

Prevents stroke - hx of TIA's

Give at first symptoms of MI - MONA
MONA
Treatment of MI

Morphine
Oxygen
Nitroglycerin
Aspirin
Anti -Platelet Agents

Plavix and Ticlid
Anti -Platelet Agents

Ticlid - approved for stroke

Plavex - Approved for stroke & MI
Anti -Platelet Agents

Persantine (dipyridamole)
Anti -Platelet Agents

Approved for use after heart valve replacement
ONLY
Anti -Platelet Agents

Aggrastat
Integrilin
ReoPro
Anti -Platelet Agents

IV short term use

prevents ischemic events ACS

Following pertinacious coronary interventions
Vytorin (Ezetimibelsimvastain) is a combination of what 2 drugs?
Zocor (Simvastain)
Zetia (Exetimibe)
Pt. needs a drug that will block cholesterol. What is the best drug?
Vytorin (Ezetimibelsimvastian)
Pt. has increase triglycerides, which lipid lowering agent is the best choice?
Niacin (Nicotinic acid)
When pt is on "statins" what should you monitor?
Liver function test. (b/c these drugs can cause hepatotoxicity)
GI disturbances, gallstones, myopathy and liver injury are adverse effects of what lipid lowering agents? HINT: There are 2
Lopid (Genfibrozil)
Tricor (Fenofibrate)
Anti -Platelet Agents

Adverse effects - ASA
Anti -Platelet Agents

GI Bleeding

Hemorrhagic stroke
Anti -Platelet Agents

Adverse effects - Ticlid
Anti -Platelet Agents

Potential life threatening hematologic reactions
Anti -Platelet Agents

Adverse effects - Plavix
Anti -Platelet Agents

Same as ASA

GI Bleeding

Hemorrhagic stroke
Anti -Platelet Agents

Adverse effects

Aggrastat
Integrilin
Reopro
Anti -Platelet Agents

Risk for hemmorrhage
Opioid Analgesic
Opioid Analgesic

Morphine Sulfate
Not very many people can handle taking Niacin. What is making them feel uncomfortable?
Intense flushing (they feel BURNING all over their body)
What is the most common symptom of Dig Toxicity?
Bradycardia
2 HUGE/MAIN symptoms of Dig toxicity.
Anorexia N/V
Change in mental status
Opioid Analgesic

Action
Opioid Analgesic

Pain relief


Arterial some dialation - reduce afterload

Relaxes pt

Reduces anxiety
Opioid Analgesic

Adverse effects
Opioid Analgesic

Hypotension

Sedation

Nausea & vomiting

Urinary retention
"ASE"

Clot Busters
Thrombolytic (fibrinolytic) Therapy
Thrombolytic (fibrinolytic) Therapy

Name 'Em
Thrombolytic (fibrinolytic) Therapy

Streptase (streptokinase)
Activase (altepase tPA)
Retavase (retaplase)
Eminase (antistreplase)
Abbokinase (Urokinase)
TTNKase (tenecteplase)
Thrombolytic (fibrinolytic) Therapy

Action
Thrombolytic (fibrinolytic) Therapy

Lyse existing clots

Digest fibrin in clots - degrades fibrinogen & other clotting agents
Thrombolytic (fibrinolytic) Therapy

Use
Thrombolytic (fibrinolytic) Therapy

Early MI - Time is muscle

Pulmonary embolism

Ischemic stroke

Clearance of catheters - central or PICC lines
"Statin"
Lipid lowering agents
Lipid lowering agents

Name the "statins"
(6 of 'em)
Lipid lowering agents - "statins"
Zocor (simvastatin)
Lipitor (atovastatin)
Lescol (fluvastatin)
Mevacor (lovastatin)
Pravachol (pravastatin)
Vytorin (ezetimbelsimvastatin)
Lipid lowering agents

Name the Non "statins"
6of 'em
Lipid lowering agents

Questran (cholestyramine)
Colestid (colestipol)
Lipid (gemfibrozil)
Tricor (fenofibrate)
Zetia (ezetimibe
Niacin (nicotinic acid)
Lipid lowering agents

Good for pts with very high cholesterol

( Zocor + Zetia)
Lipid lowering agents

Vytorin (ezetimbelsimvastatin)
Lipid lowering agents

Overall action
Lipid lowering agents

Lower lipid levels

Prevent atherosclerosis
Lipid lowering agents

Bile acid sequestrates
(fat sticks to it)
Lipid lowering agents

Questran (cholestyramine)
Colestid (colestipol)
Lipid lowering agents

Fibrates
Lipid lowering agents

Lopid (gemfibrozil)
Tricor ( fenofibrate)
Lipid lowering agents

Fibrates - Action
Lipid lowering agents

Decreases triglycerides

Increases HDL
Lipid lowering agents

Action of Zetia and Niacin
Lipid lowering agents

Zetia - Block cholesterol absorption in GI track

Niacin - Drug of choice for high Triglycerides
Lipid lowering agents

Adverse effect of Statins
Lipid lowering agents

Hepatotoxicity

Myopathy - rare enlargement of heart muscle
Lipid lowering agents

Adverse effect of Bile acid sequestrants
Lipid lowering agents

Constipation

Bloating
Lipid lowering agents

Adverse effect of Fibrates
Lipid lowering agents

GI disturbances
Gallstones
Myopathy
Liver damage
Lipid lowering agents

Adverse effect of Niacin
Lipid lowering agents

Intense flushing
Hepatotoxicity
elevate homecysteine (giving false reading for inflammation)