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16 Cards in this Set

  • Front
  • Back

Complete Blood Count (CBC)

Panel of tests that evaluates 3 types of cells that circulate blood:



1) Eval of WBC:


WBC count


WBC differential



2) Eval of RBC:


RBC count


Hgb


Hematocrit


RBC indices


Reticulocyte count



3) Eval of platelets


Platelet count


Mean platelet volume


Platelet distribution width



RBC

Newborn: 4.4-5.8 x 10^6/uL or 4.4-5.8 x 10^12/L (SI)



Adult male: 4.7-6.1 x 10^6/uL or 4.7-6.1x 10^12/L (SI)



Adult female: 4.2-5.4 x 10^6/uL or 4.2-5.4 x 10^12/L (SI)

# of RBC/mm^3

(# cells x depth factor x diluting factor)/ (length of 2° square x width of 2° square x # of squares) = Rbc/mm^3


WBC

Newborn: 9.0-30.0 x 10^3/uL or 9.0-30.0 x 10^9/L (SI)



Child/adult: 4.8-10.8 x 10^3/uL or 4.8-10.8 x 10^9/L (SI)

# of WBC/mm^3

(# of cells x depth factor x diluting factor)/ (length of 1° sq x width of 1° sq x # of squares) =



(# of WBCs counted on 1 side x 10 x 100)/ (1.0 x 1.0 x 4)

Platelets

130-400 x 10^3/uL or


130-400 x 10^9/L (SI)

# of platelets /mm^3

(# of platelets x depth factor x diluting factor)/ (length of 1° sq x width of 1° x # of squares) =



(# of platelets x 10 x 100)/ (1.0 x 1.0 x 1

Hematocrit (hct)

Measures the percentage of a person's total blood volume that consists of RBCs



Newborn: 53-66%


Adult male: 42-52%


Adult female: 37-47%

Hemoglobin (hgb)

Measures the total amount of the oxygen-carrying protein in the blood



Newborn: 17-23 g/dL


Adult male: 14-18 g/dL


Adult female: 12-16 g/dL

RBC indices

Calculations that provide info on the physical characteristics of the RBCs



Includes


1) MCH


2) MCHC


3) MCV


4) RDW

Mean corpuscular hemoglobin (MCH)

Avg Hgb content of the RBC; Avg mass of Hgb per RBC in a sample of blood



MCH = (Hemoglobin x 10)/ RBC (in millions)



Normal MCH: 27-31 pg

Mean corpuscular hemoglobin concentration (MCHC)

Avg [hgb] per unit volume of RBCs; Concentration of Hgb in a given volume of packed RBCs



MCHC = (hemoglobin x 100)/ hematocrit



Normochromic: 32-36%


Hypochromic: <32%

Mean corpuscular volume (MCV)

Avg volume of RBCs per liter ;Avg volume (size) of single RBC



MCV= (Hematocrit x 10)/ RBC (in millions)



Normocytic: 80-100 fL


Microcytic: <80 fL


Macrocyric: >100 fL

Red blood cell distribution width (RDW)

Coefficient of variation of the red cell volume distribution (variation in size of RBCs)



(Stdev of RBC Volume x 100)/ Mean MCV



Normal value= 11.5%-14.5%


Elevated RDW indicates anisocytosis

Mean platelet volume (MPV)

Avg size of platelets



Normal: 7.4-10.4 fL


Increased in idiopathic thrombocytopenic purpura (ITP)

Erythrocyte Sedimentation Rate (ESR)

Male: 0-15 mm/hr


Female: 0-20mm/hr