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61 Cards in this Set

  • Front
  • Back
What arteries supply the brain in most species?
Basilar artery and internal carotid artery
What is the Rete Mirabile?
Arteries off the Maxillary artery what supply the brain in pigs, cats and ruminants
* also thought to aid in thermoregulation and intercranial BP
What arteries make up the Circle of Willis?
Rostral Cerebral a
Middle Cerebral a
Cd communicating a
Cd cerebral a
Why is the low pressure system of the CNS clinically relevant?
high risk of infections
Where does the venous blood of the CNS empty?
Dural sinus
transverse sinus
What creates the space of the dural sinuses?
dural reflections of the meninges
What is the arterial blood supply to the arteries?
Ventral spinal artery
Dorsal spinal artery

internal vertebral plexus (venous system in epideral space)
What are clinical causes of occlusion of blood vessels in the spine?
Fibicartilagenous emboli- pieces of intervertebral disc

Ischemic encephalopathy- thrombosis infarction of middle artery
What are meninges and name all 3.
Connective tissues membranes that surround the brain and spinal cord.
Dura mater
Arachnoid mater
Pia mater
What are the functions of the meninges?
1) Protection, circulation and reabsorbtion of CSF
2) conveys arterial vessels into nervous tissue and returns venous blood to dural sinuses
3) divides cranium into smaller compartments
What is Pia mater?
The deepest layer of the meninges, denticulate ligament supports the spinal cord
What is Arachnoid mater?
Middle layer of the meninges
sub arachnoid space is between pia mater and arachnoid mater and contains CSF
What is Dura Mater?
Attaches to the arachnoid later by fibroblast layer and makes subdural space

dura mater is well innervated = pain with meningitis
Epideral space is between dura and periosteum of vertebrae
What can the cerebellomedullary cistern (cisterna magna) be used for?
Collection of CSF

use atlantooccipital joint
What is the clinical relevance to hematomas occupying dural space?
neurological abnormalities
What are dural reflections?
reduce movement of brain with in the brain case during sudden/rapid acceleration or deceleration
*falx cerebri -between 2 cerebral hemispheres
*tentorium cerebelli- transverse dural reflection between cerebrum and cerebellum
What is the ventricular system?
fluid filled cavities within the brain stem and cerebrum that are lined with ependymal cells that produce and circulate CSF
*lateral
*3rd
*4th
*Choroid plexus - connects lateral and 3rd
What is the pathway of CSF?
Lateral ventricle-3rd ventricle-4th ventricle-spinal canal
What is the function of CSF?
Water jacket around nervous tissue
maintain ECF composition
Centers for CO2
leaves subarachnoid space through dural sinus
What is the BBB?
barrier for systemic blood and nervous tissue
only lipophilic and gases pass through
What is decussation?
when nerve fibers cross between centers on opposite sides of the CNS
What is ipsilateral?
dealing with same side
What is contralateral?
dealing with opposite side
What are the 5 lobes of the cortex of the brain?
Frontal
Parietal
Piriform
Occipital
Temporal
What lobe is this, what does it do and what abnormality is seen due to lesions?
Frontal Lobe

somatosensory and motor cortices associated with planning and initiating movement

*delay in initiation of contralateral side
What lobe is this, what does it do and what abnormality is seen with lesions?
Occipital Lobe

Perception and innervation of visual information

*cortical blindness
What lobe is this, what does it do and what abnormality is seen with lesions?
Parietal Lobe

integrates senesory information to produce a 3D map of body's location

*spacial perception problems- hemineglect
What is this Lobe, what does it do and what abnormality is seen with lesions?
Piriform Lobe

perception and interpretation of olfactory (connection to limbic system)

*anosmia
difficult to detect in incomplete deficit
What Lobe is this, what does it to and what abnormality is seen with lesions to this lobe?
Temporal

perception and interpretation of auditory information

*destruction of both sides of cortex results in deafness
What is the Limbic system?
not a discrete anatomical lobe of the cortex that links emotion to cortical structures
What are some components of the limbic system?
Hypothalamus - homeostatsis
Amygdala - emotional memory
Hippocampus - short to long term memory
What are some functions of the Hypothalamus?
regulator of autonomic functions and basic survival

appetite, thirst, temperature control, circadian rhythms, osmoregulation, visceral motor system
What are some functions of the Amygdala?
reactivation of emotional response independent of cortical awareness

behavior modification
What are some functions of the Hippocampus?
converts short term to long term memory and is highly integrated with emotional state
What is consciousness?
an individuals ability to perceive its environment and formulate a voluntary response to stimuli
What is ARAS?
Ascending Reticular Activating System

receives input from all sensory projection pathways and involved in arousal in the cerebral cortex
important in selective attension
What are the 5 mental statuses?
Alert
Dull
Demented -abnormal response
Stupor - no response except for pain
Coma- no response
What is circadian rhythm?
variation in physiological rhythms that occur daily

biological clock
REM sleep
What is Narcolepsy?
cerebral disorder resulting in an episodic and sudden onset REM

cataplexy- sudden marked loss of muscle tone
What is a seizure?
a cortical event characterized by abnormal neuronal discharge which is excessive and hypersynchronized
What is a focus?
abnormal area of the brain where seizures originate

kindling spreading of original
mirror - contralateral
What are the stages of a seizure?
Prodrome
Aura
ictus
Post ictus
Interictal
What are some classifications of seizures?
Partial
Generalized
What is the basal ganglia
group of nuclei in cerebrum for motor control, cognition, emotion, learning
What is a fovea, foveola, macula?
Fovea - area where light rays are optimally focussed asvascular
foveola inner part of fovea
Macula = area centralis
What is the nasal retina?
The contralateral cortex
What is the temporal retinal?
The ipsolateral cortex
Where do ganglion cell axons go after they penetrate the optic disc?
optic nerve is a tract of the brain not a true nerve
axons of ganglion synapse in LGN the thalamic relay nucleus for vision = 4 visual pathways
What are the visual pathways?
Retinogeniculostriate
Retinopretectal
Retinotectal
Retinohypothalmic
What is the vision pathway?
photo receptor-optic nerve-optic chiasm-optic tract-
1 LGN of thalamus
2 tectal region
3 SCN
4 pretectal
What is the vestibular system?
system of special proprioception
deals with maintaining a stable orientation in relation to gravity and motion
What are the rotational axises?
Roll pitch and yaw (x,y,z)
What are the vestibular system receptor organs?
Utricle - sensitive to linear acceleration

saccule- sensitive to linear acceleration

semilunar ducts - sensitive to angular acceleration

involved in motor reflex
What is the vestibular pathway?
CN VIII to vestibular nuclei in the hind brain
information can go
1)up to and out CN III IV and VI
2) cerebellum to med and lat vestibulospinal tract
3) to the thalamus via thalamocortal pathways
What is the organ of corti?
contains receptor cells topped with cilia overlaying the tectorial membrane
How to we ear sound?
pressure captured by pinna, hit tympanic membrane (vibrates) transfers to the perilymph of the inner ear via the vestibular window, which bend cilia causing depolarization and AP in auditory nerve

perceive frequency and amplitude
What is the pathway for sound?
cochlear hair cells of CN VIII - cochlear nuclei- cd colliculus

1) startle response
2) MGN of thalamus - temporal lobe- primary auditory pathway
What are the two types of deafness?
Conduction
Sensorineural
What is Conduction deafness
Deafness because of blockage before vestibular window

infection, mites, occulsion
What is sensorineural deafness?
vestibular window can not transmit sound

congenital, old age, drugs, genetic disposition
What is Tonotopy?
area of the cortex that receive message from different areas of the cochlea and perceive it as pitch