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5 Cards in this Set

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  • Back
a drug's distribution depends on what 3 factors?
organ perfusion, protein binding, and lipid solubility
in relation to distribution, name the 4 tissue groups and the % of CO they receive?
Vessel rich- 75%
Muscle-19%
Fat- 6%
Vessel poor- 0%
if a drug is bound to plasma proteins, is it available for uptake?
NO. This is why if the patient has a low albumin level, there will be more free drug available
the redistribuition from the brain to less perfused areas like muscle or fat is responsible for the ________ of effect of some anesthetic drugs
termination
a small Vd means that the drug will stay mostly confined to the intravascular space. This will lead to a high or low plasma concentration?
High. So low VD leads to High plasma concentrations