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70 Cards in this Set
- Front
- Back
What are the four subdivisions of the diencephalon?
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dorsal thalamus, subthalamus, epithalamus, hypothalamus
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This subdivision of the deiencephalon is a primary regulator and coordinator of autonomic, behavioral, and endocrine responses?
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Hypothalamus
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The anterior boundary to the hypothalamus is the (3rd ventricle, lamina terminalis, pituitary gland, subthalamus) ?
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lamina terminalis
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The posterior boundary of the hypothalamus is formed by these?
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Mammillary bodies
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The 3rd ventricle is which boundary to the hypothalamus (anterior, lateral, medial, posterior)
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Medial
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The lateral boundary of the hypothalamus is formed by this subdivision of the diencephalon?
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subthalamus
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What demarcates the hypothalamus dorsally?
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hypothalamic sulcus
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What represents the ventral boundary to the hypothalamus?
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pituitary gland
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The lamina terminalis and subfornical organ are what kinds of organs located just rostral to the hypothalamus. They are technically not part of the hypothalamus.
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CVO (circumventricular organs)
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Do the circumventricular organs have a blood-brain barrier?
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No
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What kinds of roles do the circumventricular organs play lying near the hypothalamus?
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state of peripheral blood, fluid balance, drinking behavior, vasopressin release
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This area is located along the most rostral exent of the third ventricle but not part of the hypothalamus, technically?
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Preoptic area (POA)
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The preoptic area( POA) is involved in what kinds of processes?
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Sexual Pleasures (development, reproduction, arousal, gonadotropic release)
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This nucleus is located within the POA and releases hormones differentially between males and females?
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Sexually dimorphic nucleus
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Neurons within these nuclei located within the supraoptic region produce oxytocin and vasopressin?
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Paraventricular and supraoptic nuclei
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Paraventriculae and supraoptic nuclei send their axons where?
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Posterior lobe of the pituitary
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This nucleus is located within the supraoptic region and recieves projections from the retina AND functions in circadian rhythms?
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Suprachiasmatic Nucleus
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This region of the hypothalamus extends from the infundibulum to the mammillary region?
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Tuberal region
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The functions of this nucleus located within the tuberal region is feeding and body weight regulation?
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Dorsomedial Nucleus
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The function of this nucleus in the tuberal region is sexual behavior and feeding?
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Ventromedial nucleus
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The functions of this nucleus located within the tuberal region are neuroendocrine responses related to it's synthesis and secretion of releasing/inhibiting factors?
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Arcuate Nucleus
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What are the three nuclei found within the tuberal region of the hypothalamus?
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Dorsomedial Nucleus, Ventromedial Nucleus, Arcuate Nucleus
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Neurons within this structure, which lies dorsal to the mammillary bodies within the mammillary region, projects to the spinal cord, regulating autonomic responses?
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Posterior Hypothalamus
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These structures located within the mammillary region function in short term memory?
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Mammillary bodies
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This area of the hypothalamus can be found lateral to the fornix and MMT and is related to many autonomic aspects of survival?
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LHA
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This tract innervates the suprachiasmatic nucleus. It also comes from the retina and optic tract?
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Retinohypothalamic tract
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Pre-commissural fibers from the fornix decend (anterior or posterior) to the anterior commissure, and end in the (mammillary or septal region)?
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anterior, septal
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Post-commissural fibers from the fornix decend (anterior or posterior) to the anterior commissure, and end in the (mammillary or septal region)?
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posterior, mammillary
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This pathway originates in the amygala and ends in the hypothalamus?
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stria terminalis
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This pathway originates in the pyriform cortex AND amygdala, and terminates in the hypothalamus?
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Ventral Amygalofugal Pathway
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Where is the pyriform cortex found?
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rostral temporal cortex of the parahippocampal gyrus
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What are the two reciprocal pathways of the hypothalamus?
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Medial forebrain bundle AND Dorsal Longitudinal Fasciculus
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This reciprocal pathway is an "expressway" traveling through the lateral hypothalamic area and connecting the hypothalamus with the septal region, reticular formation and autonomic nervous system centers of brain stem?
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Medial Forebrain Bundle
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The dorsal longitudinal fasiculus course near the midline of the neuraxis and connects the hypothalamus to what?
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autonomic nervous system centers
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This efferent pathway from the hypothalamus arises from the mammillary bodies and projects to the anterior nucleus of the thalamus?
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Mammillothalamic Tract
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This tract originates from neurons in the supraoptic and paraventricular nuclei and ends in the posterior lobe of the pituitary?
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Hypothalamo-Neurohypophysial Tract
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This efferent pathway is formed by neurons within the arcuate nucleus and some medial hypothalamic areas and ends in the hypophysial portal system?
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Tuberohypophysial Tract
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What is the function of the retino-hypothalamic tract?
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Circadian rhythm
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What is the function of the precommissural fornix?
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Learning and Memory
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What is the function of the post-commissural fornix?
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memory
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What role does the stria terminalis play?
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emotion (flight or fight behaviors and autonomic responses)
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What function does the ventral amygdalofugal pathway play?
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Emotion (from both amygdala and pyriform cortex)
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The medial forebrain bundle functions in what way?
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emotion (septal nuclei); Arousal (reticular formaiton); Autonomic NS (spinal cord)
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The Dorsal Longitudinal Fasiculus does what?
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Autonomic NS
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MMT of the hypothalamus functions in ?
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Memory
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Hypothalmo-neurohypophysial tract functions in ?
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Antidiuresis and Partruition
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Tubero-hypophysial Tract functions in ?
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Numerous Endocrine functions
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Fibers of the tuberohypophysial tract terminate where?
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primary capillary plexuses located in th median eminence and infundibular stem
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These are locate din the median eminence and infundibular stem and take up the releaseing and inhibitory factors from the tuberohypophysial tract?
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Primary Capillary Plexuses "sinusoids"
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These are located within the anterio lobe of the pituitary and transport factors from the primary capillary plexus to the anterior lobe of the pituitary?
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Secondary Capillary Plexus
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What is the pathway of the hypophysial portal system starting with the arcuate nucleus and ending with the general circulation in the body?
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Arcuate nucleus > Primary capillary plexus (in median eminence and infundibular stem) > portal veins > secondary plexus (in anterior lobe) > Anterior Lobe > General Circulation
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This autonomic function is located in the anterior and medial regions of the hypothalamus?
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Parasympathetic
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This autonomic function is localized in the lateral and posterior regions of the hypothalamus?
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Sympathetic
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Input for emotional behavior to the hypothalamus comes from what two structures?
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Cerebral cortex and limbic system
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Lesions that disrupt cortical control of emotion, or affect certain nuclei of the hypothalamus can cause what?
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Sham Rage Reactions
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Stress response pathway recieves inputs from what?
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cerebral cortex and limbic (external danger); CVO and Brainstem cell groups (internal danger)
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Hypothalamic output in the stress response pathways originated in these neurons located in the paraventricular nucleus?
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CRF (corticotropin-releasing factor neurons)
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CRF neurons terminate where?
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primary portal capillary plexus
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CRF activate and release what from the pituitary cells?
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ACTH
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What does ACTH cause adrenal cortical cells to produce and release?
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glucocorticoids
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What are some effects of glucocorticoids?
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liver gluconeogenesis; reduction of inflammation and immune responsivity; termination of stress response by feedback inhibition
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These nerons synthesize vasopressin, and damage of these neurons can lead to diabetes insipidus?
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Supraoptic and paraventricular nuclei
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What are some symptoms of diabetes insipidus?
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increase in output of urine, increase need for intake of fluids
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Some head injury patients present with this disease, as a result from damage of neuron firing and release of vasopressin?
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diabetes insipidus
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The release of this hormone during hemorrhagic shock is a bodies defense mechanism and attempt in raising blood pressure?
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Vasopressin (powerful vasoconstrictor)
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These nuclei secrete a hormone responsible for partruition and the milk letdown reflex?
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Supraoptic and paraventricular (oxytocin)
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What roles may oxytocin perform?
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partruition, milk letdown reflex, maternal behaviors, trust and affliative behaviors
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Korsakoff's syndrome is associated with the degeneration of which structures?
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mammillary bodies; dorsal medial thalamic nucleus; and other structures of the limbic system
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What kind of vitamin deficiency is related to Korsakoffs?
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thiamine
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What are some clinical signs of korsakoff's syndrome?
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antergorade amnesia; compensatory confabulation; hallucinations
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