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42 Cards in this Set

  • Front
  • Back
What is a central scotoma?
It is an area of depressed vision that corresponds with the point of fixation and interferes with central vision
It suggests a lesion between the optic nerve head and the chiasm
What are some possible causes of a central scotoma?
unilateral or asymmetrical bilateral scotoma
Methyl alcohol (symmetrical bilateral scotoma)
Vascular lesions - unilateral
gliomas of the optic nerve - unilateral
If you have a bitemporal hemaniopia where is the lesion and what visual loss do you experience?
Lesion is at the optic chiasm and you lose the input from the 2 nasal retinas so you lose peripheral vision on both sides
Where is the lesion in homonoymous hemianopia and what visual loss do you experience?
You will lose vision from one visual field
Lesion is after the optic chiasm
If you have lost vision in the superior visual field what is this called and what has been damaged?
Quadrantanopia
Meyer's loop has been cut (inferior radiation - takes superior visual field)
What causes monoocular visual loss i.e. one eye
a lesion of the retina
What are some common causes of monoocular visual loss?
retinal infarcts
amaurosis fugax
haemorrhage
degeneration or infection
What can cause enlargement of the blind spot? What symptoms might the patient present with?
papilloedema which can produce visual blurring due to enlargement of the blind spot
If the lateral geniculate nucleus is taken out by tumours, infarcts, haemorrhage, infection what finding might you see?
contralateral homonomous hemianopia
Takes out the oppostie visual field
Which artery territory covers optic radiations and what visual finding might you see if they are taken out?
Contralateral quadnatanopias (supioer/inferior)
MCA inferio division - tempral lobe (superior visual loss)
superior division - parietal lobe (inferior visual loss)
If you have a lesion affecting the visual cortex what visual finding might you see?
Macular sparing - vision at the fovea is spared so you see contralateral homonoymous hemianopia with central vision spared
What does amaurosis fugax mean?
transient loss of vision in one or both eyes
What visual finding is highly suggestive of retinal ischaemia?
Transient visual loss descending over the field of vision like a curtain or shade
very uncommonly reported
What are some common causes of transient monovular visual loss?
Ischaemia - most common
- atherothrombosis, embolus, dissection
- carotid artery disease (thromboembolism or hypoperfusion)
Papilloedema
Optic neuropathy (MS)
Ocular disease (glaucoma, hyphema = haemorrhage within anterior chamber)
Giant cell arteritis
What are some causes of transient binocular visual loss?
migraine
seizure
veretbrobasilar ischaemia
What is the aetiology of central retinal artery occlusion?
emboli from carotid arteries or heart
thrombus
temporal arteritis
What features do you present with central retinal artery occlusion?
sudden, painless, severe monoocular loss of vision
relative afferend pupillary defect
What fundoscopy findings suggest central retinal artery occlusion?
cherry red spot at centre of macula
retinal pallor
narrowed arterioles, boxcarring
cotton wool spots
cholesterol emboli (Hollenhorst plaques) usually located at arteriole bifurcation
How do you manage central retinal artery occlusion?
Occular emergency - must attempt to restore blood within 2 hours
massage globe to dislodge embolus
decrease intraocular pressure (topical beta blockers, inhaled O2, CO2, mixture), carbonic anhydrase inhibitor, mannitol
anterior chamber paracentesis
What role does the inferior oblique have?
Extorsion and elevation
What role does the superior oblique have?
Down/intorsion/abduction
How does a 4th nerve palsy present?
eye will be extorted and upward deviated
diplopia when they look down and in
What is internuclear ophthalmoplegia
on gaze away from size of lesion 1) adduction of ipsilateral eye is impaired, contralateral eye can abduct but with nystagmus
What is INO due to?
lesion in medial longitudinal fasciculus which disrupts coordination between VI in pons and contralateral CNIII in midbrain - disrupts conjugate horizontal gaze
How does a third nerve palsy present?
ptosis
eye is down and out (i.e. SO functioning)
mydriasis
can get pupil sparing
When do you get pupil sparing third nerve palsy?
Pupillary constrictor fibres are on the peripheral aspect of CNIII so infarction (affecting centre of nerve) will cause pupillary sparing

Anuerysms - painful CNIII palsy + pupil involvement
Diabetic neuropathy - pupils usually spared
How does a CNVI palsy present?
Inability to abduct eye on affected side
horizontal diplipia, worse on ipsilateral gaze
Common cause of VI palsy?
Raised ICP
Infection, head trauma
neoplasm
inflammation
aneurysm
cavernous sinus thrombosis
Common cause of IV palsy?
Congenital
Traumatic
Idiopathic
What is nystagmus?
rapid, involuntary, small amplitude movements of the eyes that are rhythmic in nature
Jerk: slow drift in one direction with a corrective jerk in the opposite direction
Pendular: slow ossilations to and fro
How do you define the direction of nystagmus?
It's defined by the rapid component of the eye movement
i.e. direction of the fast phase
What is the difference between peripheral and central nystagmus?
Peripheral is unidirectional with the fast phase opposite the lesion and tinnitus or deafness often present
Central is unidirectional or bidirectional and tinnitus or deafness is often absent with the fast phase in the direction of the lesion
What is the cause of most jerk nystagmus?
result of an asymmetry in vestibular inputs in either the central or peripheral nervous system
What are the factors that make up Horner's syndrome?
misosis
Anhydrosis
ptosis
hypochromicheterochromia (irides of different colour)
Describe the relative afferent pupillary defect (Marcus Gunn pupil
Caused by an incomplete optic nerve lesion or severe retinal disease
Light stimulus to the disease pupil evokes a weak response in both eyes but stimulus to the normal eye evokes a brisk response
So when you swing to the abnormal eye after the normal eye the pupils dilate after constricting because they are perceiving less light then there actually is
What is an afferent pupillary defect
it is caused by a complete optic nerve lesion
What is the most common cause of RAPD?
optic neuritis - most common
optic nerve compression
large retinal detachment
central retinal artery/vein occlusion
advanced glaucoma
Difference between two types of macular degeneration
both have central scotomas

dry: d for drusen = yellow spots on Bruch's membrane, caused by geographic atrophy

wet: exudative, choroidal neovascularisation. Leakage of serous fluid and blood can subsequently result in a rapid loss of vision. Carries worst prognosis
Risk factors for macular degeneration
Risk factors

* age: most patients are over 60 years of age
* smoking
* family history
* more common in Caucasians
* high cumulative sunlight exposure
* female sex
Rx for dry macular degeneration
nothing
Rx for wet macular degeneration
* photocoagulation
* photodynamic therapy
* anti-vascular endothelial growth factor (anti-VEGF) treatments: intravitreal ranibizumab
Difference between uveitis and acute angle glaucoma
both red...

* glaucoma: severe pain, haloes, 'semi-dilated' pupil

* uveitis: small, fixed oval pupil, ciliary flush