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19 Cards in this Set
- Front
- Back
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Astrocytes
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Physical support and repair
K+ metabolism Removal of excess neurotransmitter Maintains BBB |
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Microglia
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CNS Phagocytes
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Oligodengroglia
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Myelinates multiple axons in CNS
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Schwann cells
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Myelinates 1 PNS axon only
Promotes axonal regeneration |
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C Free Nerve endings
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Unmyelinated and slow
Pain and Temperature |
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A-delta Free nerve endings
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Fast, myelinated fibres
Pain and Temperature |
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Meissner's corpuscles
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Large, myelinated fibres
Position, sense and dynamic ine touch, adapt quickly |
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Pacinian corpuscles
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Large, myelinated fibres
Vibration, pressure |
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Merkel's disks
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Large, myelinated fibres
Position sense, static touch, adapt slowly |
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What are the layers of the peripheral nerves?
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Endoneurium - single nerve fibre
Perineurium Epineurium - dense CT |
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Which regions do you find 5HT?
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Raphe nucleus
(increased in anxiety) |
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Which regions do you find NA?
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Locus ceruleus
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Which regions do you find dopamine?
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Ventral tegmentum and Substantia nigra pars compacta
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Which regions do you find Ach?
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Basal nucleus of Meynert
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Which regions do you find GABA?
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Nucleus accumbens
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What are the three structures that form the BBB?
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1. tight junctions between nonfenestrated capillary endothelial cells
2. Basement membrane 3. astrocyte process |
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Which parts of the brain have no BBB?
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Area postrema - vomiting center
OVLT/Supraoptic crest - osmotic sensing |
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What kind of substances can cross the BBB by diffusion?
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Lipid soluble non polar substances
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Which substances need transport mechanisms to cross the BBB?
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Amino acids and glucose
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