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43 Cards in this Set

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  • Back

What components does a nucleotide consist of?

A pentose sugar


A nitrogenous base


A phosphate group

What elements do all nucleotides contain?

C


H


O


N


P

What do nucleotides make up?

Nucliec acids such as DNA and RNA

What is DNA used for?

To store genetic information and instructions and that cells need to grow and develop

What does RNA do?

Produces proteins from specific instructions provided by DNA.

Types of nucleotides and their function

ATP


ADP


Their function is to store and transport energy in cells

What is the pentose sugar in DNA?

Deoxyribose

What is the only thing that changes on each DNA nucleotide?

The bases

What are the four possible bases?

Adenine


Thymine


Cytosine


Guanine

Which are purines?

Adenine


Guanine

Which are pyramidines

Thymine


Cytosine

Difference between purines and pyramidines

Purines have 2 carbon Nitrogen rings joined together whereas pyramidines have a single carbon Nitrogen ring

Is purine or pyramidine smaller?

Pyramidine

The sugar in RNA

Ribose

What are the possible bases in RNA?

Adenine


Uracil


Guanine


Cytosine

How many polynucleotides is RNA made you of?

One

What is the term called wn you add one or more phosphate groups to a nucleotide?

Phosphorylation

What does ADP stand for?

Adenosine


Di


Phosphate

What does ATP stand for?


What separate parts is it made up of?

Adenosine


Tri


Phosphate



Has a ribose sugar


The base adenine


3 phosphate groups

What provides energy for chemical reactions in the cell?

ATP

How is ATP produced? Where does the energy required for this come from?

ADP is phosphorylated using the energy released from the breakdown of glucose during respiration. A phosphate bond is formed.

What does ATP do? Where does it store it?

Stores energy within its phosphate bond. When energy is required this bond is broken down into ADP and a inorganic phosphate again. This energy is used by the cell.

Nucleotides join together to create what?

Polynucleotides

Between what do the nucleotides join up to form a polynucleotide?

The phosphate group of one nucleotide and the sugar of another

What is the bond called in a polynucleotide?

Phosphodiester bond



Consists of two ester bonds and one phosphate group.

What is the single bond in the polynucleotide called?

Ester bonds

What are chains of sugar and phosphates known as?

Sugar- phosphate backbone

How can polynucleotides be broken down into nucleotides again?

By breaking the phosphodiester bonds

How many polynucleotide strands are there in DNA?

2

What is the bonding between the bases?

Hydrogen bonding

Name the complementary Base pairings

Adenine and Thymine


Cytosine and Guanine

How many hydrogen bonds form between each?

A and T = 2 form


C and G = 3 form

What cause the DNA to coil?

The hydrogen bonds

Two joined polynucleotides travel in what direction to each other?

Anti- parallel

What does detergent do in a purification reaction?

Breaks down cell membrane

Process of DNA replication



Step 1:

DNA untwists



DNA helicase breaks down hydrogen bonds Between the two polynucleotides.



This causes the helix to unzip to form two single strands

Process of DNA replication



Step 2:

Each original strand acts as a template for new nucleotides.



These new free floating nucleotides bind to their complementary exposed bases on original strand.

Process of DNA replication:



Step 3:

DNA polymerase then joins the new strands together.



Sugar phosphate backbone forms



Hydrogen bonds form between the bases of the original and new strand



The strands twist into a double helix



What is semi-conservative replication ?

Half of the strands of DNA are new and half are original.

What can computer modelling be used to investigate?

Nucliec acids structure

Describe the structure of DNA

Hydrogen bonding between complementary bases (A and T, G and C) on two antiparallel DNA polynucleotides leads to the formation of a DNA molecule and how the twisting of DNA produces it's double helix shape.

What can a mutation in protein be a result of?

A sigle DNA base could be different. This can alter the sequence of amino acids in proteins. An abnornal protein many be produced as a result.

How is the DNA molecule the same width all the way through

Purines to pyramidines