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48 Cards in this Set

  • Front
  • Back

Thestudy of the brain and the nervous system

Neuroscience

Techniquesthat allow for studying brain activity and structure by obtaining visual imagesin awake humans (CAT scans – computer axial tomography, MRI – Magneticresonance imaging, DTI – Diffusion tensor imaging)

Neuro-imaging

What is a neuron?

The brain’s communicators, a nerve cell - Specialized in communication with each other - 86 billion neurons with 160 billion connections - Unique shape compared to other cells

- Centre of neuron,builds new cell components

Cell Body (SOMA)

- Branchlikeextension that receive information from other neurons

Dendrites

- Tails of theneurons that spread out from cell body and transit information

Axons

- End of axoncontaining synaptic vesicles filled with neurotransmitters

Axon Terminal

- Space betweenneurons where NTs travel

Synapse

- Chemicalmessengers that allow neuron to neuron communication

Neurotransmitters (NTs)

- Cell in thenervous system that plays a role in the formation of myelin and the bloodbarrier


- Responds toinjury, removes debris, and enhances learning and memory (two main types ofglial cells


– Astrocytes and oligodendrocytes) - Controls nutrientsupply to neurons


- Destroys andremoves dead neurons- Provides axonswith myelin sheath

Glial Cells

-Play main role


-Found in bloodbrain barrier


-Increasereliability of neuronal transmission


- Control blood flowin brain

Astrocytes

- Promotes newconnections


- Produce myelinsheath around axons - Myelin Sheath(Glial cells wrapped around axons that act as an insulator of the neuron’ssignal

oligodendrocytes

- Neurons respond toNTs by generating electrical activity


- Resting potential:When the neuron is not being stimulated on inhibited


- Action potential:Electrical impulse that travels down the axon (triggers release ofneurotransmitters)

Electrical Activity in the Brain

Types of Neurotransmitters

• Glutamate


• GABA


• Acetylcholine


• Monoamines


• Neuropeptides


• Anandamides

- Most common neurotransmitters


- Both associated with learning and memory


- Glutamate is excitatory and increases the chance neurons will communicate


- Toxic in high doses, may contribute to schizophreniaand other mental disorders- GABA is inhibitory, dampening neural activity

Glutamate and γ-Aminobutyric Acid(GABA)

- Acetylcholine influences arousal, selective,attention, sleep, and memory(CNS)- Neurons that connect to muscles release acetylcholineto trigger movement (PNS)


- Muscle action, learning and memory

Acetylcholine

- Crucial role inarousal, emotion, and cognition


- Norepinephrine,dopamine, and serotonin

Monoamines

- Brain arousal,mood, hunger, sleep


- Increasescontractions in the heart


- As a stresshormone, affects amygdala to affect attention and responses


- Fight or flightresponse, by triggering the release of glucose from energy stores andincreasing blood flow to skeletal muscle

Norepinephrine

- Plays a major rolein reward-motivated behaviour


- Most types ofreward increase the level of dopamine in the brain


- A variety ofaddictive drugs increase dopamine neuronal activity


- Also plays a rolein decision making and behavioural flexibility

Dopamine

- Regulation ofmood, appetite, and sleep - Has some cognitivefunctions including memory and learning- Modulation ofserotonin at synapses is thought to be a major action of several classes ofantidepressant

Serotonin

- The principlefunction of BLANKis to inhibit the transmission of pain signals orpleasure


- They may alsoproduce a feeling of euphoria(Excitement & happy) very similar to thatproduced by other opioids compound

Endorphins

- Influences eating,motivation, memory, and sleep


- THC compound bindsto same receptors

Anandamides

- target the production or inhabitation of certain NTs


- Opiates mimicendorphins and increase activity (agonists)


- Antagonistsdecrease activity, like dopamine blockers for schizophrenia

Psychoactive drugs

- Ability of thenervous system to change - Neurons change infour ways during development o Growth of dendrites and axons o Synaptogenesis o Pruning (cutting/ reducing something)o Myelination

Neural plasticity

Brain + Spinal cord

CNS

Somatic + Autonomic -> Sympathetic - parasympathetic

PNS

- The forebrain isresponsible for advanced intellectual abilities - Two hemispheres connected by the corpus callosum which allows communication betweenthem - Majority of theforebrain is composed of.... - Can be dividedinto four lobes, each associated with a different function

Cerebral cortex

- Assist in motorfunction, language and memory


- Oversee andorganize most other brain functions (executive functioning)


- The prefrontal cortexis responsible for thinking, planning and language


- Broca’s area –Language area helps control speech production


- Speaking,planning, judging, abstract thinking, personality aspects

Frontal Lobes

- Specialized fortouch and perception - Somatosensorycortex is sensitive to pressure, pain, and temperature - Passes informationto motor cortex every time we reach, grasp or move our eyes - Sense of touch,body position

Parietal lobe

- Lower part of thecerebral cortex, it plays a role in hearing, understanding, language, andstoring autobiographical memories - Contains auditorycortex and Wernicke’s area, responsible for speech comprehension - Sound, speech

Temporal Lobe

Language skills – - Speechcomprehension- Speech production- Phonology - Syntax- Reading- Writing Action skills- Making facialexpressions- Motion detection

Left hemisphere

Coarse language skills- - Simple speech- Simple writing- Tone of voice Visuospatial skills- - Perceptualgrouping - Face perception

Right hemishpere

- The emotional center of the brain that also has a rolein smell, motivation, and memoryLise)

Limbic system

- regulates and controlsinternal bodily states; controls the pituitary gland

hypothalamus

- relays information from the sense organs to primary sensory cortex

Thalamus

plays keyrole in fear, excitement, arousal and motivation

Amygdala

- plays a role inspatial memory; damage causes inability to form new memories

Hippocampus

- Located at very back of the brain- Connects the cerebral cortex and spinal cord- Performs basic bodily functions- Serves as a relay station between the cortex and restof the nervous system- Consists of: reticular activating system and midbrain - Reticular activating system connects the forebrain andcerebral cortex and plays a key role in arousal (damage can result in coma)- Midbrain contributes to movement tracking of visualstimuli, ad reflexes triggered by sound

Brain stem

- Oldest most basic functions, consist of:- Cerebellum, pons, medulla

Hindbrain

- Plays predominant role in our sense of balance andenables us to coordinate movement and learn motor skills Lists

Cerebellum

- Connects cortex to cerebellum and triggers dreams

Pons

- Regulates breathing, heartbeat, and other vitalfunctions

Medulla

- Thick bundle of nerves that conveys signals betweenbrain and body- Sensory nerves carry information from body to brain- Motor nerves carry info from brain to rest of body- Also contains interneurons which allow reflexes tohappen

Spinal Cord

Conveys information from CNS to muscles in body,controlling coordinating voluntary movement

Somatic Nervous System

Controls involuntary actions of our internalorgans and glands; has two divisions

Autonomic nervous system

Division isengaged during a crisis or after actions requiring flight or fight

Sympathetic

Division controls rest and digestion

Parasympathetic

When one is active one is inactive

Somatic vs autonomic